Central Nervous System Disease

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Acceptability at Recruitment


Acceptability at CT / Work-Up


Individual at Risk

Donor / Recipient

Explanation of Condition

Any disorder affecting the brain or spinal cord.


CNS disease of unknown origin, and clinically isolated syndrome, are reasons for obligatory deferral and to permit individual risk assessment where appropriate.

Not acceptable if

Suffering from dementia or Parkinson disease;

History of CNS disease of unknown or suspected infective aetiology such as Creutzfeld Jacob disease (CJD), optic neuritis, clinically isolated syndrome, transverse myelitis or multiple sclerosis.

Neurodegenerative disease of unknown aetiology.

Stroke, TIA (transient ischaemic attack) or cerebral embolus.

Disability physically prohibits either PBSC or bone marrow donation.

Discuss with medical officer if unclear history or aetiology.

Pseudonyms or Related Conditions


Version 1, Edition 1

Date of Last Update

28th June 2018