Difference between revisions of "Toxoplasmosis"
m (Protected "Toxoplasmosis" ([edit=sysop] (indefinite) [move=sysop] (indefinite))) |
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==Guidance== | ==Guidance== | ||
− | |||
− | + | Testing outcomes and recommendations | |
+ | |||
+ | 1) Toxoplasmosis IgM = negative AND Toxoplasmosis IgG = positive or negative | ||
+ | Donor can be cleared | ||
+ | |||
+ | 2) Toxoplasmosis IgM = positive AND Toxoplasmosis IgG = positive | ||
+ | Samples should be sent to Toxoplasma Reference Unit (Public Health Wales) | ||
+ | |||
+ | Repeat IgG and IgM | ||
+ | Dye Test | ||
+ | Toxo PCR | ||
+ | |||
+ | |||
+ | 3) Toxoplasmosis IgM = positive AND Toxoplasmosis IgG = negative | ||
+ | |||
+ | Repeat IgG and IgM | ||
+ | Dye Test | ||
+ | Toxo PCR | ||
+ | |||
+ | Results should be discussed with reference laboratory to determine onset of infection. | ||
+ | |||
+ | Donors should be deferred for 6 months from onset of infection. If there is clinical urgency this can be shortened to 3 months in discussion with Toxoplasma reference unit and transplant centre. | ||
+ | |||
+ | Inform TC in all positive cases (IgG and IgM) | ||
==Pseudonyms or Related Conditions== | ==Pseudonyms or Related Conditions== |
Revision as of 12:29, 9 June 2016
Contents
Acceptability at Recruitment
ACCEPTABLE
Acceptability at CT / Work-Up
QUALIFIED
Individual at Risk
Recipient
Explanation of Condition
Infection causing fever, rash and swollen glands. It is rarely severe in normal individuals, but may cause severe disease in those with a compromised immune system, as well as foetal malformations if a pregnant woman is infected. See also Toxoplasmosis
Guidance
Testing outcomes and recommendations
1) Toxoplasmosis IgM = negative AND Toxoplasmosis IgG = positive or negative Donor can be cleared
2) Toxoplasmosis IgM = positive AND Toxoplasmosis IgG = positive Samples should be sent to Toxoplasma Reference Unit (Public Health Wales)
Repeat IgG and IgM Dye Test Toxo PCR
3) Toxoplasmosis IgM = positive AND Toxoplasmosis IgG = negative
Repeat IgG and IgM Dye Test Toxo PCR
Results should be discussed with reference laboratory to determine onset of infection.
Donors should be deferred for 6 months from onset of infection. If there is clinical urgency this can be shortened to 3 months in discussion with Toxoplasma reference unit and transplant centre.
Inform TC in all positive cases (IgG and IgM)
Pseudonyms or Related Conditions
Toxo
Version
Version 1, Edition 1
Date of Last Update
15th June 2012