Inherited Blood Disorder, family history of

From Anthony Nolan Medical Guidelines
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Acceptability at Recruitment

QUALIFIED

Acceptability at CT / Work-Up

QUALIFIED

Individual at Risk

Recipient

Explanation of Condition

Inherited disorders of blood production include such disorders as Haemoglobin Disorders, G6PD Deficiency Diamond-Blackfan syndrome, Blackfan-Schwachmann syndrome and congenital diserythropoietic anaemia, and inherited immune deficiencies such as Wiscott-Aldrich Syndrome.

Potential donors with a family history of an inherited blood disorder may carry the genetic abnormality that causes the syndrome, even though they do not show symptoms of the illness. This abnormality may be passed on to the recipient of transplant where it may cause clinical symptoms.

Guidance

Refer all cases to the medical officer.

Details of the inherited disease should be noted, as well as the underlying mutation, if known. May join the register only if the potential donor has been tested for this mutation and found to not carry it. Alternatively, if alternative tests exist which make carriage of a particular mutation likelyIf necessary discuss the Specific guidance


Pseudonyms or Related Conditions

Version

Version 1, Edition 1

Date of Last Update

15th June 2012