Difference between revisions of "PrEP"

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==Acceptability at Recruitment==
 
==Acceptability at Recruitment==
Acceptable BUT inform donors that they should be off PrEP for 3 months to proceed at VT
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Acceptable
  
 
==Acceptability at CT / Work-Up==
 
==Acceptability at CT / Work-Up==
Acceptable if donor has been off PrEP for at least 3 months + there is low sexual risk behaviour.  
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Acceptable if the donor has not taken PrEP for at least 3 months + there is low sexual risk behaviour. Please discuss with the MO team.
  
 
Otherwise postpone.
 
Otherwise postpone.
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==Explanation of Condition==
 
==Explanation of Condition==
Pre-Exposure Prophylaxis (PrEP) is a course of HIV drugs (Truvada= tenofovir + emtricitabine) taken by HIV negative people who are at high risk of infection with HIV. It lowers the risk of becoming HIV positive. It can be taken either regularly or “on-demand” (before and after sexual encounters).
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Pre-Exposure Prophylaxis (PrEP) is used to prevent HIV infection  
  
 
==Justification for guidance==
 
==Justification for guidance==
Similar to High Risk Sexual Behaviour.
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PrEP may alter HIV testing, resulting in an unclear or negative result in HIV positive donors, with a potential risk of transmission of this virus to patients.  
  
PrEP protects from HIV infection but do not protect against other STDs (sexual transmission diseases) such as gonorrhoea or syphilis. If one of these microorganisms is passed on to an immune-compromised patient, it can be life-threatening. Therefore we have a conservative approach.
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We care a lot about the health of our donors. If you've been using medications like PrEP or PEP to prevent HIV, it could affect the accuracy of HIV tests for up to 3 months after you stop using them (Seed et al, 2020 - [https://espace.library.uq.edu.au/data/UQ_25f1211/UQ25f1211_OA.pdf?Expires=1700906000&Key-Pair-Id=APKAJKNBJ4MJBJNC6NLQ&Signature=RUtNkW7DAeNiYuVCx7khuVhmRY91jP7jWN7OuPW-G6zerKmiY24GmaaZjqR9b5E3aNimH~Hbx8rDtzJt43UFOUe7~C468BE13pofA72j8eox0QT1W7ceXk8itpALlSHUv~wYYXVw2YyzQcKX9G-8dbdLEwg41bGpE7YfG-0Sc0XHT38w64uG9mGdK4-JUt3Kby6MeIgykqqxH74n-~yVoIFmoe81pJtUKidEfZZdiXELpXsb80Aymx-HxZc2vPveVBybbpBy40Lxknt0o9w9t9QyjZgv~zLcz2hdmyx4IWAQBS6~UhtzFYZl~CB~c6-CWcYHHxWI8F42~-xRyvuYMg__]). Because of this, health authorities worldwide, including the UK, advise that if you've used PrEP or PEP in the last 3 months, you shouldn't donate.

Latest revision as of 13:05, 30 November 2023

PrEP – Pre-Exposure Prophylaxis


Acceptability at Recruitment

Acceptable

Acceptability at CT / Work-Up

Acceptable if the donor has not taken PrEP for at least 3 months + there is low sexual risk behaviour. Please discuss with the MO team.

Otherwise postpone.

Individual at Risk

Recipient

Explanation of Condition

Pre-Exposure Prophylaxis (PrEP) is used to prevent HIV infection

Justification for guidance

PrEP may alter HIV testing, resulting in an unclear or negative result in HIV positive donors, with a potential risk of transmission of this virus to patients.

We care a lot about the health of our donors. If you've been using medications like PrEP or PEP to prevent HIV, it could affect the accuracy of HIV tests for up to 3 months after you stop using them (Seed et al, 2020 - [1]). Because of this, health authorities worldwide, including the UK, advise that if you've used PrEP or PEP in the last 3 months, you shouldn't donate.