Difference between revisions of "PrEP"

From Anthony Nolan Medical Guidelines
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==Justification for guidance==
 
==Justification for guidance==
Similar to High Risk Sexual Behaviour:
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Similar to High Risk Sexual Behaviour.
With use of modern screening techniques, the risk of unintended transmission of an infectious disease is very small. Stem cell donors undergo in-depth medical and sexual health questionnaires, and will have a face-to-face interview with donor centre staff, allowing ample opportunity to identify those donors at increased risk of contracting a window-period infection.
 
  
In many cases, the benefit to the recipient of receiving a donation will vastly outweigh the risk of transmission of an infectious agent. Therefore, this time period me be reduced at the discretion of the requesting transplant centre.
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PrEP protects from HIV infection but do not protect against other STDs (sexual transmission diseases) such as gonorrhoea or syphilis. If one of these microorganisms is passed on to an immune-compromised patient, it can be life-threatening. Therefore we have a conservative approach.

Revision as of 13:17, 18 April 2019

PrEP – Pre-Exposure Prophylaxis


Acceptability at Recruitment

Acceptable BUT inform donors that they should be off PrEP for 3 months to proceed at VT

Acceptability at CT / Work-Up

Acceptable if donor has been off PrEP for at least 3 months + there is low sexual risk behaviour.

Otherwise postpone.

Individual at Risk

Recipient

Explanation of Condition

Pre-Exposure Prophylaxis (PrEP) is a course of HIV drugs (Truvada= tenofovir + emtricitabine) taken by HIV negative people who are at high risk of infection with HIV. It lowers the risk of becoming HIV positive. It can be taken either regularly or “on-demand” (before and after sexual encounters).

Justification for guidance

Similar to High Risk Sexual Behaviour.

PrEP protects from HIV infection but do not protect against other STDs (sexual transmission diseases) such as gonorrhoea or syphilis. If one of these microorganisms is passed on to an immune-compromised patient, it can be life-threatening. Therefore we have a conservative approach.