Pre-Malignant Conditions

==Acceptability at Recruitment==

NOT ACCEPTABLE

Acceptability at CT / Work-Up

QUALIFIED, See below

Individual at Risk

Recipient

Explanation of Condition

Inherited conditions predisposing to risk of developing or transforming to malignancy

Guidance

Dependent on diagnosis, see below

BRCA1/BRCA2 Mutation

Not Acceptable at recruitment Acceptable at VT. Inform TC

Familial Adenomatous Polyposis

Not Acceptable at recruitment If undergoing regular screening programme and no features of malignant change discuss with TC at VT

Version

Version 1, Edition 1

Date of Last Update

1 June 2016

Women with known positivity for BRCA1 or 2 but no history of cancer are acceptable as donors. All such women should have a breast examination performed at work-up.