Transfusion

From Anthony Nolan Medical Guidelines
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Acceptability at Recruitment

QUALIFIED

Acceptability at CT / Work-Up

QUALIFIED

Individual at Risk

Recipient

Explanation of Condition

Includes transfusion with :

red blood cells

platelets

fresh frozen plasma (FFP)

cryoprecipitate

buffy coat/white cell/neutrophils

intravenous or subcutaneous human normal immunoglobulin

Guidance

Establish:-

What blood component the donor received?

In which country the transfusion was given?

Which year the transfusion was given?


RECRUITMENT - Accept if transfused in UK, Europe, Australia, North America. If transfused outside these regions discuss case with MO

VT - Accept if transfused in UK, Europe, Australia, North America AND inform Transplant Centre. If transfused outside these regions discuss case with MO


UNACCEPTABLE:

1. At any time the donor has:

a) Received, or thinks they may have received, a transfusion of blood or blood components in a country endemic for malaria or South American trypanosomiasis. See ‘Discretionary’ section below for exceptions.

b) Has received regular treatment with blood-derived coagulation factor concentrates. This includes prothrombin complex to reverse over-anticoagulation.

2. Since January 1st 1980:

a) Anywhere in the world, the donor has received, or thinks they may have received, a transfusion with red cells, platelets, fresh frozen plasma (FFP), cryoprecipitate, intravenous or subcutaneous human normal immunoglobulin. This includes mothers whose babies have required intrauterine transfusion.

b) Had a plasma exchange performed.

3. Before January 1st 1999:

Treated with prothrombin complex to reverse over-anticoagulation


For the rest of the case, follow current JPAC guidelines in conjunction with transplant centre:

JPAC Transfusion Guidelines


Pseudonyms or Related Conditions

Blood transfusion

Version

Version 1, Edition 2

Date of Last Update

3 November 2016