Hormone Replacement Therapy
Acceptability at Recruitment
Acceptability at CT / Work-Up
Individual at Risk
Explanation of Condition
Many conditions require hormone replacement. Today, most hormones are recreated synthetically in laboratories, and thus have negligible risk of carrying infectious organisms. However, some are still derived from human or animal tissue.
Those derived from human pituitary tissue are no longer used, but people who received them before variant CJD was identified are at risk of having contracted the disease, and thus must not donate.
There is considerable debate about the risk of hormones derived from human urine (usually HCG from pregnant women), but this risk is thought to be extremely small.
Unacceptable if derived from human pituitary tissue. Pituitary derived hormones have not been used in the UK since 1985
Acceptable if entirely synthetic or recombinant hormone used.
If derived from human urine, accept at recruitment and inform transplant centre at CT. Urinary hormones used in fertility treatment are Menopur and Merional HP
What condition hormone treatment was used to treat
When and in which country hormone treatment was given
If for IVF name of drug used
Discuss individual cases with MO if required.
Pseudonyms or Related Conditions
Version 1, Edition 2
Date of Last Update
9 August 2016