Difference between revisions of "Toxoplasmosis"

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==Acceptability at CT / Work-Up==
 
==Acceptability at CT / Work-Up==
QUALIFIED
+
ACCEPTABLE
  
 
==Individual at Risk==
 
==Individual at Risk==
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==Explanation of Condition==
 
==Explanation of Condition==
  
Infection causing fever, rash and swollen glands. It is rarely severe in normal individuals, but may cause severe disease in those with a compromised immune system, as well as foetal malformations if a pregnant woman is infected.
+
Common parasitic infection from cat faeces or eating undercooked meat. It can be spread by transfusion.
 +
It causes fever, rash and swollen glands. It is rarely symptomatic in normal individuals, but may cause severe disease in those with a compromised immune system and foetal malformations in pregnant women.
 
See also [http://en.wikipedia.org/wiki/Toxoplasmosis Toxoplasmosis]
 
See also [http://en.wikipedia.org/wiki/Toxoplasmosis Toxoplasmosis]
  
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1) Toxoplasmosis IgM = negative AND Toxoplasmosis IgG = positive or negative
 
1) Toxoplasmosis IgM = negative AND Toxoplasmosis IgG = positive or negative
 +
 
Donor can be cleared
 
Donor can be cleared
  
  
2) Toxoplasmosis IgM = positive AND Toxoplasmosis IgG = positive
+
2) Toxoplasmosis IgM = positive AND Toxoplasmosis IgG = positive or negative
 +
 
 
Samples should be sent to Toxoplasma Reference Unit (Public Health Wales)
 
Samples should be sent to Toxoplasma Reference Unit (Public Health Wales)
  
 
Repeat IgG and IgM
 
Repeat IgG and IgM
 +
 
Dye Test
 
Dye Test
 +
 
Toxo PCR
 
Toxo PCR
  
  
3) Toxoplasmosis IgM = positive AND Toxoplasmosis IgG = negative
+
MUST NOT DONATE if [[confirmed current infection at the time of donation]].
 
 
Repeat IgG and IgM
 
Dye Test
 
Toxo PCR
 
 
 
Results should be discussed with reference laboratory to determine onset of infection.
 
  
Donors should be deferred for 6 months from onset of infection.  If there is clinical urgency this can be shortened to 3 months in discussion with Toxoplasma reference unit and transplant centre.
+
Once the infection is cured, no deferral time is needed although it is recommended to inform the TC.
  
Inform TC in all positive cases (IgG and IgM)
 
  
 
==Pseudonyms or Related Conditions==
 
==Pseudonyms or Related Conditions==

Latest revision as of 09:56, 2 February 2018

Acceptability at Recruitment

ACCEPTABLE

Acceptability at CT / Work-Up

ACCEPTABLE

Individual at Risk

Recipient

Explanation of Condition

Common parasitic infection from cat faeces or eating undercooked meat. It can be spread by transfusion. It causes fever, rash and swollen glands. It is rarely symptomatic in normal individuals, but may cause severe disease in those with a compromised immune system and foetal malformations in pregnant women. See also Toxoplasmosis

Guidance

Testing outcomes and recommendations

1) Toxoplasmosis IgM = negative AND Toxoplasmosis IgG = positive or negative

Donor can be cleared


2) Toxoplasmosis IgM = positive AND Toxoplasmosis IgG = positive or negative

Samples should be sent to Toxoplasma Reference Unit (Public Health Wales)

Repeat IgG and IgM

Dye Test

Toxo PCR


MUST NOT DONATE if confirmed current infection at the time of donation.

Once the infection is cured, no deferral time is needed although it is recommended to inform the TC.


Pseudonyms or Related Conditions

Toxo

Version

Version 1, Edition 2

Date of Last Update

9 June 2016