Difference between revisions of "Hepatitis B"

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===Infected Current Sexual Partner===
 
===Infected Current Sexual Partner===
Unacceptable if current sexual partner of an individual with active hepatitis B (i.e. non-immune).
+
Acceptable if evidence of past resolved infection or immunity from vaccination:
 +
 
 +
Donor is hep B surface antibody positive and hep B surface antigen negative
 +
 
 +
Core Ab antibody may also be positive if resolved infection
 +
 
 +
HepB PCR negative (performed at medical)
  
 
===Past Infection===
 
===Past Infection===
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More than 12 months from recovery of acute infection  
 
More than 12 months from recovery of acute infection  
  
All serological antigen markers (HBSAntigen, HBeAntigen) are negative, HB core antibody is positive and anti-HBs antibody is positive.
+
All serological antigen markers (HBsAntigen, HBeAntigen) are negative and HB core antibody is positive.
  
 
PCR test (performed at medical) should be negative.
 
PCR test (performed at medical) should be negative.
  
Inform TC as soon as past infection identified
+
Inform TC, donor and donor's GP.
  
 
===Former Sexual Partner===
 
===Former Sexual Partner===
A former sexual partner of an infected individual may donate from one year after last sexual contact if either all serological markers are negative, or positive HB core antibody, anti-HBs>100 and all antigen markers negative.
+
A former sexual partner of an infected individual may donate from four months after last sexual contact if either:
 +
 
 +
All serological markers are negative
 +
 
 +
OR
 +
 
 +
positive HB core antibody, positive Hep B surface antibody and all antigen markers negative.
 +
 
  
 +
Inform transplant centre of all potential exposures. 
  
Inform transplant centre of all potential exposures.
+
Four month deferral may be shortened at discretion of transplant centre
  
 
==Pseudonyms or Related Conditions==
 
==Pseudonyms or Related Conditions==
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==Version==
 
==Version==
Version 1, Edition 1
+
Version 1, Edition 2
  
 
====Date of Last Update====
 
====Date of Last Update====
15th June 2012
+
1 June 2016

Latest revision as of 14:21, 12 June 2019

Acceptability at Recruitment

QUALIFIED

Acceptability at CT / Work-Up

QUALIFIED

Individual at Risk

Recipient

Explanation of Condition

Viral liver infection transmitted through contact with blood or other body fluids, most commonly transmitted through sex, from mother to child, or through contaminated blood products or needles.

Guidance

Discuss each case with medical officer.

Current Infection

Unacceptable if current active infection (HbSAg positive or HBV DNA positive).

Infected Current Sexual Partner

Acceptable if evidence of past resolved infection or immunity from vaccination:

Donor is hep B surface antibody positive and hep B surface antigen negative

Core Ab antibody may also be positive if resolved infection

HepB PCR negative (performed at medical)

Past Infection

May donate if:

More than 12 months from recovery of acute infection

All serological antigen markers (HBsAntigen, HBeAntigen) are negative and HB core antibody is positive.

PCR test (performed at medical) should be negative.

Inform TC, donor and donor's GP.

Former Sexual Partner

A former sexual partner of an infected individual may donate from four months after last sexual contact if either:

All serological markers are negative

OR

positive HB core antibody, positive Hep B surface antibody and all antigen markers negative.


Inform transplant centre of all potential exposures.

Four month deferral may be shortened at discretion of transplant centre

Pseudonyms or Related Conditions

Version

Version 1, Edition 2

Date of Last Update

1 June 2016