PrEP

From Anthony Nolan Medical Guidelines
Jump to navigation Jump to search

PrEP – Pre-Exposure Prophylaxis


Acceptability at Recruitment

Acceptable BUT inform donors that they should be off PrEP for 3 months to proceed at VT

Acceptability at CT / Work-Up

Acceptable if donor has been off PrEP for at least 3 months + there is low sexual risk behaviour.

Otherwise postpone.

Individual at Risk

Recipient

Explanation of Condition

Pre-Exposure Prophylaxis (PrEP) is a course of HIV drugs (Truvada= tenofovir + emtricitabine) taken by HIV negative people who are at high risk of infection with HIV. It lowers the risk of becoming HIV positive. It can be taken either regularly or “on-demand” (before and after sexual encounters).

Justification for guidance

Similar to High Risk Sexual Behaviour.

PrEP protects from HIV infection but do not protect against other STDs (sexual transmission diseases) such as gonorrhoea or syphilis. If one of these microorganisms is passed on to an immune-compromised patient, it can be life-threatening. Therefore we have a conservative approach.