Acceptability at Recruitment
Acceptability at CT / Work-Up
Individual at Risk
Donor / Recipient
Explanation of Condition
Deficiency of vitamin B12, which is vital for DNA synthesis within every cell. Severe deficiency typically results in anaemia with swollen red blood cells, and nervous system problems.
Deficiency may be dietary, or may due to failure of absorption. One such failure of absorption, pernicious anaemia, is an autoimmune disorder usually caused by the body attacking the lining of the stomach.
Other causes of malabsorption include coeliac disease, small bowel bacterial overgrowth and surgical removal of the stomach.
Acceptable if due to stomach operation or dietary deficiency (e.g. vegan), and donor meets haemoglobin requirements (male >13g/dl, female >11g/dl). Recommend supplementation prior to donation.
Pseudonyms or Related Conditions
Version 1, Edition 2
Date of Last Update
1 June 2016