Thrombophilia

From Anthony Nolan Medical Guidelines
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Acceptability at Recruitment

QUALIFIED

Acceptability at CT / Work-Up

QUALIFIED

Individual at Risk

Donor

Explanation of Condition

A variety of conditions predisposing people to blood clots (thrombosis).

See also Thrombophilia

Guidance

Unacceptable

Diagnosed thrombophilia in association with at least one episode of thrombosis (Blood Clot);

Diagnosed high risk thrombophilia (protein C, protein S or antithrombin deficiency) even if the donor has not suffered from thrombosis (Blood Clot);

Diagnosed Anti-Phospholipid Syndrome

Acceptable

Diagnosed low risk thrombophilia (Factor V Leiden, Prothrombin 20210 mutation) of donor has no history of thrombosis (blood clot)

Family history of thrombosis with any thrombophilia other than protein C, protein S or antithrombin deficiency.

Pseudonyms or Related Conditions

Protein C deficiency

Protein S deficiency

Factor V Leiden

Prothrombin mutation

Lupus anticoagulant

Antiphospholipid antibody

High factor VIII level

Antithrombin deficiency

Homocysteinaemia/MTHFR mutation

Version

Version 1, Edition 2

Date of Last Update

9 June 2016