Transfusion

From Anthony Nolan Medical Guidelines
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Acceptability at Recruitment

QUALIFIED

Acceptability at CT / Work-Up

QUALIFIED

Individual at Risk

Recipient

Explanation of Condition

Includes transfusion with :

red blood cells

platelets

fresh frozen plasma (FFP)

cryoprecipitate

buffy coat/white cell/neutrophils

intravenous or subcutaneous human normal immunoglobulin

Guidance

Establish:-

What blood component the donor received?

In which country the transfusion was given?

Which year the transfusion was given?


RECRUITMENT - Accept if transfused in UK, Europe, Australia, North America. If transfused outside these regions discuss case with MO

VT - Accept if transfused in UK, Europe, Australia, North America AND inform Transplant Centre. If transfused outside these regions discuss case with MO


UNACCEPTABLE:

1. At any time the donor has:

a) Received, or thinks they may have received, a transfusion of blood or blood components in a country endemic for malaria or South American trypanosomiasis. See ‘Discretionary’ section below for exceptions.

b) Has received regular treatment with blood derived coagulation factor concentrates. Treated with blood derived coagulation factor concentrates. This includes prothrombin complex to reverse over-anticoagulation.

2. Since January 1st 1980:

a) Anywhere in the world, the donor has received, or thinks they may have received, a transfusion with red cells, platelets, fresh frozen plasma (FFP), cryoprecipitate, intravenous or subcutaneous human normal immunoglobulin. This includes mothers whose babies have required intrauterine transfusion.

b) Had a plasma exchange performed.

3. Before January 1st 1999:

Treated with prothrombin complex to reverse over-anticoagulation


For the rest of the case, follow current JPAC guidelines in conjunction with transplant centre:

JPAC Transfusion Guidelines


Pseudonyms or Related Conditions

Blood transfusion

Version

Version 1, Edition 2

Date of Last Update

3 November 2016