PrEP
PrEP – Pre-Exposure Prophylaxis
Contents
Acceptability at Recruitment
Acceptable
Acceptability at CT / Work-Up
Acceptable if the donor has not taken PrEP for at least 3 months + there is low sexual risk behaviour. Please discuss with the MO team.
Otherwise postpone.
Individual at Risk
Recipient
Explanation of Condition
Pre-Exposure Prophylaxis (PrEP) is used to prevent HIV infection
Justification for guidance
PrEP may alter HIV testing, resulting in an unclear or negative result in HIV positive donors, with a potential risk of transmission of this virus to patients.
We care a lot about the health of our donors. If you've been using medications like PrEP or PEP to prevent HIV, it could affect the accuracy of HIV tests for up to 3 months after you stop using them (Seed et al, 2020 - [1]). Because of this, health authorities worldwide, including the UK, advise that if you've used PrEP or PEP in the last 3 months, you shouldn't donate.