Cerebrovascular Disease

Condition

Disease of the vasculature of the brain. This includes:

Stroke / cerebrovascular accident (haemorrhagic or embolic)

Transient ischaemic attack

Intracerebral haemorrhage, including subarachnoid, subdural and extradural bleeds

Guidance at RECRUITMENT

UNACCEPTABLE

Guidance at CT/WORK-UP

UNACCEPTABLE, PERMANENT DEFERRAL

Individual at Risk

Donor

Justification for guidance

Both embolic stroke and intracerebral haemorrhage have been reported as adverse events in stem cell donors. In order to reduce this risk, it is prudent to defer any donor with a history of cerebrovascular disease or accident.

References

Halter J, Kodera Y, Ispizua AU, Greinix HT, Schmitz N, Favre G, et al. Severe events in donors after allogeneic hematopoietic stem cell donation. Haematologica 2009;94(1):94-101.

Version

Version 2, Edition 1

Date of Last Update

9 June 2016