From Anthony Nolan Medical Guidelines
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Fibromyalgia is a disorder of unknown etiology characterized by widespread pain, abnormal pain processing, sleep disturbance, fatigue and often psychological distress. People with fibromyalgia may also have other symptoms; such as, morning stiffness, tingling or numbness in hands and feet, headaches, irritable bowel syndrome, sleep disturbance, cognitive problems with thinking and memory, painful menstrual periods and other pain syndromes. Causes and/or risk factors for fibromyalgia are unknown, but some things have been loosely associated with disease onset: stressful or traumatic events, such as car accidents, post traumatic stress disorder, repetitive injuries, illness (e.g. viral infections), certain diseases (i.e., SLE, RA, chronic fatigue syndrome), genetic predisposition, obesity, neurotransmitter disorders and genetic metabolic disorder. People with fibromyalgia react strongly (abnormal pain perception processing) to things that other people would not find painful.

Acceptability at Recruitment

Not Acceptable

Acceptability at CT / Work-Up

Not Acceptable

Individual at Risk


Justification for Guidance

Due to the fact that the disease does not have a well defined etiology donor as well as recipient may be at risk during or after stem cell donation. The tendency of patients to react strongly to things that other people would not find painful is another justification for deferral for donation.


Version 2, Edition 1

Date of Last Update

9 June 2016