Acceptability at Recruitment
Acceptability at CT / Work-Up
Individual at Risk
Explanation of Condition
We generally recommend that breast-feeding mothers do not donate and, regardless of breast-feeding, donation is not permitted within six months of a term pregnancy.
However, many breast-feeding donors who are more than six months following delivery feel very strongly that they would like to donate, and would be prepared to stop or suspend breast-feeding at the time of donation.
G-CSF is known to be secreted in breast milk (Kaida et al, Act Haematol 2007): it is unknown whether oral G-CSF would have any clinical effect on the infant.
Breast-feeding donors may donate by PBSC if they are prepared to stop breast-feeding on commencing G-CSF injections and to abstain for one week following the last dose of G-CSF. It is safe for the mother to express before this one-week period has expired, but the expressed milk should be discarded.
Bone marrow harvest
Anaesthetic drugs are generally very short-lived in the maternal blood stream. Breast-feeding may continue up until anaesthetic induction prior to the bone marrow harvest, and mothers may recommence feeding 24 hours following recovery from anaesthetic, i.e after 'waking up'. If any other medications are given around the time of the procedure, such as sedating benzodiazepines (e.g. midazolam/diazepam), or opiates (e.g. morphine/codeine) then advice should be sought from the attending anaesthetist.
Pseudonyms or Related Conditions
Version 1, Edition 1
Date of Last Update
24th October 2012