Difference between revisions of "Malaria"

From Anthony Nolan Medical Guidelines
Jump to navigation Jump to search
 
(30 intermediate revisions by 4 users not shown)
Line 6: Line 6:
  
 
==Individual at Risk==
 
==Individual at Risk==
−
Recipient
+
Recipient/ Donor (if not fully treated)
  
 
==Explanation of Condition==
 
==Explanation of Condition==
Line 14: Line 14:
  
 
==Guidance==
 
==Guidance==
−
====If the donor has visited an endemic area within the last three years and has not suffered a febrile illness====
+
'''Resident''' – A donor who has ever been present in a malaria risk area (or areas), for a continuous period of 6 months or more (at any point in their lifetime)
  
−
Acceptable if more than six months have passed since return from an endemic area. A malaria antibody test will be performed at medical.
+
'''Visitor''' – A donor who has visited or travelled through a malaria risk area (or areas) within the past 12 months
  
−
If less than six months has passed, and if the donor has taken a full course of prophylaxis, the donor may proceed at the transplant centre's discretion. A malaria antibody test will be performed at medical. Inform Transplant Centre at VT.
+
'''Unexplained febrile illness (UFI)''' – A donor who had undiagnosed fever (that could have been malaria) while present in, or within four months of leaving, a malaria risk area.
  
−
====If the donor has had malaria diagnosed====
+
'''Previous diagnosis of malaria''' – A donor who previously had a confirmed diagnosis of malaria, at any point in their lifetime.
  
−
Unacceptable if less than 6 months from recovery and cessation of treatment.
+
For a list and maps of malaria risk areas, please refer to JPAC Geographical Disease Risk Index guidelines[https://www.transfusionguidelines.org/dsg/gdri/guidelines]
  
−
Acceptable if more than 3 years from recovery and cessation of treatment. Malaria antibody screen will be performed at Medical Assessment.
+
'''MAT''': Malarial Antibody Test
  
−
Acceptable if more than 6 months but less than 3 years post recovery and cessation of treatment, but a malaria antibody screen should be performed at VT if possible. TC should be informed at VT.
+
'''NAT''': Nucleic Acid Test (for malaria)
 +
{| class="wikitable"
 +
|-
 +
! Status !!  !!  Action
 +
|-
 +
| Visitor || <4 months since return || Request MAT and NAT
 +
|- 
 +
| || 4-12 months since return || Request MAT
 +
|-
 +
|  || > 12 months since return || Accept, no test
 +
|-
 +
||
 +
|-
 +
| Resident || <4 months since last exposure || Request MAT and NAT
 +
|-
 +
|  || > 4 months since last exposure || Request MAT
 +
|-
 +
| |
 +
|-
 +
| UFI || <4 months since last exposure || Request MAT and NAT
 +
|-
 +
|  || > 4 months since last exposure|| Request MAT
 +
|-
 +
||
 +
|-
 +
| History of malaria || <4 months since recovery || Request MAT and NAT
 +
|-
 +
| || > 4 months since recovery|| Request MAT
  
−
====If the donor has had a febrile illness whilst in a malaria endemic area====
 
−
Accept if more than six months have passed since recovery, or return from an endemic area, whichever was the later, and a validated test for malaria antibody is negative.
 
  
−
====If the donor has lived in a endemic area for a continuous period of six months or more at any time in their life====
+
|}
−
Accept if more than six months have passed since their return and a validated test for malaria antibody is negative.
 
  
−
==Pseudonyms or Related Conditions==
+
==Some important questions to ask when collecting travel history==
 +
1) The exact dates and places (countries/ areas/ cities) that they travelled/ lived
  
 +
2) Was the area rural or cities? What did they do: stayed in resort, travelled to rural areas, volunteer work, etc.
 +
 +
3) Any mosquito bites?
 +
 +
4) Did they take malaria prophylaxis? Where they advised to take malaria prophylaxis?
 +
 +
5) Where they well while travelling/ shortly after coming back?
 +
 +
==Some important questions to ask when collecting previous medical history==
 +
1) When were you diagnosed with malaria? Did you have any symptoms? If so, what symptoms did you have?
 +
 +
2) What treatment did you receive? Did you complete the treatment and given all clear from your doctor?
 +
 +
3) Did you have to be admitted to the hospital for treatment?
  
 
==Version==
 
==Version==
−
Version 1, Edition 1
+
Version 3, Edition 1
  
 
====Date of Last Update====
 
====Date of Last Update====
−
15th June 2012
+
07 December 2023

Latest revision as of 12:07, 18 December 2023

Acceptability at Recruitment

QUALIFIED

Acceptability at CT / Work-Up

QUALIFIED

Individual at Risk

Recipient/ Donor (if not fully treated)

Explanation of Condition

Parasitic infection transmitted by the bite of a female mosquito. Untreated, the condition may be rapidly fatal.

See also Malaria

Guidance

Resident – A donor who has ever been present in a malaria risk area (or areas), for a continuous period of 6 months or more (at any point in their lifetime)

Visitor – A donor who has visited or travelled through a malaria risk area (or areas) within the past 12 months

Unexplained febrile illness (UFI) – A donor who had undiagnosed fever (that could have been malaria) while present in, or within four months of leaving, a malaria risk area.

Previous diagnosis of malaria – A donor who previously had a confirmed diagnosis of malaria, at any point in their lifetime.

For a list and maps of malaria risk areas, please refer to JPAC Geographical Disease Risk Index guidelines[1]

MAT: Malarial Antibody Test

NAT: Nucleic Acid Test (for malaria)

Status Action
Visitor <4 months since return Request MAT and NAT
4-12 months since return Request MAT
> 12 months since return Accept, no test
Resident <4 months since last exposure Request MAT and NAT
> 4 months since last exposure Request MAT
UFI <4 months since last exposure Request MAT and NAT
> 4 months since last exposure Request MAT
History of malaria <4 months since recovery Request MAT and NAT
> 4 months since recovery Request MAT


Some important questions to ask when collecting travel history

1) The exact dates and places (countries/ areas/ cities) that they travelled/ lived

2) Was the area rural or cities? What did they do: stayed in resort, travelled to rural areas, volunteer work, etc.

3) Any mosquito bites?

4) Did they take malaria prophylaxis? Where they advised to take malaria prophylaxis?

5) Where they well while travelling/ shortly after coming back?

Some important questions to ask when collecting previous medical history

1) When were you diagnosed with malaria? Did you have any symptoms? If so, what symptoms did you have?

2) What treatment did you receive? Did you complete the treatment and given all clear from your doctor?

3) Did you have to be admitted to the hospital for treatment?

Version

Version 3, Edition 1

Date of Last Update

07 December 2023

Retrieved from "https://www.med-guidelines.org.uk/index.php?title=Malaria&oldid=1891"