Difference between revisions of "Epilepsy"

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==Explanation of Condition==
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Seizures caused by abnormal electrical activity in the brain. These can be secondary (e.g. as a result of a brain injury), or primary, where a precipitating cause is not found.
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==Individual at Risk==
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Donor
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==Acceptability at Recruitment==
 
==Acceptability at Recruitment==
  
 
ACCEPT if seizure-free for the previous 12 months WITHOUT medication.  
 
ACCEPT if seizure-free for the previous 12 months WITHOUT medication.  
  
DEFER if currently requiring medication or seizures are related to an underlying organic pathology (eg [[Cerebrovascular Disease]], Traumatic brain injury, Brain Tumour)
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DEFER if currently requiring medication or seizures are related to an underlying organic pathology (eg [[Cerebrovascular Disease]], traumatic brain injury, [[Brain Tumour]])
  
 
==Acceptability at CT / Work-Up==
 
==Acceptability at CT / Work-Up==
  
 
ACCEPT if seizure-free for the past 12 months WITHOUT medication.  
 
ACCEPT if seizure-free for the past 12 months WITHOUT medication.  
 
  
 
DEFER if currently requiring medication.
 
DEFER if currently requiring medication.
  
==Individual at Risk==
 
Donor
 
 
==Explanation of Condition==
 
Seizures caused by abnormal electrical activity in the brain. These can be secondary (e.g. as a result of a brain injury), or primary, where a precipitating cause is not found.
 
  
 
==Guidance==
 
==Guidance==
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==Pseudonyms or Related Conditions==
 
==Pseudonyms or Related Conditions==
 
Seizures
 
Seizures
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==Justification for guidance==
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There is a potential increased risk for perioperative seizures due to the pre-existent condition or the proconvulsant effect of anaesthetic drugs, and also due to electrolyte changes experience during apheresis.
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Anticonvulsant medications may cause abnormalities in blood counts, which may exacerbate those seen after PBSC.
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==Version==
 
==Version==
Version 1, Edition 1
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Version 2, Edition 1
  
 
====Date of Last Update====
 
====Date of Last Update====
15th June 2012
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9 June 2016

Latest revision as of 18:00, 9 June 2016

Explanation of Condition

Seizures caused by abnormal electrical activity in the brain. These can be secondary (e.g. as a result of a brain injury), or primary, where a precipitating cause is not found.

Individual at Risk

Donor

Acceptability at Recruitment

ACCEPT if seizure-free for the previous 12 months WITHOUT medication.

DEFER if currently requiring medication or seizures are related to an underlying organic pathology (eg Cerebrovascular Disease, traumatic brain injury, Brain Tumour)

Acceptability at CT / Work-Up

ACCEPT if seizure-free for the past 12 months WITHOUT medication.

DEFER if currently requiring medication.


Guidance

Unacceptable if has had an epileptic event in the last year or if there is an underlying organic pathology. Otherwise acceptable.

Pseudonyms or Related Conditions

Seizures

Justification for guidance

There is a potential increased risk for perioperative seizures due to the pre-existent condition or the proconvulsant effect of anaesthetic drugs, and also due to electrolyte changes experience during apheresis.

Anticonvulsant medications may cause abnormalities in blood counts, which may exacerbate those seen after PBSC.

Version

Version 2, Edition 1

Date of Last Update

9 June 2016