Difference between revisions of "Thrombophilia"

From Anthony Nolan Medical Guidelines
Jump to navigation Jump to search
 
(2 intermediate revisions by the same user not shown)
Line 15: Line 15:
 
==Guidance==
 
==Guidance==
 
====Unacceptable====
 
====Unacceptable====
Diagnosed thrombophilia in association with at least one episode of thrombosis;
+
Diagnosed thrombophilia in association with at least one episode of thrombosis (Blood Clot);
  
High risk thrombophilia (protein C, protein S or antithrombin deficiency)  '''even''' if the donor has not suffered from thrombosis;
+
Diagnosed high risk thrombophilia (protein C, protein S or antithrombin deficiency)  '''even''' if the donor has not suffered from thrombosis (Blood Clot);
  
 
Diagnosed [[Anti-Phospholipid Syndrome]]
 
Diagnosed [[Anti-Phospholipid Syndrome]]
Line 23: Line 23:
 
====Acceptable====
 
====Acceptable====
  
Low risk thrombophilia (Factor V Leiden, Prothrombin 20210 mutation) with no documented history of thrombosis
+
Diagnosed low risk thrombophilia (Factor V Leiden, Prothrombin 20210 mutation) of donor has no history of thrombosis (blood clot)
  
 
Family history of thrombosis with any thrombophilia other than protein C, protein S or antithrombin deficiency.
 
Family history of thrombosis with any thrombophilia other than protein C, protein S or antithrombin deficiency.
Line 47: Line 47:
  
 
==Version==
 
==Version==
Version 1, Edition 1
+
Version 1, Edition 2
  
 
====Date of Last Update====
 
====Date of Last Update====
 
9 June 2016
 
9 June 2016

Latest revision as of 16:28, 9 June 2016

Acceptability at Recruitment

QUALIFIED

Acceptability at CT / Work-Up

QUALIFIED

Individual at Risk

Donor

Explanation of Condition

A variety of conditions predisposing people to blood clots (thrombosis).

See also Thrombophilia

Guidance

Unacceptable

Diagnosed thrombophilia in association with at least one episode of thrombosis (Blood Clot);

Diagnosed high risk thrombophilia (protein C, protein S or antithrombin deficiency) even if the donor has not suffered from thrombosis (Blood Clot);

Diagnosed Anti-Phospholipid Syndrome

Acceptable

Diagnosed low risk thrombophilia (Factor V Leiden, Prothrombin 20210 mutation) of donor has no history of thrombosis (blood clot)

Family history of thrombosis with any thrombophilia other than protein C, protein S or antithrombin deficiency.

Pseudonyms or Related Conditions

Protein C deficiency

Protein S deficiency

Factor V Leiden

Prothrombin mutation

Lupus anticoagulant

Antiphospholipid antibody

High factor VIII level

Antithrombin deficiency

Homocysteinaemia/MTHFR mutation

Version

Version 1, Edition 2

Date of Last Update

9 June 2016