Back Conditions

From Anthony Nolan Medical Guidelines
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Acceptability at Recruitment

QUALIFIED

Acceptability at CT / Work-Up

QUALIFIED

Individual at Risk

Donor

General Guidance

In general, donors undergoing a bone marrow collection run the risk of exacerbating pre-existing mechanical back conditions due to the shearing forces applied to the lower back and pelvis during the procedure. However, many such donors may donate by PBSC.

Donors with non-mechanical inflammatory back conditions, particularly those associated with autoimmune disease, such as ankylosing spondylitis, should not donate by either route.

Any donor receiving regular steroid injection should be deferred regardless of current severity of condition

Any donor with a back condition which may physically prohibit the donor transferring to an apheresis couch, or lying in an apheresis couch for at least four hours (venous access is not permitted in a wheelchair), or a back condition which might compromise the safety of the donor or staff during collection should be deferred


Individual Guidance

Back complaints should be considered in the subgroups below

Mild, occasional episodes related to exertion (incl sciatica). Minimal impact on activities of daily living and occasional use of medication

Recruitment - Accept VT - Accept for PBSC only. Can consider BMH on case-by-case basis.

Severe chronic back pain. Impacts on activities of daily living

Recruitment - Defer VT - Defer

History of current or past herniated intevertebral disc

Recruitment - Accept for PBSC only VT - Accept for PBSC only

History of back surgery

Defer if less than 6 months from date of surgery Must be fully recovered from surgery

Recruitment - Accept for PBSC only VT - Accept for PBSC Only

Scoliosis

Recruitment - Accept if no surgery and no impact on daily activities VT - Accept if no surgery and no impact on daily activities


History of fracture, dislocation or instability

Recruitment - Accept for PBSC only provided does not meet criteria for severe chronic back pain VT - Accept for PBSC only provided does not meet criteria for severe chronic back pain


Version

Version 2, Edition 1

Date of Last Update

9 June 2016