G6PD Deficiency

From Anthony Nolan Medical Guidelines
Jump to navigation Jump to search

Acceptability at Recruitment

NOT ACCEPTABLE

Acceptability at CT / Work-Up

QUALIFIED

Individual at Risk

Donor

Explanation of Condition

Deficiency of an enzyme important in providing energy to cells, particularly red blood cells. Sufferers are prone to breakdown of red blood cells (haemolysis) when exposed to certain drugs or other physiological stresses. This is an X linked red cell enzyme deficiency that is variable in its severity. Suitability as a donor should be discussed with the attending Medical Officer. The condition would be transmissible to recipient of stem cells so Transplant Centres need to undertake their own risk assessment.

Guidance

Discuss with Medical Officer.

Unacceptable if severe.

If mild, may donate. In this case, inform transplant centre. If candidate for BM, discuss with anaesthetist.

Pseudonyms or Related Conditions

Glucose-6-Phosphate Deficiency

Version

Version 1, Edition 1

Date of Last Update

1 June 2016