Main Page

<mediawiki xmlns="http://www.mediawiki.org/xml/export-0.10/" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.mediawiki.org/xml/export-0.10/ http://www.mediawiki.org/xml/export-0.10.xsd" version="0.10" xml:lang="en">
  <siteinfo>
    <sitename>Anthony Nolan Medical Guidelines</sitename>
    <dbname>localdb</dbname>
    <base>https://www.med-guidelines.org.uk/Main_Page</base>
    <generator>MediaWiki 1.34.1</generator>
    <case>first-letter</case>
    <namespaces>
      <namespace key="-2" case="first-letter">Media</namespace>
      <namespace key="-1" case="first-letter">Special</namespace>
      <namespace key="0" case="first-letter" />
      <namespace key="1" case="first-letter">Talk</namespace>
      <namespace key="2" case="first-letter">User</namespace>
      <namespace key="3" case="first-letter">User talk</namespace>
      <namespace key="4" case="first-letter">Wiki</namespace>
      <namespace key="5" case="first-letter">Wiki talk</namespace>
      <namespace key="6" case="first-letter">File</namespace>
      <namespace key="7" case="first-letter">File talk</namespace>
      <namespace key="8" case="first-letter">MediaWiki</namespace>
      <namespace key="9" case="first-letter">MediaWiki talk</namespace>
      <namespace key="10" case="first-letter">Template</namespace>
      <namespace key="11" case="first-letter">Template talk</namespace>
      <namespace key="12" case="first-letter">Help</namespace>
      <namespace key="13" case="first-letter">Help talk</namespace>
      <namespace key="14" case="first-letter">Category</namespace>
      <namespace key="15" case="first-letter">Category talk</namespace>
    </namespaces>
  </siteinfo>
  <page>
    <title>Main Page</title>
    <ns>0</ns>
    <id>1</id>
    <revision>
      <id>2444</id>
      <parentid>2443</parentid>
      <timestamp>2026-04-28T14:31:53Z</timestamp>
      <contributor>
        <username>Ellouise.Bishop@anthonynolan.org</username>
        <id>13192</id>
      </contributor>
      <comment>/* R */</comment>
      <model>wikitext</model>
      <format>text/x-wiki</format>
      <text xml:space="preserve" bytes="31167">=About the Anthony Nolan Medical and Lifestyle Guidelines=

For potential and current donors, please note that these guidelines are primarily intended for use by Anthony Nolan staff.

The Anthony Nolan Medical and Lifestyle Guidelines are put in place to ensure the safety of both our stem cell donors and the recipients of their donations. 

Because of the volunteer nature of stem cell donation, we have a responsibility to ensure that our donors are able to donate safely, with minimal risk to their own health. For this reason, our medical criteria are  strict, and considerably more strict than medical criteria for having a procedure, such as an operation, for the benefit of your own health. 

Some donor medical conditions present a risk to the '''recipient''' of the donation. In these cases, we may allow a donor to donate because the benefit for the patient of receiving the transplant outweighs the risk.

=Definition=

“Qualified” means the donor is acceptable to proceed at this stage. However, you must review the Guidance section for that medical condition, as additional questions or requirements may apply.

=Guidance for Recruiters=

The list is not exhaustive; therefore, particular cases may require further clarification by our Medical Officer.

IN SUCH CASES PLEASE NOTE THE FOLLOWING:
The volunteer should be asked to complete an application form giving full details of their
medical status ensuring that the following information is given:

*Name of medical condition.
*Date of diagnosis.
*Name of medication(s) taken.
*Length of time medication has been taken.
*Is the medication seen as a short course or long-term prescription?
*Does the volunteer have any limitations to life-style?
*Is the volunteer’s condition regularly assessed by GP/Consultant?

Once the application has been reviewed the donor will be contacted and informed
of the decision.

This list is in place to help us recruit medically eligible volunteer blood stem cell donors.
We have a duty to ensure that volunteer donors are put at minimal risk whilst also considering the safety and outcome for transplant recipients.

The criteria, which we use to assess the suitability of a volunteer to donate, are considerably
more stringent than those taken into consideration for volunteers undergoing a procedure for
their own medical health status.

If you have any queries, please contact the Register Support team as follows:

Telephone 0207 424 6567 (9am – 5pm) or E-mail: register.support@anthonynolan.org

=Recently Updated Guidance=


Review of all guidelines June 2016

=Multiple Medical Conditions=

Some donors will have more than one medical problem, and the potential combinations are too numerous to list in this guidance. Some combinations of conditions will increase the risk of donor harm, despite being acceptable in isolation. 

For example, hypertension, smoking, high cholesterol and diet-controlled diabetes may all be acceptable, but this combination in an older donor would considerably increase their risk of a heart attack or stroke. 

If in doubt, please discuss these donors with the medical officer.

=Post donation guidelines=
[[Post-donation guidelines]]

=Index of Conditions=

==A==

Accident, See [[Fracture]] and/or [[Surgery]]

Abnormal LFTs, See [[Liver Function, Abnormal]]

[[Acetylcholinesterase Deficiency]]

[[Achondroplasia]]

Acitretin, See [[Acne]]

[[Acne]]

[[Acoustic Neuroma]]

Acoustic Schwannoma, See [[Acoustic Neuroma]]

[[Acromegaly]]

[[Actinic Prurigo]]

[[Acupuncture]]

ADD, See [[Attention Deficit Hyperactivity Disorder]]

[[Addison Disease]]

Adenocarcinoma, See [[Malignancy]]

[[Adenoma]]

Adenomyosis, see [[Endometriosis]]

ADHD, See [[Attention Deficit Hyperactivity Disorder]]

Adrenal Hyperplasia, See [[Congenital Adrenal Hyperplasia]]

[[African Trypanosomiasis]]

AIDS, See [[HIV]]

[[Albino]]

[[Alcohol Intake]]

[[Allergy]]

[[Alopecia]]

[[Alpha 1 Antitrypsin Deficiency]]

Alpha Mannosidosis, See [[Inherited Disease]]

[[Alports Syndrome]]

Anabolic Steroids, See [[Addiction and Drug Abuse]]

[[Anaemia]] 

[[Anaesthetic Complications]]

Angina, See [[Heart, Coronary Artery Disease]]

[[Animal Bite]]

[[Ankylosing Spondylitis]] 

Anthrax Vaccine, See [[Immunisation]]

Anti-Inflammatory Drug, See [[Non Steroidal Anti-Inflammatory Drug]]

[[Anti-Phospholipid Syndrome]]

[[Antibiotic Treatment]]

[[Antibodies]] 

[[Anticoagulants]] 

Anticonvulsants, See [[Epilepsy]]

Antithrombin Deficiency, See [[Thrombophilia]] 

[[Anxiety Disorder]] 

Aortic Regurgitation, See [[Heart, Valve Disease]]

Aortic Stenosis, See [[Heart, Valve Disease]]

Aortic Valve Disease, See [[Heart, Valve Disease]]

[[Arachnoid Cyst]]

[[Arnold-Chiari Syndrome]] 

Arrhythmia, See [[Heart, Arrhythmia]]

[[Arthrogryposis]] 

Arthroscopy, See [[Surgery]] 

[[Asperger Syndrome]] 

Aspirin, See [[Non Steroidal Anti-Inflammatory Drug]]

[[Asthma]] 

Atherosclerosis, See [[Heart, Coronary Artery Disease]]

Athlete, See [[Anti-doping guidance]]

Atrial Fibrillation, See [[Heart, Arrhythmia]] 

Atrial Myxoma, See [[Myxoma]]

Atrial Septal Defect (ASD), See [[Heart, Congenital Defect]]

[[Attention Deficit Hyperactivity Disorder]] 

[[Avascular Necrosis]] 

Avodart, See [[Dutasteride]]

Avulsion Fracture (Other Than Spinal), See [[Fracture]]

Avulsion Fracture (Spinal), See [[Back Conditions]]

==B==

[[B12 Deficiency]] 

[[Babesiosis]] 

[[Back Conditions]]

[[Balanitis Xerotica Obliterans (BXO)]] 

[[Barrett's oesophagus]]

[[Basal Cell Carcinoma]]

BCG Vaccination, See [[Immunisation]]

Behchet's, See [[Vasculitis]]

[[Bells Palsy]] 

Benign Essential Tremor, See [[Essential Tremor]]

Benign Ethnic Neutropenia, See [[Neutropenia]]

Benign Intracranial Hypertension, See [[Idiopathic Intracranial Hypertension]] 

[[Benign Positional Vertigo]]

[[Benign Prostatic Hyperplasia]] 

Berger Disease, See [[Kidney Disease]] 

Beta Thalassemia, See [[Haemoglobin Disorder]]

Bilateral Scleritis, See [[Eye Disease]]

Bilharzia, See [[Schistosomiasis]]

[[Bipolar Affective Disorder]]

Bisexual, See [[Sexual Orientation]] 

[[Bleeding Disorder]]

Blocked Artery (Heart), See [[Heart, Coronary Artery Disease]]

Blood Clot, See [[Thrombosis]]

Blood Pressure, See [[Hypertension]]

Blood Transfusion, See [[Transfusion]]

[[Body Piercing]] 

Bone Density (Abnormal), See [[Osteoporosis]]

Bone Graft, See [[Surgery]] and/or [[Back Conditions]]

Bowens Disease, See [[Malignancy]] 

BPH, See [[Benign Prostatic Hyperplasia]]

[[Brain bleed]]

[[Brain Injury]]

Brain Surgery, See [[Neurosurgery]]

[[Brain Tumour]]

BRCA Mutation, See [[Pre-Malignant Conditions]] 

[[Breast Augmentation (Implants)]] 

[[Breast Feeding]]

[[Bronchiectasis]] 

Bronchitis, See [[Infection, Acute]]

Brown-Sequard Syndrome, See [[Central Nervous System Disease]]

[[Brucellosis]] 

[[Bursitis]]

==C==

[[C1 Esterase Inhibitor Deficiency]] 

Cancer, See [[Malignancy]]

[[Candida Infection]]

Candidiasis, See [[Candida Infection]]

Carcinoid Syndrome, See [[Malignancy]]

Cardiac Failure, See [[Heart, Muscle Disease]]

Cardiac Syndrome X, See [[Heart, Coronary Artery Disease]]

Cardiomegaly, See [[Heart, Muscle Disease]]

Cardiomyopathy, See [[Heart, Muscle Disease]] 

[[Carpal Tunnel Syndrome]] 

Cat-Scratch Fever, See [[Infection, Acute]]

[[Causalgia]] 

Cellulitis, See [[Infection, Acute]] 

[[Central Nervous System Disease]]

Cerebral Malaria, See [[Malaria]] 

[[Cerebral Palsy]] 

[[Cerebroretinal Angiomatosis]]

[[Cerebrovascular Disease]]

[[Cervical Carcinoma In-Situ]]

Cervical Intraepithelial Neoplasia (CIN), See [[Pre-Malignant Conditions]]

Cervical Spondylosis, See [[Back Conditions]]

Chagas Disease, See [[South American Trypanosomiasis]]

Charcot Marie Tooth Syndrome, See [[Hereditary Motor Sensory Neuropathy]]

Chiari Malformation, See [[Arnold-Chiari Syndrome]]

[[Chicken Pox]] 

Chikungunya, See[[Tropical Viruses]]

Chlamydia, See [[Infection, Acute]]

Cholecystectomy, See [[Surgery]]

Cholecystitis, See [[Gall-Bladder Disease]]

[[Chondromalacia Patellae]] 

Christmas Disease, See [[Bleeding Disorder]]

Chronic Fatigue Syndrome, See [[Myalgic Encephalomyelitis]] 

[[Chronic Obstructive Pulmonary Disease]]

[[Cirrhosis]] 

CJD, See [[Prion-Associated Disease]]

Clap, See [[Gonorrhoea]]

[[Clinical Trial]]

[[Cluster Headache]]

CMV, See [[Cytomegalovirus]]

Coagulation Disorder, See [[Bleeding Disorder]] or [[Thrombophilia]]

Coarctation of the aorta, See [[Heart, Congenital Defect]]

Coccydynia, See [[Back Conditions]] 

[[Coeliac Disease]]

Coldsore, See [[Herpes Simplex Virus]]

[[Colitis]]

Cone Biopsy, See [[Cervical Carcinoma In-Situ]]

[[Congenital Adrenal Hyperplasia]]

Congenital Dwarfism, See [[Achondroplasia]]

[[Congenital Naevus]]

[[Congo Fever]]

Conn Syndrome, See [[Hyperaldosteronism]]

[[ Considerations for transgender and gender non-binary individuals ]]

[[Conversion Disorder]] 

COPD, See [[Chronic Obstructive Pulmonary Disease]]

[[Corneal Transplant]] 

Coronary Artery Disease, See [[Heart, Coronary Artery Disease]]

Coronary Thrombosis, See [[Heart, Coronary Artery Disease]]

[[Coronavirus]]

[[Costochondritis]]

[[Cow Pox]] 

Coxsackie Virus, See [[Infection, Acute]]

Creutzfeld-Jacob Disease, See [[Prion-Associated Disease]]

[[Crigler-Najjar Sydrome]] 

Crimean Fever, See [[Brucellosis]]

Crimean-Congo Haemorrhagic Fever, See [[Congo Fever]]

Crohns Disease, See [[Inflammatory Bowel Disease]]

Crush Fracture (Spinal), See [[Back Conditions]]

[[Cushing Syndrome/Disease]] 

Cutaneous Leishmaniasis, See [[Leishmaniasis]]

[[Cystic Fibrosis]] 

[[Cystinuria]] 

[[Cysts]] 

[[Cytomegalovirus]]

==D==

[[Darier Disease]] 

Deep Vein Thrombosis, See [[Thrombosis]]

Dengue Fever, See [[Tropical Viruses]] 

[[Depression]] 

[[Dermatitis]] 

[[Dermatitis Herpetiformis]] 

[[Dermatomyositis]] 

[[Dextrocardia]]

[[Diabetes Insipidus]] 

[[Diabetes Mellitus]]

Diamond-Blackfan Syndrome, see [[Inherited Disease]]

Diclofenac, See [[Non Steroidal Anti-Inflammatory Drug]]

[[Disabled Volunteer]]

Disc (Removal/Micro Discectomy), See [[Back Conditions]]

Disc Protrusion/Prolapse, See [[Back Conditions]]

Discoid Lupus, See [[Systemic Lupus Erythematosus]]

[[Diverticulitis]]

Double-Jointed, See [[Hypermobility Syndrome]]

[[Down Syndrome]] 

Drug Abuse, See [[Injection of Non-Prescription drugs]]

Drug Treatment, See [[Medications]] 

Drug Trial, See [[Clinical Trial]]

[[Duodenal Ulcer]] 

[[Duplex Kidney]] 

[[Dutasteride]]

Dwarfism, See [[Achondroplasia]]

Dysentery, See [[Infection, Acute]]

Dysfibrinogenaemia, See [[Bleeding Disorder]]

Dyspepsia, See [[Gastro-Oesophageal Reflux]]

[[Diastasis Symphysis Pubis]] 

Dystonia, See [[Central Nervous System Disease]]

==E==

Ebola Fever,See [[Viral Haemorrhagic Fever]]

EBV, See [[Epstein-Barr Virus]]

Eclampsia, See [[Pre-Eclampsia]]

[[Eczema]]

[[Ehlers-Danlos Syndrome]] 

[[Electrolysis]] 

Elephantiasis, See [[Filariasis]]

Emphysema, See [[Chronic Obstructive Pulmonary Disease]]

[[Encephalitis]]

[[Endocarditis]] 

[[Endometriosis]] 

[[Eosinophilic Oesophagitis]]

[[Epidermolysis Bullosa]] 

[[Epilepsy]] 

Episcleritis, See [[Eye Disease]]

[[Epistaxis]]  

[[Epstein-Barr Virus]]

ERPC (Evacuation Of Retained Products Of Conception), See [[Surgery]]

[[Erysipelas]] 

[[Erythema Multiforme]] 

[[Erythema Nodosum]] 

[[Erythromelalgia]] 

Essential Thrombocythemia, See [[Myeloproliferative Neoplasm]]

[[Essential Tremor]]

[[Eye Disease]]

==F==

[[Factor 12 (XII) Deficiency]]

Factor 5 Leiden, See [[Thrombophilia]]

Factor 5 (V), 7 (VII), 8 (VIII), 9 (IX), 11 (XI) Deficiency, See [[Bleeding Disorder]]

Factor V Leiden, See [[Thrombophilia]]

Familial Hypercholesterolaemia, See [[Hyperlipidaemia]]

[[Familial Mediterranean Fever]]

Familial Adenomatous Polyposis, See [[Pre-Malignant Conditions]] 

[[Fat Embolism]] 

Felty Syndrome, See [[Rheumatoid Arthritis]]

Fertility Treatment, See [[Hormone Replacement Therapy]]

[[Fibroids]] 

[[Fibromyalgia]] 

Fibrosarcoma, See [[Malignancy]] 

[[Fibrosing Alveolitis]] 

[[Filariasis]] 

[[Finasteride]]

Flu, See [[Influenza]]

[[Folate Deficiency]] 

[[Fracture]]

[[Fragile X Syndrome]]

[[Functional neurological disorder]]

==G==

[[G6PD Deficiency]]

[[Galactosaemia]] 

[[Gall-Bladder Disease]] 

Gallstones, See [[Gall-Bladder Disease]]

Gammopathy, See [[Malignancy]]

[[Ganglion]] 

[[Gastrectomy]]

[[Gastric Ulcer]]

[[Gastritis]] 

[[Gastro-Oesophageal Reflux]] 

[[Gaucher Disease]] 

Gender Reassignment See [[Considerations for transgender and gender non-binary individuals]]

Genetic Traits, See [[Inherited Disease]]

Genital Herpes, See [[Herpes Simplex Virus]]

[[Genital Warts]]

[[Giant Cell Tumour]] 

[[Giardiasis]] 

[[Gilbert Syndrome]] 

[[Gilles De La Tourette Syndrome]] 

Glandular Fever, See [[Epstein-Barr Virus]] 

Glaucoma, See [[Eye Disease]] 

[[Glomerulonephritis]] 

Gluten Intolerance, See [[Coeliac Disease]]

Goitre (Enlarged Thyroid), See [[Thyroid Disease]]

[[Gonorrhoea]]

[[Gout]]

[[Granuloma Annulare]] 

Graves Disease, See [[Thyroid Disease]]

Growth Hormone Therapy, See [[Hormone Replacement Therapy]]

[[Guillain-Barre Syndrome]] 

Guttate Psoriasis, See [[Psoriasis]]

==H==

H. Pylori, See [[Helicobacter Pylori]]

[[Haemangioma]]

[[Haematemesis]]

[[Haematuria]]

[[Haemochromatosis]] 

Haemoglobin C, See [[Haemoglobin Disorder]]

Haemoglobin Camden, See [[Haemoglobin Disorder]]

Haemoglobin D, See [[Haemoglobin Disorder]]

[[Haemoglobin Disorder]]

Haemoglobin E, See [[Haemoglobin Disorder]]

Haemoglobin Level, See [[Anaemia]]

Haemoglobin S, , See [[Haemoglobin Disorder]]

[[Haemolytic Anaemia]]

[[Haemolytic Uraemic Syndrome]] 

Haemophilia, See [[Bleeding Disorder]]

Haemophilia Carrier, See [[Bleeding Disorder]]

[[Hand Foot And Mouth]]

Hashimotos Thyroiditis, See [[Thyroid Disease]]

Heart Attack, See [[Heart, Coronary Artery Disease]]

Heart Block, See [[Heart, Arrhythmia]]

Heart Murmur, See [[Heart, Valve Disease]]

[[Heart, Arrhythmia]]

[[Heart, Congenital Defect]]

[[Heart, Coronary Artery Disease]]

[[Heart, Muscle Disease]]

[[Heart, Valve Disease]]

Heavy Periods, See [[Menorrhagia]]

[[Helicobacter Pylori]] 

[[HELLP Syndrome]] 

Henoch-Schonlein Purpura, See [[Vasculitis]] 

[[Hepatitis A]]

[[Hepatitis B]]

[[Hepatitis C]]

[[Hepatitis E]]

[[Hepatitis Of Unknown Origin]]

[[Hereditary Elliptocytosis]]  

[[Hereditary Haemorrhagic Telangiectasia]] 

[[Hereditary Motor Sensory Neuropathy]]

Hereditary Polyposis, See [[Familial Polyposis]]

Hereditary Spastic Paraplegia, See [[Central Nervous System Disease]]

[[Hereditary Spherocytosis]]

[[Hernia]]

[[Herpes Simplex Virus]]

Herpes Zoster Virus, See [[Chicken Pox]]

[[Hidradenitis Suppurativa]] 

High Affinity Haemoglobin, See [[Haemoglobin Disorder]]

[[High bilirubin]]

High Cholesterol, See [[Hyperlipidaemia]]

[[High ferritin]]

[[High Risk Sexual Behaviour]]

[[Hip Dislocation]] 

[[Hirschsprung’s Disease]]

[[HIV]]

Hodgkin Lymphoma, See [[Malignancy]]

[[Hormone Replacement Therapy]]

HRT, See [[Hormone Replacement Therapy]]

[[HTLV Infection]]

Hughes Syndrome, See [[Anti-Phospholipid Syndrome]]

Human Bite, See [[Innoculation Injury]]
hy

Human Growth Hormone], See [[Hormone Replacement Therapy]]

Human Immunodeficiency Virus, See [[HIV]]

[[Human Papilloma Virus]]

[[Huntington Disease]]

Hydatidiform Mole, See [[Pregnancy]] 

[[Hydrocephalus]] 

[[Hydronephrosis]] 

[[Hyperaldosteronism]]

Hyperbilirubinaemia, see [[High bilirubin]]

Hypercholesterolaemia, See [[Hyperlipidaemia]]

Hyperferritinaemia, See [[High ferritin]]

[[Hyperlipidaemia]] 

[[Hypermobility Syndrome]] 

[[Hyperparathyroidism]] 

Hyperprolactinaemia, See [[Pituitary Adenoma]] 

[[Hypertension]]

Hyperthyroidism, See [[Thyroid Disease]] 

[[Hypertrophic Obstructive Cardiomyopathy]] 

Hypoadrenalism, See [[Addison Disease]] 

Hypofibrinogenaemia, See [[Bleeding Disorder]]

[[Hypogonadism]] 

[[Hypoparathyroidism]] 

[[Hypopituiarism]]

[[Hypotension]] 

Hypothyroidism, See [[Thyroid Disease]]

Hysterectomy, See [[Surgery]]

==I== 

Ibuprofen, See [[Non Steroidal Anti-Inflammatory Drug]]

[[Idiopathic Intracranial Hypertension]] 

[[IgA Deficiency]]

IgA Nephropathy, See [[Kidney Disease]]

[[Ileostomy]]

Immune Deficiency, See [[Immunosuppression]]

[[Immune Thrombocytopenia]]

[[Immunisation]]

Immunoglobulin Therapy, See [[Transfusion]]

[[Immunosuppression]]

[[Impetigo]] 

In-vitro Fertilisation, Seee [[Hormone Replacement Therapy]]

[[Infection, Acute]]

Infectious Mononucleosis, See [[Epstein-Barr Virus]]

Infective Endocarditis, See [[Endocarditis]]

[[Infertility]] 

[[Inflammatory Bowel Disease]] 

[[Influenza]]

Influenza Vaccination, See [[Immunisation]]

[[Inherited Blood Disorder, first degree relative with]]

[[Injection of Non-Prescription drugs]]

[[Inherited Disease]]

[[Innoculation Injury]] 

Intermittent Claudication, See [[Peripheral Vascular Disease]]

[[Iron Deficiency (Anaemia)]]

[[Irritable Bowel Syndrome]] 

Ischaemic Heart Disease, See [[Heart, Coronary Artery Disease]]

IVF, See [[Hormone Replacement Therapy]]

==J==

[[Jaundice]]

[[Juvenile Idiopathic Arthritis]]

==K==

Kala-Azar, See [[Leishmaniasis]]

[[Kallman Syndrome]] 

[[Kawasaki Disease]] 

Key-Hole Surgery, See [[Surgery]]

[[Kidney Disease]]

Kidney Stones, see [[Kidney Disease]]

Kidney Transplant, See [[Tissue Or Organ Transplant]]

[[Kidney, Single]]

Kienbock Disease, See [[Avascular Necrosis]] 

[[Klinefelter Syndrome]] 

Kyphosis, See [[Back Conditions]]

==L==

[[Labyrinthitis]] 

Laminectomy, See [[Back Conditions]] 

Laparoscopy, See [[Surgery]]

[[Laser Treatment]]

Lassa Fever, See [[Viral Haemorrhagic Fever]]

Latex Allergy, See [[Allergy]]

Left Branch Bundle Block, See [[Heart, Arrhythmia]]

Legionnaire's Disease, See [[Infection, Acute]]

[[Leishmaniasis]]

Leptospirosis See [[Infection, Acute]]

Leukaemia, See [[Malignancy]]

[[Lichen Planus]] 

[[Lichen Sclerosus]] 

[[Lipoma]] 

[[Liver Function, Abnormal]]

Low Blood Pressure, See [[Hypotension]]

Low Ferritin, See [[Iron Deficiency (Anaemia)]]

Low Haemoglobin, See [[Anaemia]]

Low Platelets, See [[Thrombocytopenia]]

Lumbar Spine Abnormality, See [[Back Conditions]]

Lupus, See [[Systemic Lupus Erythematosus]]

[[Lupus Anticoagulant]] 

Lyme Disease, See [[Infection, Acute]]

[[Lymphadenopathy]]

[[Lymphoedema]] 

[[Lymphogranuloma Venereum]]

==M==

[[Macrocytosis]] 

[[Malaria]] 

[[Malignancy]]

[[Malignant Hyperpyrexia]] 

Malignant Melanoma, See [[Malignancy]] 

Manic Depression, See [[Bipolar Affective Disorder]]

Marburg Fever, See [[Viral Haemorrhagic Fever]]

[[Marfan Syndrome]] 

Mastectomy, See [[Surgery]]

Mastoid Operation, See [[Surgery]]

ME, See [[Myalgic Encephalomyelitis]]

Medical Trial, See [[Clinical Trial]]

Membranous Glomerulonephritis, See [[Kidney Disease]]

[[Meniere Disease]]

Meningioma, See [[Brain Tumour]]

Meningitis,  See [[Infection, Acute]]

[[Menopause]]

[[Menorrhagia]]

Metabolic Disease, Seee [[Inherited Disease]]

MGUS, See [[Monoclonal Gammopathy]]

Micropituitary Adenoma, See [[Pituitary Adenoma]] 

[[Migraine]] 

[[Miscarriage]] 

Mitral Regurgitation, See [[Heart, Valve Disease]]

Mitral Stenosis, See [[Heart, Valve Disease]]

Mitral Valve Disease, See [[Heart, Valve Disease]]

Monkeypox, See [[Mpox]]

[[Monoclonal Gammopathy]]  

Mononucleosis, See [[Epstein-Barr Virus]] 

[[Morphoea]] 

Motor Neurone Disease, See [[Central Nervous System Disease]] 

Motor Sensory Neuropathy, See [[Hereditary Motor Sensory Neuropathy]] 

[[Mpox]]

[[MRSA]] 

MS, See [[Multiple Sclerosis]]

[[Multiple Sclerosis]]

[[Muscular Dystrophy]] 

[[Muscular Dystrophy Carrier]] 

[[Myalgic Encephalomyelitis]] 

[[Myasthenia Gravis]] 

[[Myelodysplasia]] 

Myelofibrosis, See [[Myeloproliferative Neoplasm]]

[[Myeloproliferative Neoplasm]]

[[Myocarditis]] 

Myoclonus, See [[Central Nervous System Disease]]

[[Myositis]] 

Myotonia Congenita, See [[Muscular Dystrophy]] 

Myotonic Dystrophy, See [[Muscular Dystrophy]] 

Myxoedema, See [[Thyroid Disease]] 

[[Myxoma]]

==N==

[[Narcolepsy]] 

[[Needle Phobia]]

Needlestick Injury, See [[Innoculation Injury]]

Neotigason, See [[Acne]]

Nephrectomy (Kidney Removal), See [[Kidney, Single]]

Nephritis, See [[Kidney Disease]] 

Nephropathy, See [[Kidney Disease]]

Nephrotic Syndrome, See [[Kidney Disease]] 

[[Neurofibromatosis]]

Neuroma, See [[Brain Tumour]]

[[Neurosurgery]]

[[Neutropenia]] 

[[Non Steroidal Anti-Inflammatory Drug]]

Non-Hodgkin Lymphoma, See [[Malignancy]]

Nose Bleed, See [[Epistaxis]]

NSAID, See [[Non Steroidal Anti-Inflammatory Drug]]

==O==

Obesity, See [[Weight]]

[[Obsessive Compulsive Disorder]] 

[[Obstetric Cholestasis]] 

[[Obstructive Sleep Apnoea]] 

[[Ocular Tissue Recipient]]

Oesophagitis, See [[Gastro-Oesophageal Reflux]] 

[[Onchocerciasis]] 

Operation, See [[Surgery]]

[[Optic Neuritis]] 

[[Osgood-Schlatter Disease]]

Osler-Weber-Rendu Disease, See [[Hereditary Haemorrhagic Telangiectasia]]

[[Osteoarthritis]] 

[[Osteochondroma]]

Osteodystrophia Deformans, See [[Paget Disease]]

[[Osteogenesis Imperfecta]] 

Osteoma, See [[Osteochondroma]]

[[Osteomalacia]]

[[Osteomyelitis]]

[[Osteopenia]] 

[[Osteoporosis]] 

[[Otosclerosis]] 

[[Ovarian Cyst]]

==P==

Pacemaker, See [[Heart, Arrhythmia]]

[[Paget Disease]] 

Paget Disease Of The Nipple, See [[Malignancy]]

[[Pain Medications]] 

[[Palindromic Rheumatism]] 

[[Pancreatitis]] 

Panic Attacks, See Anxiety Disorder

Paraplegia, See [[Disabled Volunteer]]

Paraprotein, See [[Monoclonal Gammopathy]]

[[Paratyphoid Fever]] 

Parkinson Disease, See [[Central Nervous System Disease]]

[[Parvovirus]] 

Patent Ductus Arteriosus, See [[Heart, Congenital Defect]]

Patent Foramen Ovale, See [[Heart, Congenital Defect]]

[[Pectus excavatum ]]

[[Pelvic Inflammatory Disease]]

[[Pemphigoid]] 

[[Pemphigus]] 

[[Peptic Ulcer]] 

[[Pericarditis]] 

[[Peripheral Neuropathy]] 

[[Peripheral Vascular Disease]]

[[Pernicious Anaemia]] 

Peroneal Muscular Atrophy, See [[Hereditary Motor Sensory Neuropathy]] 

[[Perthes Disease]] 

[[Peyronie Disease]] 

Phaeochromocytoma, See [[Malignancy]]

[[Phenylketonuria]] 

[[Phlebitis]] 

[[Pilonidal Sinus]] 

[[Pituitary Adenoma]]

[[Pityriasis]]

[[Pleural Effusion]] 

[[Pleurisy]] 

Pneumonia, See [[Infection, Acute]]

[[Pneumothorax]] 

Polio, See [[Disabled Volunteer]]

Polyarteritis Nodosa, See [[Vasculitis]]

[[Polycystic Ovarian Syndrome]]

[[Polycythaemia]] 

Polycythemia Rubra Vera, See [[Myeloproliferative Neoplasm]]

[[Polymyalgia]] 

[[Porphyria (All Types)]] 

Positive Cervical Smear, See [[Cervical Carcinoma In-Situ]]

[[Post-donation guidelines]]

Post-Viral Fatigue Syndrome, See [[Myalgic Encephalomyelitis]]

[[POTS (Postural Orthostatic Tachycardia Syndrome)]] 

[[Pre-Eclampsia]]

[[Pregnancy]] 

[[Pre-Malignant Conditions]]

[[PrEP/PEP]]

[[Primary Biliary Cholangitis]]

[[Prion-Associated Disease]]

[[Proctitis]] 

Prolactinoma, See [[Pituitary Adenoma]]

Prolapsed Disc, See [[Back Conditions]]

[[Prostate, Enlarged]] 

Prostatism, See [[Benign Prostatic Hyperplasia]]

Protein C Deficiency, See [[Thrombophilia]]

Protein S Deficiency, See [[Thrombophilia]]

[[Proteinuria]]

Prothrombin Gene Mutation, See [[Thrombophilia]]

Psychosis, see [[Schizophrenia]] 

[[Psoriasis]] 

Psoriatic Arthritis, See [[Psoriasis]] 

Pulmonary Embolus, See [[Thrombosis]]

Pulmonary Stenosis / Regurgitation, See [[Heart, Congenital Defect]]

Pulmonary Valvotomy, See [[Heart, Valve Disease]] 

[[Purpura]] 

Pyelonephritis, See [[Kidney Disease]]

[[Pyloric Stenosis]] 

[[Pyruvate Kinase Deficiency]]

==Q==

[[Q Fever]]

==R==

[[Rabies]]

[[Radionuclide Therapy]]

[[Radiotherapy]]

[[Raynaud Disease]] 

[[Reactive Arthritis]]

[[Reactive Hypoglycaemia]]

[[Reflex Sympathetic Dystrophy]] 

Reflux, See [[Gastro-Oesophageal Reflux]]

Reiter Syndrome, See [[Reactive Arthritis]]

Renal Colic, See [[Kidney Disease]]

Renal Disease, See [[Kidney Disease]]

[[Restless Legs Syndrome]] 

[[Retinitis Pigmentosa]]

[[Retinoic Acid Derivatives]]

[[Reye Syndrome]]

[[Rheumatic Fever]] 

[[Rheumatoid Arthritis]] 

[[Rhinitis]] 

Ricketts, See [[Disabled Volunteer]]

[[Rickettsial Infection]]

Right Bundle Branch Block, See [[Heart, Arrhythmia]] 

[[Ringworm]]

River Blindness, See [[Onchocerciasis]]

Roaccutane, See [[Acne]]

Rocky Mountain Spotted Fever, See [[Rickettsial Infection]] 

Rodent Ulcer, See [[Basal Cell Carcinoma]]

[[Rosacea]]

==S==

Sacroiliac Joint Problems, See [[Back Conditions]]

Sandhoff Disease, See [[Inherited Disease]] 

[[Sarcoidosis]] 

[[Scabies]]

[[Scarlet Fever]] 

Scheuermann Disease, See [[Back Conditions]]

[[Schistosomiasis]] 

[[Schizophrenia]]

Schwannoma, See [[Acoustic Neuroma]]

Sciatica, See [[Back Conditions]]

[[Scleroderma]] 

Scoliosis, See [[Back Conditions]]

[[Sebaceous Cyst]]

[[Seborrhoeic Dermatitis]] 

Seizures, See [[Epilepsy]] 

Sepsis, see [[Septicaemia]]

[[Septicaemia]]

[[Septic arthitis]]

Sex Change, See [[Gender Reassignment]]

[[Sexual Orientation]]

Shingles, See [[Chicken Pox]]

Shwachman-Diamond Syndrome, See [[Inherited Disease]]

[[Sickle Cell Disease]] 

[[Sickle Cell Trait]] 

[[Simple Cyst]]

[[Situs Inversus]]

[[Sjogren’s Syndrome]] 

Sleeping Sickness, See [[African Trypanosomiasis]]

Smear - Abnormal Cervical, See [[Cervical Carcinoma In-Situ]]

[[South American Trypanosomiasis]]

Spasmodic Torticollis, See [[Back Conditions]]

Spherocytosis, See [[Hereditary Spherocytosis]]

[[Spina Bifida]]

Spinal Fusion, See [[Back Conditions]] 

Spinal Muscular Atrophy, See [[Inherited Disease]]

Spinal Stenosis, See [[Back Conditions]]

[[Spitz Naevus]]

[[Splenectomy]]

[[Splenomegaly]]

Spondylolisthesis, See [[Back Conditions]]

Spondylosis, See [[Back Conditions]]

Spot Baldness, See [[Alopecia Areata]]

Spots, See [[Acne]]

[[Steroid Treatment]]

[[Stevens-Johnson Syndrome]] 

Stickler Syndrome, See [[Inherited Disease]] 

[[Still Disease]]

Stroke, See [[Cerebrovascular Disease]]

[[Subarachnoid Haemorrhage]] 

[[Subdural Haematoma]]

[[Subglottic Stenosis]]

Superficial Thrombophlebitis, See [[Thrombosis]]

Supraventricular Tachycardia, See [[Heart, Arrhythmia]]

[[Surgery]]

[[Suxamethonium Allergy]] 

Sydenham Chorea, See [[Rheumatic Fever]] 

[[Syphilis]] 

[[Syringomyelia]] 

[[Systemic Lupus Erythematosus]]

==T==

Tachycardia, See [[Heart, Arrhythmia]]

Takayasu Arteritis, See [[Vasculitis]]

Tattoo, See [[Body Piercing]]

Tay Sachs Disease, See [[Inherited Disease]]

Temporal Arteritis, See [[Vasculitis]]

Temporal Lobectomy, See [[Neurosurgery]] and [[Epilepsy]]

Termination Of Pregnancy, See [[Pregnancy]] and [[Surgery]] 

Testosterone Injections, See [[Hormone Replacement Therapy]] and [[Addiction and Drug Abuse]] 

Tetralogy Of Fallot, See [[Heart, Congenital Defect]]

Tetraplegia, See [[Disabled Volunteer]]

Thalassaemia Major, See [[Haemoglobin Disorder]]

Thalassaemia Trait (Minor), See [[Haemoglobin Disorder]]

[[Thoracic Outlet Syndrome]] 

Thrombocythemia, See [[Thrombocytosis]]

[[Thrombocytopenia]] 

[[Thrombocytosis]]

[[Thrombophilia]]

Thrombophlebitis, See [[Thrombosis]]

[[Thrombosis]]

Thrush, See [[Candida Infection]]

[[Thyroid Disease]]

Thyrotoxicosis, See [[Thyroid Disease]]

Tick Typhus, See [[Rickettsial Infection]]

[[Tissue Or Organ Transplant]]

[[Toxoplasmosis]] 

[[Transfusion]]

Transient Ischaemic Attack (TIA), See [[Cerebrovascular Disease]]

Transgender, See [[Considerations for transgender and gender non-binary individuals]]

Treacher-Collins Syndrome, See [[Inherited Disease]]

Trial, See [[Clinical Trial]]

Tricuspid Regurgitation, See [[Heart, Valve Disease]]

Tricuspid Stenosis, See [[Heart, Valve Disease]] 

[[Tropical Viruses]]

[[Tropical viruses ALERTS]]

[[Trigeminal Neuralgia]] 

[[Trying to conceive (TTC)]]

Trypanosoma Cruzi Infection, See [[South American Trypanosomiasis]]

[[Tuberculosis]]

[[Turner Syndrome]] 

[[Typhoid]]

==U==

Ulcerative Colitis, See [[Inflammatory Bowel Disease]]

[[Urticaria]] 

Uterine Fibroid, See [[Fibroids]]

Uveitis, See [[Eye Disease]]

[[Urinary Tract Infection]]

==V== 

Vaccine, See [[Immunisation]]

Vaccination, See [[Immunisation]]

Varicella Zoster, See [[Chicken Pox]]

[[Varicose Veins]] 

[[Vasculitis]] 

[[Vasovagal Attack]] 

[[Venesection]]

Ventricular Septal Defect, See [[Heart, Congenital Defect]] 

Vestibular Schwannoma, See [[Acoustic Neuroma]]

[[Viral Haemorrhagic Fever]]

Visceral Leishmaniasis, See [[Leishmaniasis]]

[[Vitiligo]] 

Von Recklinghausen Disease, See [[Neurofibromatosis]]

Von Willebrand Disease, See [[Bleeding Disorder]]

==W==

Warts, See [[Human Papilloma Virus]]

Wegener Granulomatosis, See [[Vasculitis]] 

[[Weight]] 

[[Weight loss medications]]

Weil Disease, See [[Leptospirosis]]

Werdnig-Hoffmann Disease, See [[Inherited Disease]]

[[West Nile Virus]]

[[Wilson Disease]]

Wolff-Parkinson-White Syndrome, See [[Heart, Arrhythmia]]

==X==

==Y==

[[Yaws]]

[[Yellow Fever]]

Yellow Fever Vaccine, See [[Immunisation]]

==Z==
Zika Virus, See [[Tropical Viruses]]

=Appendix 1 - Haematologic and biochemical testing at donor medical=

'''The following haematological and biochemical tests are performed at the donor medical:'''

FBC 
U&amp;Es (Na, K, Creatinine)
Bone profile (ALP, calcium, phosphate)
Total protein / albumin
Liver function (Bilirubin, ALT, AST, GGT)
Ferritin
Blood glucose
Blood group and antibody screen 
Haemoglobinopathy screen
Clotting – including INR and APTTr 
Pregnancy test (urine or serum) for people of childbearing potential.

=Appendix 2 - Infectious disease marker testing at VT and donor medical=

'''The following infectious disease markers are tested for all donors at the donor medical:'''

HIV (P24 antigen and antibody) + HIV NAT

Hepatitis B (surface antigen and core antibody) + Hepatitis B NAT

Hepatitis C (antibody and RNA) + Hepatitis C NAT

Hepatitis E NAT

HTLV I+II (antibody)

Syphilis (antibody)

Toxoplasma (igG and igM, toxoplasma PCR if igM positive or indeterminate)

EBV (VCA/NA IgG and VCA igM, EBV NAT if igM positive or indeterminate)

CMV (IgG and igM, CMV NAT if CMV igM positive or indeterminate)

Varicella (IgG)


Tropical testing is undertaking according to JPAC guidelines for the relevant country:

https://www.transfusionguidelines.org/dsg/gdri/guidelines

=Appendix 3 - Other investigations at donor medical=

Electrocardiogram (ECG)

Chest X-ray (if indicated according to guidelines)

Urine dipstick +/- ACR +/- MCS

=Appendix 4 - Special consideration for donors in the Armed Forces=

'''Guidance for Armed Forces donors'''

It is recognised that members of the Armed Forces will need to get permission from the Commanding Officer prior to donation. Certain occupations within the MOD, such as aircrew within the RAF, will not allow donation by bone marrow harvest unless it is to a family member, although peripheral blood stem cell donation is permitted.

As a consequence, members of the Armed Forces are permitted to join the register as ‘PBSC only’ if there are concerns about the impact of bone marrow harvest on their ability to fulfil their role, or concerns about possible impact on their career.</text>
      <sha1>ohem7hjxns3yy3u7sf94l3cq742nuay</sha1>
    </revision>
  </page>
</mediawiki>