Anthony Nolan Medical Guidelines - User contributions [en]

Heart, Arrhythmia

2014-09-10T14:11:25Z

AnneliesB: /* Acceptable */

==Acceptability at Recruitment==
QUALIFIED

==Acceptability at CT / Work-Up==
QUALIFIED

==Individual at Risk==
Donor

==Explanation of Condition==
Abnormal heart rhythm or electrical activity. Usually picked up using an electrocardiogram (ECG).

==Guidance==
Possible procedural risk, particularly with general anaesthetic and insertion of central venous catheters. Discuss with MO.

===Acceptable===
Benign atrial or ventricular ectopics (extrasystoles)

Sinus tachycardia/bradycardia acceptable, but inform anaesthetist at work-up if for bone marrow harvest.

Beta-blockers prescribed for benign ectopics or sinus tachycardia are acceptable.

Supraventricular tachycardias (SVT), including atrial fibrillation/flutter, acceptable if successfully treated with catheter ablation and off rate/rhythm-control medications (such as beta-blockers) for at least six months.

Right bundle branch block in the absence of any other abnormality

Left or right sided axis in the absence of any other abnormality

First degree heart block may be acceptable at work up at the discretion of the assessing physician

===Unacceptable===
Uncorrected atrial fibrillation/flutter

Any history of ventricular tachycardia/fibrillation

Wolff-Parkinson-White/Lown-Ganong-Levine syndromes unacceptable unless treated with catheter ablation, and no ECG evidence of accessory pathways.

Second or third degree heart block

All pacemakers and implantable cardiac defibrillators (ICD)

Left bundle branch block

Long-QT syndrome, Brugada syndrome or any other known cause of sudden cardiac death

==Pseudonyms or Related Conditions==
SVT

Atrial fibrillation

Atrial flutter

Tachycardia

Bradycardia

Heart block

Rhythm abnormality

Cardiogenic syncope

Long-QT syndrome

Brugada Syndrome

Wolff-Parkinson-White Syndrome

Lown-Ganong-Levine Syndrome

Re-entrant Tachycardia

Ventricular Tachycardia

==Version==
Version 1, Edition 1

====Date of Last Update====
15th June 2012

Diabetes Mellitus

2014-08-20T10:41:39Z

AnneliesB: /* Guidance */

==Acceptability at Recruitment==
QUALIFIED

==Acceptability at CT / Work-Up==
QUALIFIED

==Individual at Risk==
Donor / Recipient

==Explanation of Condition==
Failure of the body to regulate sugar entry into cells that need it. Caused either by failure of insulin production in the pancreas (type 1 diabetes) or insulin resistance (tyoe 2 diabetes).

==Guidance==
Acceptable if diet controlled only at recruitment. Not acceptable if on anti-diabetic tablets or insulin injections at recruitment.
May be acceptable at CT stage if diabetes is well controlled on anti-diabetic tablets. Discuss each case with Medical Officer.

==Pseudonyms or Related Conditions==
Type 1 Diabetes

Type 2 Diabetes

Non-Insulin Dependent Diabetes Mellitus (NIDDM)
==Version==
Version 1, Edition 1

====Date of Last Update====
15th June 2012

Bipolar Affective Disorder

2013-11-01T13:05:40Z

AnneliesB: /* Guidance */

==Acceptability at Recruitment==
QUALIFIED

==Acceptability at CT / Work-Up==
QUALIFIED

==Individual at Risk==
Donor

==Explanation of Condition==
Psychiatric disorder characterised by alternating phases of hyperactive behaviour (mania) and severe depression.

==Guidance==
May be acceptable if not currently manic, or if condition adequately treated with medication or counseling. Disease must be stable for at least one year.
In addition, if donor is taking valproate or carbamazepine, it should be established that medication is well tolerated, with no significant effect on blood counts and liver function.
Donors taking lithium may donate by bone marrow only.

Ask the following questions:

Can the donor work and travel?
Could the donor cope with a hospital stay if required to donate?
Could the donor cope with pressures involved with donating, as donation may be a stressful procedure for some individuals?

If the answer to these questions are yes, than accept.

Refer to medical officer if necessary.

==Pseudonyms or Related Conditions==
Manic Depression

Manic Depressive Disorder

Bipolar Disorder

==Version==
Version 1, Edition 1

====Date of Last Update====
15th June 2012

Thrombosis

2013-11-01T13:01:46Z

AnneliesB: /* Guidance */

==Acceptability at Recruitment==
QUALIFIED

==Acceptability at CT / Work-Up==
QUALIFIED

==Individual at Risk==
Donor

==Explanation of Condition==
Blood clot in a blood vessel, usually a deep vein of the leg, although the arm or any other part of the body may be affected. Can be provoked (for example after a long haul flight) or unprovoked. Occasionally a clot will become dislodged and travel to the lungs, via the heart, which may be life-threatening (pulmonary embolism).

See also [http://en.wikipedia.org/wiki/Thrombosis Thrombosis]

==Guidance==
Acceptable if a single deep vein thrombosis in the leg, the donor has been fully evaluated to exclude an underlying disease and the donor has completed the required course of anticoagulant therapy. Otherwise defer.

====Unacceptable====
More than one deep vein thrombosis in upper or lower extremities;

A single episode of atypical venous thrombosis, such as portal or mesenteric vein thrombosis;

A single pulmonary embolus, regardless of severity;

Coronary artery thrombosis, with or without underlying atherosclerosis;

Currently on anticoagulant therapy;

Axillary vein thrombosis with evidence of compromised venous return (arm oedema, dilated superficial venous system);

Any episode of arterial thrombosis;

Single unprovoked DVT;

====Acceptable====
A single provoked deep vein thrombosis in upper or lower extremities, and is at least seven days from completion of anticoagulant therapy;

Retinal vein thrombosis;

Superficial thrombophlebitis;

See also [[Thrombophilia]] if identified.

==Pseudonyms or Related Conditions==
Blood Clot or Clots

Deep vein thrombosis

DVT

Pulmonary embolus

Pulmonary embolism

PE

Arterial thrombosis

==Version==
Version 1, Edition 1

====Date of Last Update====
15th June 2012

Bipolar Affective Disorder

2013-11-01T12:42:17Z

AnneliesB: /* Guidance */

==Acceptability at Recruitment==
QUALIFIED

==Acceptability at CT / Work-Up==
QUALIFIED

==Individual at Risk==
Donor

==Explanation of Condition==
Psychiatric disorder characterised by alternating phases of hyperactive behaviour (mania) and severe depression.

==Guidance==
May be acceptable if not currently manic, or if condition adequately treated with medication or counselling. Disease must be stable for at least one year.
In addition, if donor is taking valproate or carbamazepine, it should be establised that medication is well tolerated, with no significant effect on blood counts and liver function.
Donors taking lithium may donate by bone marrow only.

Ask the following questions:

Can the donor work and travel?
Could the donor cope with a hospital stay if required to donate?
Could the donor cope with pressures involved with donating, as donation may be a stressful procedure for some individuals?

If the answer to these questions are yes, than accept.

Refer to medical officer if necessary.

==Pseudonyms or Related Conditions==
Manic Depression

Manic Depressive Disorder

Bipolar Disorder

==Version==
Version 1, Edition 1

====Date of Last Update====
15th June 2012

Asthma

2013-11-01T12:11:42Z

AnneliesB: /* Guidance */

==Acceptability at Recruitment==
QUALIFIED

==Acceptability at CT / Work-Up==
QUALIFIED

==Individual at Risk==
Donor

==Explanation of Condition==
Constriction of the airways which may be triggered by external stimuli (such as cold air, pollen or pollution) or may be spontaneous. Usually controlled by a combination of bronchodilator inhalers (such as salbutamol) and steroid inhalers (such as beclometasone). More severe asthma may require tablet therapy such as theophylline, montelukast or steroids.

Asthmatics are at a higher risk from donation, and from general anaesthetic in particular.

==Guidance==
Acceptable if on any combination of inhalers alone, and asthma is well-controlled.

Not acceptable if asthma is pooly controlled.

Not acceptable if requiring montelukast, theophylline or oral corticosteroids.

Not acceptable if admitted to hospital with need for IV steroids or emergency care in the past 2 years.

Not acceptable if ever been admitted to intensive care due to an asthma attack.

==Pseudonyms or Related Conditions==
Bronchospasm

==Version==
Version 1, Edition 1

====Date of Last Update====
15th June 2012

Thrombosis

2013-11-01T12:04:42Z

AnneliesB: /* Explanation of Condition */

==Acceptability at Recruitment==
QUALIFIED

==Acceptability at CT / Work-Up==
QUALIFIED

==Individual at Risk==
Donor

==Explanation of Condition==
Blood clot in a blood vessel, usually a deep vein of the leg, although the arm or any other part of the body may be affected. Can be provoked (for example after a long haul flight) or unprovoked. Occasionally a clot will become dislodged and travel to the lungs, via the heart, which may be life-threatening (pulmonary embolism).

See also [http://en.wikipedia.org/wiki/Thrombosis Thrombosis]

==Guidance==
====Unacceptable====
More than one deep vein thrombosis in upper or lower extremities;

A single episode of atypical venous thrombosis, such as portal or mesenteric vein thrombosis;

A single pulmonary embolus, regardless of severity;

Coronary artery thrombosis, with or without underlying atherosclerosis;

Currently on anticoagulant therapy;

Axillary vein thrombosis with evidence of compromised venous return (arm oedema, dilated superficial venous system);

Any episode of arterial thrombosis;

Single unprovoked DVT;

====Acceptable====
A single provoked deep vein thrombosis in upper or lower extremities, and is at least seven days from completion of anticoagulant therapy;

Retinal vein thrombosis;

Superficial thrombophlebitis;

See also [[Thrombophilia]] if identified.

==Pseudonyms or Related Conditions==
Blood Clot or Clots

Deep vein thrombosis

DVT

Pulmonary embolus

Pulmonary embolism

PE

Arterial thrombosis

==Version==
Version 1, Edition 1

====Date of Last Update====
15th June 2012

Thrombosis

2013-11-01T12:03:11Z

AnneliesB: /* Unacceptable */

==Acceptability at Recruitment==
QUALIFIED

==Acceptability at CT / Work-Up==
QUALIFIED

==Individual at Risk==
Donor

==Explanation of Condition==
Blood clot in a blood vessel, usually a deep vein of the leg, although the arm or any other part of the body may be affected. Occasionally a clot will become dislodged and travel to the lungs, via the heart, which may be life-threatening (pulmonary embolism).

See also [http://en.wikipedia.org/wiki/Thrombosis Thrombosis]

==Guidance==
====Unacceptable====
More than one deep vein thrombosis in upper or lower extremities;

A single episode of atypical venous thrombosis, such as portal or mesenteric vein thrombosis;

A single pulmonary embolus, regardless of severity;

Coronary artery thrombosis, with or without underlying atherosclerosis;

Currently on anticoagulant therapy;

Axillary vein thrombosis with evidence of compromised venous return (arm oedema, dilated superficial venous system);

Any episode of arterial thrombosis;

Single unprovoked DVT;

====Acceptable====
A single provoked deep vein thrombosis in upper or lower extremities, and is at least seven days from completion of anticoagulant therapy;

Retinal vein thrombosis;

Superficial thrombophlebitis;

See also [[Thrombophilia]] if identified.

==Pseudonyms or Related Conditions==
Blood Clot or Clots

Deep vein thrombosis

DVT

Pulmonary embolus

Pulmonary embolism

PE

Arterial thrombosis

==Version==
Version 1, Edition 1

====Date of Last Update====
15th June 2012

Thrombosis

2013-11-01T12:02:28Z

AnneliesB: /* Explanation of Condition */

==Acceptability at Recruitment==
QUALIFIED

==Acceptability at CT / Work-Up==
QUALIFIED

==Individual at Risk==
Donor

==Explanation of Condition==
Blood clot in a blood vessel, usually a deep vein of the leg, although the arm or any other part of the body may be affected. Occasionally a clot will become dislodged and travel to the lungs, via the heart, which may be life-threatening (pulmonary embolism).

See also [http://en.wikipedia.org/wiki/Thrombosis Thrombosis]

==Guidance==
====Unacceptable====
More than one deep vein thrombosis in upper or lower extremities;

A single episode of atypical venous thrombosis, such as portal or mesenteric vein thrombosis;

A single pulmonary embolus, regardless of severity;

Coronary artery thrombosis, with or without underlying atherosclerosis;

Currently on anticoagulant therapy;

Axillary vein thrombosis with evidence of compromised venous return (arm oedema, dilated superficial venous system);

Any episode of arterial thrombosis;

====Acceptable====
A single provoked deep vein thrombosis in upper or lower extremities, and is at least seven days from completion of anticoagulant therapy;

Retinal vein thrombosis;

Superficial thrombophlebitis;

See also [[Thrombophilia]] if identified.

==Pseudonyms or Related Conditions==
Blood Clot or Clots

Deep vein thrombosis

DVT

Pulmonary embolus

Pulmonary embolism

PE

Arterial thrombosis

==Version==
Version 1, Edition 1

====Date of Last Update====
15th June 2012

Thrombosis

2013-11-01T12:01:12Z

AnneliesB: /* Acceptable */

==Acceptability at Recruitment==
QUALIFIED

==Acceptability at CT / Work-Up==
QUALIFIED

==Individual at Risk==
Donor

==Explanation of Condition==
Blood clot in a blood vessel, usually a deep vein of the leg, although the arm or any other part of the body may be affected. Occasionally a clot will become dislodged and travel to the lungs, via the heart, which may be life-threatening (pulmonary embolism).

See also [http://en.wikipedia.org/wiki/Thrombosis Thrombosis]

==Guidance==
====Unacceptable====
More than one deep vein thrombosis in upper or lower extremities;

A single episode of atypical venous thrombosis, such as portal or mesenteric vein thrombosis;

A single pulmonary embolus, regardless of severity;

Coronary artery thrombosis, with or without underlying atherosclerosis;

Currently on anticoagulant therapy;

Axillary vein thrombosis with evidence of compromised venous return (arm oedema, dilated superficial venous system);

Any episode of arterial thrombosis;

====Acceptable====
A single provoked deep vein thrombosis in upper or lower extremities, and is at least seven days from completion of anticoagulant therapy;

Retinal vein thrombosis;

Superficial thrombophlebitis;

See also [[Thrombophilia]] if identified.

==Pseudonyms or Related Conditions==
Blood Clot or Clots

Deep vein thrombosis

DVT

Pulmonary embolus

Pulmonary embolism

PE

Arterial thrombosis

==Version==
Version 1, Edition 1

====Date of Last Update====
15th June 2012

Inflammatory Bowel Disease

2013-11-01T11:53:35Z

AnneliesB: /* Guidance */

==Acceptability at Recruitment==
NOT ACCEPTABLE

==Acceptability at CT / Work-Up==
Discuss each case with Medical Officer. May be acceptable for BM only if only one episode with complete recovery.

==Individual at Risk==
Donor / Recipient

==Explanation of Condition==
Autoimmune condition leading to chronic, relapsing episodes of diarrhoea and bleeding. Treatment includes aspirin-derived medications, steroids and immunosuppression. Severely affected individuals may require surgical removal of parts of the bowel, and there is an increased risk of bowel cancer in sufferers of ulcerative colitis.

==Guidance==
Discuss with Medical Officer. Risk of donor-acquired autoimmunity in recipient.

==Pseudonyms or Related Conditions==
Crohns disease

Ulcerative Colitis

==Version==
Version 1, Edition 1

====Date of Last Update====
15th June 2012

Inflammatory Bowel Disease

2013-11-01T11:53:09Z

AnneliesB: /* Guidance */

==Acceptability at Recruitment==
NOT ACCEPTABLE

==Acceptability at CT / Work-Up==
Discuss each case with Medical Officer. May be acceptable for BM only if only one episode with complete recovery.

==Individual at Risk==
Donor / Recipient

==Explanation of Condition==
Autoimmune condition leading to chronic, relapsing episodes of diarrhoea and bleeding. Treatment includes aspirin-derived medications, steroids and immunosuppression. Severely affected individuals may require surgical removal of parts of the bowel, and there is an increased risk of bowel cancer in sufferers of ulcerative colitis.

==Guidance==
Discuss with Medical Officer. Risk of donor-acquired autoimmunity in recipient with unacceptable symptoms possible.

==Pseudonyms or Related Conditions==
Crohns disease

Ulcerative Colitis

==Version==
Version 1, Edition 1

====Date of Last Update====
15th June 2012

Inflammatory Bowel Disease

2013-11-01T11:52:21Z

AnneliesB: /* Acceptability at CT / Work-Up */

==Acceptability at Recruitment==
NOT ACCEPTABLE

==Acceptability at CT / Work-Up==
Discuss each case with Medical Officer. May be acceptable for BM only if only one episode with complete recovery.

==Individual at Risk==
Donor / Recipient

==Explanation of Condition==
Autoimmune condition leading to chronic, relapsing episodes of diarrhoea and bleeding. Treatment includes aspirin-derived medications, steroids and immunosuppression. Severely affected individuals may require surgical removal of parts of the bowel, and there is an increased risk of bowel cancer in sufferers of ulcerative colitis.

==Guidance==
Unacceptable. Risk of donor-acquired autoimmunity in recipient with unacceptable symptoms.

==Pseudonyms or Related Conditions==
Crohns disease

Ulcerative Colitis

==Version==
Version 1, Edition 1

====Date of Last Update====
15th June 2012

Epilepsy

2013-11-01T11:47:36Z

AnneliesB: /* Guidance */

==Acceptability at Recruitment==
QUALIFIED

==Acceptability at CT / Work-Up==
QUALIFIED

==Individual at Risk==
Donor

==Explanation of Condition==
Seizures caused by abnormal electrical activity in the brain. These can be secondary (e.g. as a result of a brain injury), or primary, where a precipitating cause is not found.

==Guidance==
Unacceptable if has had an epileptic event in the last year or if there is an underlying organic pathology. Otherwise acceptable.

==Pseudonyms or Related Conditions==
Seizures

==Version==
Version 1, Edition 1

====Date of Last Update====
15th June 2012

Heart, Arrhythmia

2013-11-01T11:43:44Z

AnneliesB: /* Unacceptable */

==Acceptability at Recruitment==
QUALIFIED

==Acceptability at CT / Work-Up==
QUALIFIED

==Individual at Risk==
Donor

==Explanation of Condition==
Abnormal heart rhythm or electrical activity. Usually picked up using an electrocardiogram (ECG).

==Guidance==
Possible procedural risk, particularly with general anaesthetic and insertion of central venous catheters. Discuss with MO.

===Acceptable===
Benign atrial or ventricular ectopics (extrasystoles)

Sinus tachycardia/bradycardia acceptable, but inform anaesthetist at work-up if for bone marrow harvest.

Beta-blockers prescribed for benign ectopics or sinus tachycardia are acceptable.

Supraventricular tachycardias (SVT), including atrial fibrillation/flutter, acceptable if successfully treated with catheter ablation and off rate/rhythm-control medications (such as beta-blockers) for at least six months.

Right bundle branch block in the absence of any other abnormality

First degree heart block may be acceptable at work up at the discretion of the assessing physician

===Unacceptable===
Uncorrected atrial fibrillation/flutter

Any history of ventricular tachycardia/fibrillation

Wolff-Parkinson-White/Lown-Ganong-Levine syndromes unacceptable unless treated with catheter ablation, and no ECG evidence of accessory pathways.

Second or third degree heart block

All pacemakers and implantable cardiac defibrillators (ICD)

Left bundle branch block

Long-QT syndrome, Brugada syndrome or any other known cause of sudden cardiac death

==Pseudonyms or Related Conditions==
SVT

Atrial fibrillation

Atrial flutter

Tachycardia

Bradycardia

Heart block

Rhythm abnormality

Cardiogenic syncope

Long-QT syndrome

Brugada Syndrome

Wolff-Parkinson-White Syndrome

Lown-Ganong-Levine Syndrome

Re-entrant Tachycardia

Ventricular Tachycardia

==Version==
Version 1, Edition 1

====Date of Last Update====
15th June 2012

Heart, Arrhythmia

2013-11-01T11:43:14Z

AnneliesB: /* Acceptable */

==Acceptability at Recruitment==
QUALIFIED

==Acceptability at CT / Work-Up==
QUALIFIED

==Individual at Risk==
Donor

==Explanation of Condition==
Abnormal heart rhythm or electrical activity. Usually picked up using an electrocardiogram (ECG).

==Guidance==
Possible procedural risk, particularly with general anaesthetic and insertion of central venous catheters. Discuss with MO.

===Acceptable===
Benign atrial or ventricular ectopics (extrasystoles)

Sinus tachycardia/bradycardia acceptable, but inform anaesthetist at work-up if for bone marrow harvest.

Beta-blockers prescribed for benign ectopics or sinus tachycardia are acceptable.

Supraventricular tachycardias (SVT), including atrial fibrillation/flutter, acceptable if successfully treated with catheter ablation and off rate/rhythm-control medications (such as beta-blockers) for at least six months.

Right bundle branch block in the absence of any other abnormality

First degree heart block may be acceptable at work up at the discretion of the assessing physician

===Unacceptable===
Uncorrected atrial fibrillation/flutter

Any history of ventricular tachycardia/fibrillation

Wolff-Parkinson-White/Lown-Ganong-Levine syndromes unacceptable unless treated with catheter ablation, and no ECG evidence of accessory pathways.

Any degree of heart block

All pacemakers and implantable cardiac defibrillators (ICD)

Left bundle branch block

Long-QT syndrome, Brugada syndrome or any other known cause of sudden cardiac death

==Pseudonyms or Related Conditions==
SVT

Atrial fibrillation

Atrial flutter

Tachycardia

Bradycardia

Heart block

Rhythm abnormality

Cardiogenic syncope

Long-QT syndrome

Brugada Syndrome

Wolff-Parkinson-White Syndrome

Lown-Ganong-Levine Syndrome

Re-entrant Tachycardia

Ventricular Tachycardia

==Version==
Version 1, Edition 1

====Date of Last Update====
15th June 2012

Epilepsy

2013-10-29T11:26:38Z

AnneliesB: /* Guidance */

==Acceptability at Recruitment==
QUALIFIED

==Acceptability at CT / Work-Up==
QUALIFIED

==Individual at Risk==
Donor

==Explanation of Condition==
Seizures caused by abnormal electrical activity in the brain. These can be secondary (e.g. as a result of a brain injury), or primary, where a precipitating cause is not found.

==Guidance==
Unacceptable if has had an epileptic event or required anti-epileptic medication in the last year. Otherwise acceptable

==Pseudonyms or Related Conditions==
Seizures

==Version==
Version 1, Edition 1

====Date of Last Update====
15th June 2012

Epilepsy

2013-10-29T11:26:19Z

AnneliesB: Removed protection from "Epilepsy"

==Acceptability at Recruitment==
QUALIFIED

==Acceptability at CT / Work-Up==
QUALIFIED

==Individual at Risk==
Donor

==Explanation of Condition==
Seizures caused by abnormal electrical activity in the brain. These can be secondary (e.g. as a result of a brain injury), or primary, where a precipitating cause is not found.

==Guidance==
Unacceptable if has had an epileptic event or required anti-epileptic medication in the last three years. Otherwise acceptable

==Pseudonyms or Related Conditions==
Seizures

==Version==
Version 1, Edition 1

====Date of Last Update====
15th June 2012

G6PD Deficiency

2013-08-16T13:42:10Z

AnneliesB: /* Guidance */

==Acceptability at Recruitment==
NOT ACCEPTABLE

==Acceptability at CT / Work-Up==
QUALIFIED

==Individual at Risk==
Donor

==Explanation of Condition==
Deficiency of an enzyme important in providing energy to cells, particularly red blood cells. Sufferers are prone to breakdown of red blood cells when exposed to certain drugs or other physiological stresses.

==Guidance==
Discuss with Medical Officer. Unacceptable if severe. If mild may donate but discuss with anaesthetist and inform transplant centre.

==Pseudonyms or Related Conditions==
Glucose-6-Phosphate Deficiency

==Version==
Version 1, Edition 1

====Date of Last Update====
15th June 2012

G6PD Deficiency

2013-08-16T13:40:26Z

AnneliesB: /* Acceptability at Recruitment */

==Acceptability at Recruitment==
NOT ACCEPTABLE

==Acceptability at CT / Work-Up==
QUALIFIED

==Individual at Risk==
Donor

==Explanation of Condition==
Deficiency of an enzyme important in providing energy to cells, particularly red blood cells. Sufferers are prone to breakdown of red blood cells when exposed to certain drugs or other physiological stresses.

==Guidance==
Unacceptable if severe. If mild may donate but discuss with anaesthetist and inform transplant centre.

==Pseudonyms or Related Conditions==
Glucose-6-Phosphate Deficiency

==Version==
Version 1, Edition 1

====Date of Last Update====
15th June 2012

G6PD Deficiency

2013-08-16T13:32:37Z

AnneliesB: /* Acceptability at Recruitment */

==Acceptability at Recruitment==

==Acceptability at CT / Work-Up==
QUALIFIED

==Individual at Risk==
Donor

==Explanation of Condition==
Deficiency of an enzyme important in providing energy to cells, particularly red blood cells. Sufferers are prone to breakdown of red blood cells when exposed to certain drugs or other physiological stresses.

==Guidance==
Unacceptable if severe. If mild may donate but discuss with anaesthetist and inform transplant centre.

==Pseudonyms or Related Conditions==
Glucose-6-Phosphate Deficiency

==Version==
Version 1, Edition 1

====Date of Last Update====
15th June 2012

G6PD Deficiency

2013-08-16T13:32:13Z

AnneliesB: /* Acceptability at Recruitment */

==Acceptability at Recruitment==
No

==Acceptability at CT / Work-Up==
QUALIFIED

==Individual at Risk==
Donor

==Explanation of Condition==
Deficiency of an enzyme important in providing energy to cells, particularly red blood cells. Sufferers are prone to breakdown of red blood cells when exposed to certain drugs or other physiological stresses.

==Guidance==
Unacceptable if severe. If mild may donate but discuss with anaesthetist and inform transplant centre.

==Pseudonyms or Related Conditions==
Glucose-6-Phosphate Deficiency

==Version==
Version 1, Edition 1

====Date of Last Update====
15th June 2012

Main Page

2013-08-07T11:15:28Z

AnneliesB: /* D */

=About the Anthony Nolan Medical and Lifestyle Guidelines=

For potential and current donors, please note that these guidelines are primarily intended for use by Anthony Nolan staff.

The Anthony Nolan Medical and Lifestyle Guidelines are put in place to ensure the safety of both our stem cell donors and the recipients of their donations.

Because of the volunteer nature of stem cell donation, we have a responsibility to ensure that our donors are able to donate safely, with minimal risk to their own health. For this reason, our medical criteria are strict, and considerably more strict than medical criteria for having a procedure, such as an operation, for the benefit of your own health.

Some donor medical conditions present a risk to the '''recipient''' of the donation. In these cases, we may allow a donor to donate because the benefit for the patient of receiving the transplant outweighs the risk.

=Guidance for Recruiters=

The list is not exhaustive; therefore, particular cases may require further clarification by our Medical Officer.

IN SUCH CASES PLEASE NOTE THE FOLLOWING:
The volunteer should be asked to complete an application form giving full details of their
medical status ensuring that the following information is given:

*Name of medical condition.
*Date of diagnosis.
*Name of medication(s) taken.
*Length of time medication has been taken.
*Is the medication seen as a short course or long-term prescription?
*Does the volunteer have any limitations to life-style?
*Is the volunteer’s condition regularly assessed by GP/Consultant?

Once the application has been reviewed the donor will be contacted and informed
of the decision.

This list is in place to help us recruit medically eligible volunteer blood stem cell donors.
We have a duty to ensure that volunteer donors are put at minimal risk whilst also considering the safety and outcome for transplant recipients.

The criteria, which we use to assess the suitability of a volunteer to donate, are considerably
more stringent than those taken into consideration for volunteers undergoing a procedure for
their own medical health status.

If you have any queries please contact The Anthony Nolan Donor Support Team
as follows:

Telephone 0303 303 0303 (9am – 5pm) and ask for The Donor Support Team or
E-mail: info@anthonynolan.org

=Recently Updated Guidance=

'''24/10/12. Guidance Added:''' [[Breast Feeding]]

'''04/01/13. Guidance updated:''' [[Weight]]

'''02/05/14. Guidance updated:''' [[Retinoic Acid Derivatives]]

=Multiple Medical Conditions=

Some donors will have more than one medical problem, and the potential combinations are too numerous to list in this guidance. Some combinations of conditions will increase the risk of donor harm, despite being acceptable in isolation.

For example, hypertension, smoking, high cholesterol and diet-controlled diabetes may all be acceptable, but this combination in an older donor would considerably increase their risk of a heart attack or stroke.

If in doubt, please discuss these donors with the medical officer.

=Index of Conditions=

==A==

Accident, See [[Fracture]] and/or [[Surgery]]

[[Acetylcholinesterase Deficiency]]

[[Achondroplasia]]

Acitretin, See [[Acne]]

[[Acne]]

[[Acoustic Neuroma]]

Acoustic Schwannoma, See [[Acoustic Neuroma]]

[[Acromegaly]]

[[Actinic Prurigo]]

[[Acupuncture]]

ADD, See [[Attention Deficit Hyperactivity Disorder]]

[[Addiction and Drug Abuse]]

[[Addison Disease]]

Adenocarcinoma, See [[Malignancy]]

[[Adenoma]]

ADHD, See [[Attention Deficit Hyperactivity Disorder]]

Adrenal Hyperplasia, See [[Congenital Adrenal Hyperplasia]]

[[African Trypanosomiasis]]

AIDS, See [[HIV]]

[[Albino]]

[[Alcohol Intake]]

[[Allergy]]

[[Alopecia]]

[[Alpha 1 Antitrypsin Deficiency]]

[[Alpha Mannosidosis]]

[[Alports Syndrome]]

Anabolic Steroids, See [[Addiction and Drug Abuse]]

[[Anaemia]]

[[Anaesthetic Complications]]

Angina, See [[Heart, Coronary Artery Disease]]

[[Animal Bite]]

[[Ankylosing Spondylitis]]

Anthrax Vaccine, See [[Immunisation]]

Anti-Inflammatory Drug, See [[Non Steroidal Anti-Inflammatory Drug]]

[[Anti-Phospholipid Syndrome]]

[[Antibiotic Treatment]]

[[Antibodies]]

[[Anticoagulants]]

Anticonvulsants, See [[Epilepsy]]

Antithrombin Deficiency, See [[Thrombophilia]]

[[Anxiety Disorder]]

Aortic Regurgitation, See [[Heart, Valve Disease]]

Aortic Stenosis, See [[Heart, Valve Disease]]

Aortic Valve Disease, See [[Heart, Valve Disease]]

[[Arachnoid Cyst]]

[[Arnold-Chiari Syndrome]]

Arrhythmia, See [[Heart, Arrhythmia]]

[[Arthrogryposis]]

Arthroscopy, See [[Surgery]]

[[Asperger Syndrome]]

Aspirin, See [[Non Steroidal Anti-Inflammatory Drug]]

[[Asthma]]

Atherosclerosis, See [[Heart, Coronary Artery Disease]]

Atrial Fibrillation, See [[Heart, Arrhythmia]]

Atrial Myxoma, See [[Myxoma]]

Atrial Septal Defect (ASD), See [[Heart, Congenital Defect]]

[[Attention Deficit Hyperactivity Disorder]]

[[Avascular Necrosis]]

Avodart, See [[Dutasteride]]

Avulsion Fracture (Other Than Spinal), See [[Fracture]]

Avulsion Fracture (Spinal), See [[Back Conditions]]

==B==

[[B12 Deficiency]]

[[Babesiosis]]

[[Back Conditions]]

[[Balanitis Xerotica Obliterans (BXO)]]

[[Basal Cell Carcinoma]]

BCG Vaccination, See [[Immunisation]]

[[Bells Palsy]]

Benign Essential Tremor, See [[Essential Tremor]]

Benign Ethnic Neutropenia, See [[Neutropenia]]

Benign Intracranial Hypertension, See [[Idiopathic Intracranial Hypertension]]

[[Benign Positional Vertigo]]

[[Benign Prostatic Hyperplasia]]

Berger Disease, See [[Kidney Disease]]

Beta Blockers, See [[Medications]]

Beta Thalassemia, See [[Haemoglobin Disorder]]

Bilateral Scleritis, See [[Eye Disease]]

Bilharzia, See [[Schistosomiasis]]

[[Bipolar Affective Disorder]]

Bisexual, See [[Sexual Orientation]]

[[Bleeding Disorder]]

Blocked Artery (Heart), See [[Heart, Coronary Artery Disease]]

Blood Clot, See [[Thrombosis]]

Blood Pressure, See [[Hypertension]]

Blood Transfusion, See [[Transfusion]]

[[Body Piercing]]

Bone Density (Abnormal), See [[Osteoporosis]]

Bone Graft, See [[Surgery]] and/or [[Back Conditions]]

Borreliosis, See [[Lyme Disease]]

Bowens Disease, See [[Malignancy]]

BPH, See [[Benign Prostatic Hyperplasia]]

Brain Surgery, See [[Neurosurgery]]

[[Brain Tumour]]

[[Breast Augmentation (Implants)]]

[[Breast Feeding]]

[[Bronchiectasis]]

Bronchitis, See [[Infection, Acute]]

Brown-Sequard Syndrome, See [[Central Nervous System Disease]]

[[Brucellosis]]

[[Bursitis]]

==C==

[[C1 Esterase Inhibitor Deficiency]]

Cancer, See [[Malignancy]]

[[Candida Infection]]

Candidiasis, See [[Candida Infection]]

Carcinoid Syndrome, See [[Malignancy]]

Cardiac Failure, See [[Heart, Muscle Disease]]

Cardiac Syndrome X, See [[Heart, Coronary Artery Disease]]

Cardiomegaly, See [[Heart, Muscle Disease]]

Cardiomyopathy, See [[Heart, Muscle Disease]]

[[Carpal Tunnel Syndrome]]

Cat-Scratch Fever, See [[Infection, Acute]]

[[Causalgia]]

Cellulitis, See [[Infection, Acute]]

[[Central Nervous System Disease]]

Cerebral Malaria, See [[Malaria]]

[[Cerebral Palsy]]

[[Cerebroretinal Angiomatosis]]

Cerebrovascular Accident, See [[Stroke]]

[[Cervical Carcinoma In-Situ]]

Cervical Smear, See [[Cervical Carcinoma In-Situ]]

Cervical Spondylosis, See [[Back Conditions]]

Chagas Disease, See [[South American Trypanosomiasis]]

Charcot Marie Tooth Syndrome, See [[Hereditary Motor Sensory Neuropathy]]

[[Chicken Pox]]

Chlamydia, See [[Infection, Acute]]

Cholecystectomy, See [[Surgery]]

Cholecystitis, See [[Gall-Bladder Disease]]

[[Chondromalacia Patellae]]

Christmas Disease, See [[Bleeding Disorder]]

Chronic Fatigue Syndrome, See [[Myalgic Encephalomyelitis]]

[[Chronic Obstructive Pulmonary Disease]]

[[Cirrhosis]]

CJD, See [[Prion-Associated Disease]]

Clap, See [[Gonorrhoea]]

[[Clinical Trial]]

[[Cluster Headache]]

Coagulation Disorder, See [[Bleeding Disorder]] or [[Thrombophilia]]

Coccydynia, See [[Back Conditions]]

[[Coeliac Disease]]

[[Cold]]

Coldsore, See [[Herpes Simplex Virus]]

[[Colitis]]

Cone Biopsy, See [[Cervical Carcinoma In-Situ]]

[[Congenital Adrenal Hyperplasia]]

Congenital Dwarfism, See [[Achondroplasia]]

[[Congenital Naevus]]

[[Congo Fever]]

Conn Syndrome, See [[Hyperaldosteronism]]

[[Conversion Disorder]]

COPD, See [[Chronic Obstructive Pulmonary Disease]]

[[Corneal Transplant]]

Coronary Artery Disease, See [[Heart, Coronary Artery Disease]]

Coronary Thrombosis, See [[Heart, Coronary Artery Disease]]

[[Costochondritis]]

[[Cow Pox]]

Coxsackie Virus, See [[Infection, Acute]]

Creutzfeld-Jacob Disease, See [[Prion-Associated Disease]]

[[Crigler-Najjar Sydrome]]

Crimean Fever, See [[Brucellosis]]

Crimean-Congo Haemorrhagic Fever, See [[Congo Fever]]

Crohns Disease, See [[Inflammatory Bowel Disease]]

Crush Fracture (Spinal), See [[Back Conditions]]

[[Cushing Syndrome/Disease]]

Cutaneous Leishmaniasis, See [[Leishmaniasis]]

[[Cystic Fibrosis]]

[[Cystic Fibrosis Carrier]]

[[Cystinuria]]

[[Cysts]]

[[Cytomegalovirus]]

==D==

[[Darier Disease]]

Deep Vein Thrombosis, See [[Thrombosis]]

Dengue Fever, See [[Infection, Acute]]

[[Depression]]

[[Dermatitis]]

[[Dermatitis Herpetiformis]]

[[Dermatomyositis]]

[[Dextrocardia]]

[[Diabetes Insipidus]]

[[Diabetes Mellitus]]

Diamond-Blackfan Syndrome, see [[Inherited Disease]]

Diclofenac, See [[Non Steroidal Anti-Inflammatory Drug]]

[[Disabled Volunteer]]

Disc (Removal/Micro Discectomy), See [[Back Conditions]]

Disc Protrusion/Prolapse, See [[Back Conditions]]

Discoid Lupus, See [[Systemic Lupus Erythematosus]]

[[Diverticulitis]]

Double-Jointed, See [[Hypermobility Syndrome]]

[[Down Syndrome]]

Drug Abuse, See [[Addiction and Drug Abuse]]

Drug Treatment, See [[Medications]]

Drug Trial, See [[Clinical Trial]]

[[Duodenal Ulcer]]

[[Duplex Kidney]]

[[Dutasteride]]

Dwarfism, See [[Achondroplasia]]

Dysentery, See [[Infection, Acute]]

Dysfibrinogenaemia, See [[Bleeding Disorder]]

Dyspepsia, See [[Gastro-Oesophageal Reflux]]

[[Diastasis Symphysis Pubis]]

Dystonia, See [[Central Nervous System Disease]]

==E==

[[Ebola Fever]]

EBV, See [[Epstein-Barr Virus]]

Eclampsia, See [[Pre-Eclampsia]]

[[Eczema]]

[[Ehlers-Danlos Syndrome]]

[[Electrolysis]]

Elephantiasis, See [[Filariasis]]

Emphysema, See [[Chronic Obstructive Pulmonary Disease]]

[[Encephalitis]]

[[Endocarditis]]

[[Endometriosis]]

[[Epidermolysis Bullosa]]

[[Epilepsy]]

Episcleritis, See [[Eye Disease]]

[[Epistaxis]]

[[Epstein-Barr Virus]]

ERPC (Evacuation Of Retained Products Of Conception), See [[Surgery]]

[[Erysipelas]]

[[Erythema Multiforme]]

[[Erythema Nodosum]]

[[Erythromelalgia]]

Essential Thrombocythemia, See [[Myeloproliferative Neoplasm]]

[[Essential Tremor]]

[[Eye Disease]]

==F==

[[Factor 12 (XII) Deficiency]]

Factor 5 Leiden, See [[Thrombophilia]]

Factor 5 (V), 7 (VII), 8 (VIII), 9 (IX), 11 (XI) Deficiency, See [[Bleeding Disorder]]

Factor V Leiden, See [[Thrombophilia]]

Familial Hypercholesterolaemia, See [[Hyperlipidaemia]]

[[Familial Mediterranean Fever]]

[[Familial Polyposis]]

[[Fat Embolism]]

Felty Syndrome, See [[Rheumatoid Arthritis]]

Fertility Treatment, See [[Hormone Replacement Therapy]]

[[Fibroids]]

[[Fibromyalgia]]

Fibrosarcoma, See [[Malignancy]]

[[Fibrosing Alveolitis]]

[[Filariasis]]

[[Finasteride]]

Flu, See [[Influenza]]

[[Folate Deficiency]]

[[Fracture]]

[[Fragile X Syndrome]]

==G==

[[G6PD Deficiency]]

[[Galactosaemia]]

[[Gall-Bladder Disease]]

Gallstones, See [[Gall-Bladder Disease]]

Gammopathy, See [[Malignancy]]

[[Ganglion]]

[[Gastrectomy]]

[[Gastric Ulcer]]

[[Gastritis]]

[[Gastro-Oesophageal Reflux]]

[[Gaucher Disease]]

[[Gender Reassignment]]

Genetic Traits, See [[Inherited Disease]]

Genital Herpes, See [[Herpes Simplex Virus]]

[[Genital Warts]]

[[Giant Cell Tumour]]

[[Giardiasis]]

[[Gilbert Syndrome]]

[[Gilles De La Tourette Syndrome]]

Glandular Fever, See [[Epstein-Barr Virus]]

Glaucoma, See [[Eye Disease]]

[[Glomerulonephritis]]

Gluten Intolerance, See [[Coeliac Disease]]

Goitre (Enlarged Thyroid), See [[Thyroid Disease]]

[[Gonorrhoea]]

[[Gout]]

[[Granuloma Annulare]]

Graves Disease, See [[Thyroid Disease]]

Growth Hormone Therapy, See [[Hormone Replacement Therapy]]

[[Guillain-Barre Syndrome]]

Guttate Psoriasis, See [[Psoriasis]]

==H==

H. Pylori, See [[Helicobacter Pylori]]

[[Haemangioma]]

[[Haematemesis]]

[[Haematuria]]

[[Haemochromatosis]]

Haemoglobin C, See [[Haemoglobin Disorder]]

Haemoglobin Camden, See [[Haemoglobin Disorder]]

Haemoglobin D, See [[Haemoglobin Disorder]]

[[Haemoglobin Disorder]]

Haemoglobin E, See [[Haemoglobin Disorder]]

Haemoglobin Level, See [[Anaemia]]

Haemoglobin S, , See [[Haemoglobin Disorder]]

[[Haemolytic Anaemia]]

[[Haemolytic Uraemic Syndrome]]

Haemophilia, See [[Bleeding Disorder]]

Haemophilia Carrier, See [[Bleeding Disorder]]

[[Hand Foot And Mouth]]

Hashimotos Thyroiditis, See [[Thyroid Disease]]

Heart Attack, See [[Heart, Coronary Artery Disease]]

Heart Block, See [[Heart, Arrhythmia]]

Heart Murmur, See [[Heart, Valve Disease]]

[[Heart, Arrhythmia]]

[[Heart, Congenital Defect]]

[[Heart, Coronary Artery Disease]]

[[Heart, Muscle Disease]]

[[Heart, Valve Disease]]

Heavy Periods, See [[Menorrhagia]]

[[Helicobacter Pylori]]

[[HELLP Syndrome]]

Henoch-Schonlein Purpura, See [[Vasculitis]]

[[Hepatitis A]]

[[Hepatitis B]]

[[Hepatitis C]]

[[Hepatitis E]]

[[Hepatitis Of Unknown Origin]]

[[Hereditary Elliptocytosis]]

[[Hereditary Haemorrhagic Telangiectasia]]

[[Hereditary Motor Sensory Neuropathy]]

Hereditary Polyposis, See [[Familial Polyposis]]

Hereditary Spastic Paraplegia, See [[Central Nervous System Disease]]

[[Hereditary Spherocytosis]]

[[Hernia]]

[[Herpes Simplex Virus]]

Herpes Zoster Virus, See [[Chicken Pox]]

High Affinity Haemoglobin, See [[Haemoglobin Disorder]]

High Cholesterol, See [[Hyperlipidaemia]]

[[High Risk Sexual Behaviour]]

[[Hip Dislocation]]

[[Hirschsprung’s Disease]]

[[HIV]]

Hodgkin Lymphoma, See [[Malignancy]]

[[Hormone Replacement Therapy]]

HRT, See [[Hormone Replacement Therapy]]

[[HTLV Infection]]

Hughes Syndrome, See [[Anti-Phospholipid Syndrome]]

Human Bite, See [[Innoculation Injury]]

Human Growth Hormone], See [[Hormone Replacement Therapy]]

Human Immunodeficiency Virus, See [[HIV]]

[[Human Papilloma Virus]]

[[Huntington Disease]]

Hydatidiform Mole, See [[Pregnancy]]

[[Hydradentis Suppurativa]]

[[Hydrocephalus]]

[[Hydronephrosis]]

[[Hyperaldosteronism]]

Hypercholesterolaemia, See [[Hyperlipidaemia]]

[[Hyperlipidaemia]]

[[Hypermobility Syndrome]]

[[Hyperparathyroidism]]

Hyperprolactinaemia, See [[Pituitary Adenoma]]

[[Hypertension]]

Hyperthyroidism, See [[Thyroid Disease]]

[[Hypertrophic Obstructive Cardiomyopathy]]

Hypoadrenalism, See [[Addison Disease]]

Hypofibrinogenaemia, See [[Bleeding Disorder]]

[[Hypogonadism]]

[[Hypoparathyroidism]]

[[Hypopituiarism]]

[[Hypotension]]

Hypothyroidism, See [[Thyroid Disease]]

Hysterectomy, See [[Surgery]]

==I==

Ibuprofen, See [[Non Steroidal Anti-Inflammatory Drug]]

[[Idiopathic Hypersomnia]]

[[Idiopathic Intracranial Hypertension]]

[[IgA Deficiency]]

IgA Nephropathy, See [[Kidney Disease]]

[[Ileostomy]]

Immune Deficiency, See [[Immunosuppression]]

[[Immune Thrombocytopenia]]

[[Immunisation]]

Immunoglobulin Therapy, See [[Transfusion]]

[[Immunosuppression]]

[[Impetigo]]

In-vitro Fertilisation, Seee [[Hormone Replacement Therapy]]

[[Infection, Acute]]

Infectious Mononucleosis, See [[Epstein-Barr Virus]]

Infective Endocarditis, See [[Endocarditis]]

[[Infertility]]

[[Inflammatory Bowel Disease]]

[[Influenza]]

Influenza Vaccination, See [[Immunisation]]

[[Inherited Disease]]

[[Innoculation Injury]]

Intermittent Claudication, See [[Peripheral Vascular Disease]]

[[Iron Deficiency (Anaemia)]]

[[Irritable Bowel Disease]]

Ischaemic Heart Disease, See [[Heart, Coronary Artery Disease]]

IVF, See [[Hormone Replacement Therapy]]

==J==

[[Jaundice]]

Juvenile Chronic Arthritis, See [[Juvenile Idiopathic Arthritis]]

[[Juvenile Idiopathic Arthritis]]

Juvenile Rheumatoid Arthritis, See [[Juvenile Idiopathic Arthritis]]

==K==

Kala-Azar, See [[Leishmaniasis]]

[[Kallman Syndrome]]

[[Kawasaki Disease]]

Key-Hole Surgery, See [[Surgery]]

[[Kidney Disease]]

Kidney Transplant, See [[Tissue Or Organ Transplant]]

[[Kidney, Single]]

Kienbock Disease, See [[Avascular Necrosis]]

[[Klinefelter Syndrome]]

Kyphosis, See [[Back Conditions]]

==L==

[[Labyrinthitis]]

Laminectomy, See [[Back Conditions]]

Laparoscopy, See [[Surgery]]

[[Laser Treatment]]

[[Lassa Fever]]

Latex Allergy, See [[Allergy]]

Left Branch Bundle Block, See [[Heart, Arrhythmia]]

[[Legionnaire's Disease]]

[[Leishmaniasis]]

[[Leptospirosis]]

Leukaemia, See [[Malignancy]]

[[Lichen Planus]]

[[Lichen Sclerosus]]

[[Lipoma]]

[[Liver Function, Abnormal]]

Low Blood Pressure, See [[Hypotension]]

Low Haemoglobin, See [[Anaemia]]

Low Platelets, See [[Thrombocytopenia]]

Lumbar Spine Abnormality, See [[Back Conditions]]

Lupus, See [[Systemic Lupus Erythematosus]]

[[Lupus Anticoagulant]]

[[Lyme Disease]]

[[Lymphadenopathy]]

[[Lymphoedema]]

[[Lymphogranuloma Venereum]]

==M==

[[Macrocytosis]]

[[Malaria]]

[[Malignancy]]

[[Malignant Hyperpyrexia]]

Malignant Melanoma, See [[Malignancy]]

Manic Depression, See [[Bipolar Affective Disorder]]

[[Marburg Fever]]

[[Marfan Syndrome]]

Mastectomy, See [[Surgery]]

[[Mastitis]]

Mastoid Operation, See [[Surgery]]

ME, See [[Myalgic Encephalomyelitis]]

Medical Trial, See [[Clinical Trial]]

[[Medications]]

[[Megaloblastic Anaemia]]

Membranous Glomerulonephritis, See [[Kidney Disease]]

[[Meniere Disease]]

Meningioma, See [[Brain Tumour]]

[[Meningitis]]

Meningoencephalitis, See [[Meningitis]]

[[Menopause]]

[[Menorrhagia]]

Metabolic Disease, Seee [[Inherited Disease]]

MGUS, See [[Monoclonal Gammopathy]]

Micropituitary Adenoma, See [[Pituitary Adenoma]]

[[Migraine]]

[[Miscarriage]]

Mitral Regurgitation, See [[Heart, Valve Disease]]

Mitral Stenosis, See [[Heart, Valve Disease]]

Mitral Valve Disease, See [[Heart, Valve Disease]]

[[Monoclonal Gammopathy]]

[[Mononeuritis]]

Mononucleosis, See [[Epstein-Barr Virus]]

[[Morphoea]]

Motor Neurone Disease, See [[Central Nervous System Disease]]

Motor Sensory Neuropathy, See [[Hereditary Motor Sensory Neuropathy]]

[[MRSA]]

MS, See [[Multiple Sclerosis]]

[[Multiple Sclerosis]]

[[Muscular Dystrophy]]

[[Muscular Dystrophy Carrier]]

[[Myalgic Encephalomyelitis]]

[[Myasthenia Gravis]]

[[Myelodysplasia]]

Myelofibrosis, See [[Myeloproliferative Neoplasm]]

[[Myeloproliferative Neoplasm]]

[[Myocarditis]]

Myoclonus, See [[Central Nervous System Disease]]

[[Myositis]]

Myotonia Congenita, See [[Muscular Dystrophy]]

Myotonic Dystrophy, See [[Muscular Dystrophy]]

Myxoedema, See [[Thyroid Disease]]

[[Myxoma]]

==N==

[[Narcolepsy]]

[[Needle Phobia]]

Needlestick Injury, See [[Innoculation Injury]]

Neotigason, See [[Acne]]

Nephrectomy (Kidney Removal), See [[Kidney, Single]]

Nephritis, See [[Kidney Disease]]

Nephropathy, See [[Kidney Disease]]

Nephrotic Syndrome, See [[Kidney Disease]]

[[Neurofibromatosis]]

Neuroma, See [[Brain Tumour]]

[[Neurosurgery]]

[[Neutropenia]]

[[Non Steroidal Anti-Inflammatory Drug]]

Non-Hodgkin Lymphoma, See [[Malignancy]]

Nose Bleed, See [[Epistaxis]]

NSAID, See [[Non Steroidal Anti-Inflammatory Drug]]

==O==

Obesity, See [[Weight]]

[[Obsessive Compulsive Disorder]]

[[Obstetric Cholestasis]]

[[Obstructive Sleep Apnoea]]

[[Ocular Surgery]]

[[Ocular Tissue Recipient]]

Oesophagitis, See [[Gastro-Oesophageal Reflux]]

[[Onchocerciasis]]

Operation, See [[Surgery]]

[[Optic Neuritis]]

[[Osgood Schlatter Disease]]

Osler-Weber-Rendu Disease, See [[Hereditary Haemorrhagic Telangiectasia]]

[[Osteoarthritis]]

[[Osteochondroma]]

Osteodystrophia Deformans, See [[Paget Disease]]

[[Osteogenesis Imperfecta]]

Osteoma, See [[Osteochondroma]]

[[Osteomalacia]]

[[Osteomyelitis]]

[[Osteopenia]]

[[Osteoporosis]]

[[Otosclerosis]]

[[Ovarian Cyst]]

==P==

Pacemaker, See [[Heart, Arrhythmia]]

[[Paget Disease]]

Paget Disease Of The Nipple, See [[Malignancy]]

[[Palindromic Rheumatism]]

[[Pancreatitis]]

Panic Attacks, See Anxiety Disorder

Paraplegia, See [[Disabled Volunteer]]

Paraprotein, See [[Monoclonal Gammopathy]]

[[Paratyphoid Fever]]

Parkinson Disease, See [[Central Nervous System Disease]]

[[Parvovirus]]

Patent Ductus Arteriosus, See [[Heart, Congenital Defect]]

Patent Foramen Ovale, See [[Heart, Congenital Defect]]

[[Pelvic Inflammatory Disease]]

[[Pemphigoid]]

[[Pemphigus]]

[[Peptic Ulcer]]

[[Pericarditis]]

[[Peripheral Neuropathy]]

[[Peripheral Vascular Disease]]

[[Peritonitis]]

[[Pernicious Anaemia]]

Peroneal Muscular Atrophy, See [[Hereditary Motor Sensory Neuropathy]]

[[Perthes Disease]]

[[Peyronie Disease]]

Phaeochromocytoma, See [[Malignancy]]

[[Phenylketonuria]]

[[Phlebitis]]

[[Pilonidal Sinus]]

[[Pituitary Adenoma]]

[[Pityriasis]]

[[Pleural Effusion]]

[[Pleurisy]]

[[Pneumonia]]

[[Pneumothorax]]

Polio, See [[Disabled Volunteer]]

Polyarteritis Nodosa, See [[Vasculitis]]

[[Polycystic Kidney Disease]]

[[Polycystic Ovarian Syndrome]]

[[Polycythaemia]]

Polycythemia Rubra Vera, See [[Myeloproliferative Neoplasm]]

[[Polymyalgia]]

[[Porphyria (All Types)]]

Positive Cervical Smear, See [[Cervical Carcinoma In-Situ]]

Post-Viral Fatigue Syndrome, See [[Myalgic Encephalomyelitis]]

[[POTS (Postural Orthostatic Tachycardia Syndrome)]]

[[Pre-Cancerous Cells]]

[[Pre-Eclampsia]]

[[Pregnancy]]

[[Prion-Associated Disease]]

[[Proctitis]]

[[Prolactinoma]]

Prolapsed Disc, See [[Back Conditions]]

[[Prostate, Enlarged]]

Prostatism, See [[Benign Prostatic Hyperplasia]]

Protein C Deficiency, See [[Thrombophilia]]

Protein S Deficiency, See [[Thrombophilia]]

Prothrombin Gene Mutation, See [[Thrombophilia]]

[[Psoriasis]]

Psoriatic Arthritis, See [[Psoriasis]]

Pulmonary Embolus, See [[Thrombosis]]

Pulmonary Stenosis / Regurgitation, See [[Heart, Congenital Defect]]

Pulmonary Valvotomy, See [[Heart, Valve Disease]]

[[Purpura]]

Pyelonephritis, See [[Kidney Disease]]

[[Pyloric Stenosis]]

[[Pyruvate Kinase Deficiency]]

==Q==

[[Q Fever]]

==R==

[[Rabies]]

[[Radionuclide Therapy]]

[[Radiotherapy]]

[[Raynaud Disease]]

[[Reactive Arthritis]]

[[Reflex Sympathetic Dystrophy]]

Reflux, See [[Gastro-Oesophageal Reflux]]

Reiter Syndrome, See [[Reactive Arthritis]]

Renal Colic, See [[Kidney Disease]]

Renal Disease, See [[Kidney Disease]]

[[Restless Legs Syndrome]]

[[Retinitis Pigmentosa]]

[[Retinoic Acid Derivatives]]

[[Reye Syndrome]]

[[Rheumatic Fever]]

[[Rheumatoid Arthritis]]

[[Rhinitis]]

Ricketts, See [[Disabled Volunteer]]

[[Rickettsial Infection]]

Right Bundle Branch Block, See [[Heart, Arrhythmia]]

[[Ringworm]]

River Blindness, See [[Onchocerciasis]]

Roaccutane, See [[Acne]]

Rocky Mountain Spotted Fever, See [[Rickettsial Infection]]

Rodent Ulcer, See [[Basal Cell Carcinoma]]

[[Rosacea]]

==S==

Sacroiliac Joint Problems, See [[Back Conditions]]

Sandhoff Disease, See [[Inherited Disease]]

[[Sarcoidosis]]

[[Scarlet Fever]]

Scheuermann Disease, See [[Back Conditions]]

[[Schistosomiasis]]

[[Schizophrenia]]

Schwannoma, See [[Acoustic Neuroma]]

Sciatica, See [[Back Conditions]]

[[Scleroderma]]

Scoliosis, See [[Back Conditions]]

[[Sebaceous Cyst]]

[[Seborrhoeic Dermatitis]]

Seizures, See [[Epilepsy]]

[[Septicaemia]]

Sex Change, See [[Gender Reassignment]]

[[Sexual Orientation]]

[[Sexually Transmitted Diseases]]

Shingles, See [[Chicken Pox]]

Shwachman-Diamond Syndrome, See [[Inherited Disease]]

[[Sickle Cell Disease]]

[[Sickle Cell Trait]]

[[Simple Cyst]]

[[Situs Inversus]]

[[Sjogren’s Syndrome]]

Sleeping Sickness, See [[African Trypanosomiasis]]

Smear - Abnormal Cervical, See [[Cervical Carcinoma In-Situ]]

[[South American Trypanosomiasis]]

Spasmodic Torticollis, See [[Back Conditions]]

Spherocytosis, See [[Hereditary Spherocytosis]]

[[Spina Bifida]]

Spinal Fusion, See [[Back Conditions]]

Spinal Muscular Atrophy, See [[Inherited Disease]]

Spinal Stenosis, See [[Back Conditions]]

[[Spitz Naevus]]

[[Splenectomy]]

Spondylolisthesis, See [[Back Conditions]]

Spondylosis, See [[Back Conditions]]

Spot Baldness, See [[Alopecia Areata]]

Spots, See [[Acne]]

[[Steroid Treatment]]

[[Stevens-Johnson Syndrome]]

Stickler Syndrome, See [[Inherited Disease]]

[[Still Disease]]

[[Stroke]]

[[Subarachnoid Haemorrhage]]

[[Subdural Haematoma]]

[[Subglottic Stenosis]]

Superficial Thrombophlebitis, See [[Thrombosis]]

Supraventricular Tachycardia, See [[Heart, Arrhythmia]]

[[Surgery]]

[[Suxamethonium Allergy]]

Sydenham Chorea, See [[Rheumatic Fever]]

[[Syphilis]]

[[Syringomyelia]]

[[Systemic Lupus Erythematosus]]

==T==

Tachycardia, See [[Heart, Arrhythmia]]

Takayasu Arteritis, See [[Vasculitis]]

Tattoo, See [[Body Piercing]]

Tay Sachs Disease, See [[Inherited Disease]]

Temporal Arteritis, See [[Vasculitis]]

Temporal Lobectomy, See [[Neurosurgery]] and [[Epilepsy]]

Termination Of Pregnancy, See [[Pregnancy]] and [[Surgery]]

Testosterone Injections, See [[Hormone Replacement Therapy]] and [[Addiction and Drug Abuse]]

Tetralogy Of Fallot, See [[Heart, Congenital Defect]]

Tetraplegia, See [[Disabled Volunteer]]

Thalassaemia Major, See [[Haemoglobin Disorder]]

Thalassaemia Trait (Minor), See [[Haemoglobin Disorder]]

[[Thoracic Outlet Syndrome]]

Thrombocythemia, See [[Thrombocytosis]]

[[Thrombocytopenia]]

[[Thrombocytosis]]

[[Thrombophilia]]

Thrombophlebitis, See [[Thrombosis]]

[[Thrombosis]]

Thrush, See [[Candida Infection]]

[[Thyroid Disease]]

Thyrotoxicosis, See [[Thyroid Disease]]

Tick Typhus, See [[Rickettsial Infection]]

[[Tissue Or Organ Transplant]]

[[Toxoplasmosis]]

[[Transfusion]]

Transient Ischaemic Attack (TIA), See [[Stroke]]

[[Transsexual]]

Treacher-Collins Syndrome, See [[Inherited Disease]]

Trial, See [[Clinical Trial]]

Tricuspid Regurgitation, See [[Heart, Valve Disease]]

Tricuspid Stenosis, See [[Heart, Valve Disease]]

[[Trigeminal Neuralgia]]

Trypanosoma Cruzi Infection, See [[South American Trypanosomiasis]]

[[Tuberculosis]]

[[Turner Syndrome]]

[[Typhoid]]

==U==

Ulcerative Colitis, See [[Inflammatory Bowel Disease]]

[[Urticaria]]

Uterine Fibroid, See [[Fibroids]]

Uveitis, See [[Eye Disease]]

==V==

Vaccine, See [[Immunisation]]

Vaccination, See [[Immunisation]]

Varicella Zoster, See [[Chicken Pox]]

[[Varicose Veins]]

[[Vasculitis]]

[[Vasovagal Attack]]

[[Venesection]]

Ventricular Septal Defect, See [[Heart, Congenital Defect]]

Vestibular Schwannoma, See [[Acoustic Neuroma]]

Visceral Leishmaniasis, See [[Leishmaniasis]]

[[Vitiligo]]

Von Recklinghausen Disease, See [[Neurofibromatosis]]

Von Willebrand Disease, See [[Bleeding Disorder]]

==W==

Warts, See [[Human Papilloma Virus]]

Wegener Granulomatosis, See [[Vasculitis]]

[[Weight]]

Weil Disease, See [[Leptospirosis]]

Werdnig-Hoffmann Disease, See [[Inherited Disease]]

[[West Nile Virus]]

[[Wilson Disease]]

Wolff-Parkinson-White Syndrome, See [[Heart, Arrhythmia]]

==X==

==Y==

[[Yaws]]

Yellow Fever, See [[Infection, Acute]]

Yellow Fever Vaccine, See [[Immunisation]]

==Z==

=Appendix 1 - Haematologic and biochemical testing at donor medical=

'''The following haematological and biochemical tests are performed at the donor medical:'''

Full blood count

Urea and Electrolytes

Liver function tests

Bone function tests

Cholesterol

Random glucose

Coagulation screen (PT, APTT and fibrinogen)

ABO and Rh blood grouping

Pregnancy test (B-HCG), if relevant

=Appendix 2 - Infectious disease marker testing at ET/CT and donor medical=

'''The following infectious disease markers are tested for all donors at the donor medical:'''

HIV (P24 antigen and antibody)

Hepatitis B (surface antigen and core antibody)

Hepatitis C (antibody and RNA)

HTLV I+II (antibody)

Syphilis (antibody)

Toxoplama (antibody)

EBV (VCA/NA IgG)

CMV (IgG)

Varicella (IgG)

'''The following infectious disease markers may be tested if a relevant travel history is given by the donor, at the discretion of the harvest physician or Anthony Nolan medical officer:'''

Malarial antigen/antibodies

T.cruzi (Chagas disease) antibodies

West nile virus NAT

=Appendix 3 - Other investigations at donor medical=

Electrocardiogram (ECG)

Chest X-ray

=Appendix 4 - Special consideration for donors in the Armed Forces=

'''Guidance for Armed Forces donors'''

It is recognised that members of the Armed Forces will need to get permission from the Commanding Officer prior to donation. Certain occupations within the MOD, such as aircrew within the RAF, will not allow donation by bone marrow harvest unless it is to a family member, although peripheral blood stem cell donation is permitted.

As a consequence, members of the Armed Forces are permitted to join the register as ‘PBSC only’ if there are concerns about the impact of bone marrow harvest on their ability to fulfil their role, or concerns about possible impact on their career.

Main Page

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=About the Anthony Nolan Medical and Lifestyle Guidelines=

For potential and current donors, please note that these guidelines are primarily intended for use by Anthony Nolan staff.

The Anthony Nolan Medical and Lifestyle Guidelines are put in place to ensure the safety of both our stem cell donors and the recipients of their donations.

Because of the volunteer nature of stem cell donation, we have a responsibility to ensure that our donors are able to donate safely, with minimal risk to their own health. For this reason, our medical criteria are strict, and considerably more strict than medical criteria for having a procedure, such as an operation, for the benefit of your own health.

Some donor medical conditions present a risk to the '''recipient''' of the donation. In these cases, we may allow a donor to donate because the benefit for the patient of receiving the transplant outweighs the risk.

=Guidance for Recruiters=

The list is not exhaustive; therefore, particular cases may require further clarification by our Medical Officer.

IN SUCH CASES PLEASE NOTE THE FOLLOWING:
The volunteer should be asked to complete an application form giving full details of their
medical status ensuring that the following information is given:

*Name of medical condition.
*Date of diagnosis.
*Name of medication(s) taken.
*Length of time medication has been taken.
*Is the medication seen as a short course or long-term prescription?
*Does the volunteer have any limitations to life-style?
*Is the volunteer’s condition regularly assessed by GP/Consultant?

Once the application has been reviewed the donor will be contacted and informed
of the decision.

This list is in place to help us recruit medically eligible volunteer blood stem cell donors.
We have a duty to ensure that volunteer donors are put at minimal risk whilst also considering the safety and outcome for transplant recipients.

The criteria, which we use to assess the suitability of a volunteer to donate, are considerably
more stringent than those taken into consideration for volunteers undergoing a procedure for
their own medical health status.

If you have any queries please contact The Anthony Nolan Donor Support Team
as follows:

Telephone 0303 303 0303 (9am – 5pm) and ask for The Donor Support Team or
E-mail: info@anthonynolan.org

=Recently Updated Guidance=

'''24/10/12. Guidance Added:''' [[Breast Feeding]]

'''04/01/13. Guidance updated:''' [[Weight]]

'''02/05/14. Guidance updated:''' [[Retinoic Acid Derivatives]]

=Multiple Medical Conditions=

Some donors will have more than one medical problem, and the potential combinations are too numerous to list in this guidance. Some combinations of conditions will increase the risk of donor harm, despite being acceptable in isolation.

For example, hypertension, smoking, high cholesterol and diet-controlled diabetes may all be acceptable, but this combination in an older donor would considerably increase their risk of a heart attack or stroke.

If in doubt, please discuss these donors with the medical officer.

=Index of Conditions=

==A==

Accident, See [[Fracture]] and/or [[Surgery]]

[[Acetylcholinesterase Deficiency]]

[[Achondroplasia]]

Acitretin, See [[Acne]]

[[Acne]]

[[Acoustic Neuroma]]

Acoustic Schwannoma, See [[Acoustic Neuroma]]

[[Acromegaly]]

[[Actinic Prurigo]]

[[Acupuncture]]

ADD, See [[Attention Deficit Hyperactivity Disorder]]

[[Addiction and Drug Abuse]]

[[Addison Disease]]

Adenocarcinoma, See [[Malignancy]]

[[Adenoma]]

ADHD, See [[Attention Deficit Hyperactivity Disorder]]

Adrenal Hyperplasia, See [[Congenital Adrenal Hyperplasia]]

[[African Trypanosomiasis]]

AIDS, See [[HIV]]

[[Albino]]

[[Alcohol Intake]]

[[Allergy]]

[[Alopecia]]

[[Alpha 1 Antitrypsin Deficiency]]

[[Alpha Mannosidosis]]

[[Alports Syndrome]]

Anabolic Steroids, See [[Addiction and Drug Abuse]]

[[Anaemia]]

[[Anaesthetic Complications]]

Angina, See [[Heart, Coronary Artery Disease]]

[[Animal Bite]]

[[Ankylosing Spondylitis]]

Anthrax Vaccine, See [[Immunisation]]

Anti-Inflammatory Drug, See [[Non Steroidal Anti-Inflammatory Drug]]

[[Anti-Phospholipid Syndrome]]

[[Antibiotic Treatment]]

[[Antibodies]]

[[Anticoagulants]]

Anticonvulsants, See [[Epilepsy]]

Antithrombin Deficiency, See [[Thrombophilia]]

[[Anxiety Disorder]]

Aortic Regurgitation, See [[Heart, Valve Disease]]

Aortic Stenosis, See [[Heart, Valve Disease]]

Aortic Valve Disease, See [[Heart, Valve Disease]]

[[Arachnoid Cyst]]

[[Arnold-Chiari Syndrome]]

Arrhythmia, See [[Heart, Arrhythmia]]

[[Arthrogryposis]]

Arthroscopy, See [[Surgery]]

[[Asperger Syndrome]]

Aspirin, See [[Non Steroidal Anti-Inflammatory Drug]]

[[Asthma]]

Atherosclerosis, See [[Heart, Coronary Artery Disease]]

Atrial Fibrillation, See [[Heart, Arrhythmia]]

Atrial Myxoma, See [[Myxoma]]

Atrial Septal Defect (ASD), See [[Heart, Congenital Defect]]

[[Attention Deficit Hyperactivity Disorder]]

[[Avascular Necrosis]]

Avodart, See [[Dutasteride]]

Avulsion Fracture (Other Than Spinal), See [[Fracture]]

Avulsion Fracture (Spinal), See [[Back Conditions]]

==B==

[[B12 Deficiency]]

[[Babesiosis]]

[[Back Conditions]]

[[Balanitis Xerotica Obliterans (BXO)]]

[[Basal Cell Carcinoma]]

BCG Vaccination, See [[Immunisation]]

[[Bells Palsy]]

Benign Essential Tremor, See [[Essential Tremor]]

Benign Ethnic Neutropenia, See [[Neutropenia]]

Benign Intracranial Hypertension, See [[Idiopathic Intracranial Hypertension]]

[[Benign Positional Vertigo]]

[[Benign Prostatic Hyperplasia]]

Berger Disease, See [[Kidney Disease]]

Beta Blockers, See [[Medications]]

Beta Thalassemia, See [[Haemoglobin Disorder]]

Bilateral Scleritis, See [[Eye Disease]]

Bilharzia, See [[Schistosomiasis]]

[[Bipolar Affective Disorder]]

Bisexual, See [[Sexual Orientation]]

[[Bleeding Disorder]]

Blocked Artery (Heart), See [[Heart, Coronary Artery Disease]]

Blood Clot, See [[Thrombosis]]

Blood Pressure, See [[Hypertension]]

Blood Transfusion, See [[Transfusion]]

[[Body Piercing]]

Bone Density (Abnormal), See [[Osteoporosis]]

Bone Graft, See [[Surgery]] and/or [[Back Conditions]]

Borreliosis, See [[Lyme Disease]]

Bowens Disease, See [[Malignancy]]

BPH, See [[Benign Prostatic Hyperplasia]]

Brain Surgery, See [[Neurosurgery]]

[[Brain Tumour]]

[[Breast Augmentation (Implants)]]

[[Breast Feeding]]

[[Bronchiectasis]]

Bronchitis, See [[Infection, Acute]]

Brown-Sequard Syndrome, See [[Central Nervous System Disease]]

[[Brucellosis]]

[[Bursitis]]

==C==

[[C1 Esterase Inhibitor Deficiency]]

Cancer, See [[Malignancy]]

[[Candida Infection]]

Candidiasis, See [[Candida Infection]]

Carcinoid Syndrome, See [[Malignancy]]

Cardiac Failure, See [[Heart, Muscle Disease]]

Cardiac Syndrome X, See [[Heart, Coronary Artery Disease]]

Cardiomegaly, See [[Heart, Muscle Disease]]

Cardiomyopathy, See [[Heart, Muscle Disease]]

[[Carpal Tunnel Syndrome]]

Cat-Scratch Fever, See [[Infection, Acute]]

[[Causalgia]]

Cellulitis, See [[Infection, Acute]]

[[Central Nervous System Disease]]

Cerebral Malaria, See [[Malaria]]

[[Cerebral Palsy]]

[[Cerebroretinal Angiomatosis]]

Cerebrovascular Accident, See [[Stroke]]

[[Cervical Carcinoma In-Situ]]

Cervical Smear, See [[Cervical Carcinoma In-Situ]]

Cervical Spondylosis, See [[Back Conditions]]

Chagas Disease, See [[South American Trypanosomiasis]]

Charcot Marie Tooth Syndrome, See [[Hereditary Motor Sensory Neuropathy]]

[[Chicken Pox]]

Chlamydia, See [[Infection, Acute]]

Cholecystectomy, See [[Surgery]]

Cholecystitis, See [[Gall-Bladder Disease]]

[[Chondromalacia Patellae]]

Christmas Disease, See [[Bleeding Disorder]]

Chronic Fatigue Syndrome, See [[Myalgic Encephalomyelitis]]

[[Chronic Obstructive Pulmonary Disease]]

[[Cirrhosis]]

CJD, See [[Prion-Associated Disease]]

Clap, See [[Gonorrhoea]]

[[Clinical Trial]]

[[Cluster Headache]]

Coagulation Disorder, See [[Bleeding Disorder]] or [[Thrombophilia]]

Coccydynia, See [[Back Conditions]]

[[Coeliac Disease]]

[[Cold]]

Coldsore, See [[Herpes Simplex Virus]]

[[Colitis]]

Cone Biopsy, See [[Cervical Carcinoma In-Situ]]

[[Congenital Adrenal Hyperplasia]]

Congenital Dwarfism, See [[Achondroplasia]]

[[Congenital Naevus]]

[[Congo Fever]]

Conn Syndrome, See [[Hyperaldosteronism]]

[[Conversion Disorder]]

COPD, See [[Chronic Obstructive Pulmonary Disease]]

[[Corneal Transplant]]

Coronary Artery Disease, See [[Heart, Coronary Artery Disease]]

Coronary Thrombosis, See [[Heart, Coronary Artery Disease]]

[[Costochondritis]]

[[Cow Pox]]

Coxsackie Virus, See [[Infection, Acute]]

Creutzfeld-Jacob Disease, See [[Prion-Associated Disease]]

[[Crigler-Najjar Sydrome]]

Crimean Fever, See [[Brucellosis]]

Crimean-Congo Haemorrhagic Fever, See [[Congo Fever]]

Crohns Disease, See [[Inflammatory Bowel Disease]]

Crush Fracture (Spinal), See [[Back Conditions]]

[[Cushing Syndrome/Disease]]

Cutaneous Leishmaniasis, See [[Leishmaniasis]]

[[Cystic Fibrosis]]

[[Cystic Fibrosis Carrier]]

[[Cystinuria]]

[[Cysts]]

[[Cytomegalovirus]]

==D==

[[Darier Disease]]

Deep Vein Thrombosis, See [[Thrombosis]]

Dengue Fever, See [[Infection, Acute]]

[[Depression]]

[[Dermatitis]]

[[Dermatitis Herpetiformis]]

[[Dermatomyositis]]

[[Dextrocardia]]

[[Diabetes Insipidus]]

[[Diabetes Mellitus]]

[[Diamond-Blackfan Syndrome]]

Diclofenac, See [[Non Steroidal Anti-Inflammatory Drug]]

[[Disabled Volunteer]]

Disc (Removal/Micro Discectomy), See [[Back Conditions]]

Disc Protrusion/Prolapse, See [[Back Conditions]]

Discoid Lupus, See [[Systemic Lupus Erythematosus]]

[[Diverticulitis]]

Double-Jointed, See [[Hypermobility Syndrome]]

[[Down Syndrome]]

Drug Abuse, See [[Addiction and Drug Abuse]]

Drug Treatment, See [[Medications]]

Drug Trial, See [[Clinical Trial]]

[[Duodenal Ulcer]]

[[Duplex Kidney]]

[[Dutasteride]]

Dwarfism, See [[Achondroplasia]]

Dysentery, See [[Infection, Acute]]

Dysfibrinogenaemia, See [[Bleeding Disorder]]

Dyspepsia, See [[Gastro-Oesophageal Reflux]]

[[Diastasis Symphysis Pubis]]

Dystonia, See [[Central Nervous System Disease]]

==E==

[[Ebola Fever]]

EBV, See [[Epstein-Barr Virus]]

Eclampsia, See [[Pre-Eclampsia]]

[[Eczema]]

[[Ehlers-Danlos Syndrome]]

[[Electrolysis]]

Elephantiasis, See [[Filariasis]]

Emphysema, See [[Chronic Obstructive Pulmonary Disease]]

[[Encephalitis]]

[[Endocarditis]]

[[Endometriosis]]

[[Epidermolysis Bullosa]]

[[Epilepsy]]

Episcleritis, See [[Eye Disease]]

[[Epistaxis]]

[[Epstein-Barr Virus]]

ERPC (Evacuation Of Retained Products Of Conception), See [[Surgery]]

[[Erysipelas]]

[[Erythema Multiforme]]

[[Erythema Nodosum]]

[[Erythromelalgia]]

Essential Thrombocythemia, See [[Myeloproliferative Neoplasm]]

[[Essential Tremor]]

[[Eye Disease]]

==F==

[[Factor 12 (XII) Deficiency]]

Factor 5 Leiden, See [[Thrombophilia]]

Factor 5 (V), 7 (VII), 8 (VIII), 9 (IX), 11 (XI) Deficiency, See [[Bleeding Disorder]]

Factor V Leiden, See [[Thrombophilia]]

Familial Hypercholesterolaemia, See [[Hyperlipidaemia]]

[[Familial Mediterranean Fever]]

[[Familial Polyposis]]

[[Fat Embolism]]

Felty Syndrome, See [[Rheumatoid Arthritis]]

Fertility Treatment, See [[Hormone Replacement Therapy]]

[[Fibroids]]

[[Fibromyalgia]]

Fibrosarcoma, See [[Malignancy]]

[[Fibrosing Alveolitis]]

[[Filariasis]]

[[Finasteride]]

Flu, See [[Influenza]]

[[Folate Deficiency]]

[[Fracture]]

[[Fragile X Syndrome]]

==G==

[[G6PD Deficiency]]

[[Galactosaemia]]

[[Gall-Bladder Disease]]

Gallstones, See [[Gall-Bladder Disease]]

Gammopathy, See [[Malignancy]]

[[Ganglion]]

[[Gastrectomy]]

[[Gastric Ulcer]]

[[Gastritis]]

[[Gastro-Oesophageal Reflux]]

[[Gaucher Disease]]

[[Gender Reassignment]]

Genetic Traits, See [[Inherited Disease]]

Genital Herpes, See [[Herpes Simplex Virus]]

[[Genital Warts]]

[[Giant Cell Tumour]]

[[Giardiasis]]

[[Gilbert Syndrome]]

[[Gilles De La Tourette Syndrome]]

Glandular Fever, See [[Epstein-Barr Virus]]

Glaucoma, See [[Eye Disease]]

[[Glomerulonephritis]]

Gluten Intolerance, See [[Coeliac Disease]]

Goitre (Enlarged Thyroid), See [[Thyroid Disease]]

[[Gonorrhoea]]

[[Gout]]

[[Granuloma Annulare]]

Graves Disease, See [[Thyroid Disease]]

Growth Hormone Therapy, See [[Hormone Replacement Therapy]]

[[Guillain-Barre Syndrome]]

Guttate Psoriasis, See [[Psoriasis]]

==H==

H. Pylori, See [[Helicobacter Pylori]]

[[Haemangioma]]

[[Haematemesis]]

[[Haematuria]]

[[Haemochromatosis]]

Haemoglobin C, See [[Haemoglobin Disorder]]

Haemoglobin Camden, See [[Haemoglobin Disorder]]

Haemoglobin D, See [[Haemoglobin Disorder]]

[[Haemoglobin Disorder]]

Haemoglobin E, See [[Haemoglobin Disorder]]

Haemoglobin Level, See [[Anaemia]]

Haemoglobin S, , See [[Haemoglobin Disorder]]

[[Haemolytic Anaemia]]

[[Haemolytic Uraemic Syndrome]]

Haemophilia, See [[Bleeding Disorder]]

Haemophilia Carrier, See [[Bleeding Disorder]]

[[Hand Foot And Mouth]]

Hashimotos Thyroiditis, See [[Thyroid Disease]]

Heart Attack, See [[Heart, Coronary Artery Disease]]

Heart Block, See [[Heart, Arrhythmia]]

Heart Murmur, See [[Heart, Valve Disease]]

[[Heart, Arrhythmia]]

[[Heart, Congenital Defect]]

[[Heart, Coronary Artery Disease]]

[[Heart, Muscle Disease]]

[[Heart, Valve Disease]]

Heavy Periods, See [[Menorrhagia]]

[[Helicobacter Pylori]]

[[HELLP Syndrome]]

Henoch-Schonlein Purpura, See [[Vasculitis]]

[[Hepatitis A]]

[[Hepatitis B]]

[[Hepatitis C]]

[[Hepatitis E]]

[[Hepatitis Of Unknown Origin]]

[[Hereditary Elliptocytosis]]

[[Hereditary Haemorrhagic Telangiectasia]]

[[Hereditary Motor Sensory Neuropathy]]

Hereditary Polyposis, See [[Familial Polyposis]]

Hereditary Spastic Paraplegia, See [[Central Nervous System Disease]]

[[Hereditary Spherocytosis]]

[[Hernia]]

[[Herpes Simplex Virus]]

Herpes Zoster Virus, See [[Chicken Pox]]

High Affinity Haemoglobin, See [[Haemoglobin Disorder]]

High Cholesterol, See [[Hyperlipidaemia]]

[[High Risk Sexual Behaviour]]

[[Hip Dislocation]]

[[Hirschsprung’s Disease]]

[[HIV]]

Hodgkin Lymphoma, See [[Malignancy]]

[[Hormone Replacement Therapy]]

HRT, See [[Hormone Replacement Therapy]]

[[HTLV Infection]]

Hughes Syndrome, See [[Anti-Phospholipid Syndrome]]

Human Bite, See [[Innoculation Injury]]

Human Growth Hormone], See [[Hormone Replacement Therapy]]

Human Immunodeficiency Virus, See [[HIV]]

[[Human Papilloma Virus]]

[[Huntington Disease]]

Hydatidiform Mole, See [[Pregnancy]]

[[Hydradentis Suppurativa]]

[[Hydrocephalus]]

[[Hydronephrosis]]

[[Hyperaldosteronism]]

Hypercholesterolaemia, See [[Hyperlipidaemia]]

[[Hyperlipidaemia]]

[[Hypermobility Syndrome]]

[[Hyperparathyroidism]]

Hyperprolactinaemia, See [[Pituitary Adenoma]]

[[Hypertension]]

Hyperthyroidism, See [[Thyroid Disease]]

[[Hypertrophic Obstructive Cardiomyopathy]]

Hypoadrenalism, See [[Addison Disease]]

Hypofibrinogenaemia, See [[Bleeding Disorder]]

[[Hypogonadism]]

[[Hypoparathyroidism]]

[[Hypopituiarism]]

[[Hypotension]]

Hypothyroidism, See [[Thyroid Disease]]

Hysterectomy, See [[Surgery]]

==I==

Ibuprofen, See [[Non Steroidal Anti-Inflammatory Drug]]

[[Idiopathic Hypersomnia]]

[[Idiopathic Intracranial Hypertension]]

[[IgA Deficiency]]

IgA Nephropathy, See [[Kidney Disease]]

[[Ileostomy]]

Immune Deficiency, See [[Immunosuppression]]

[[Immune Thrombocytopenia]]

[[Immunisation]]

Immunoglobulin Therapy, See [[Transfusion]]

[[Immunosuppression]]

[[Impetigo]]

In-vitro Fertilisation, Seee [[Hormone Replacement Therapy]]

[[Infection, Acute]]

Infectious Mononucleosis, See [[Epstein-Barr Virus]]

Infective Endocarditis, See [[Endocarditis]]

[[Infertility]]

[[Inflammatory Bowel Disease]]

[[Influenza]]

Influenza Vaccination, See [[Immunisation]]

[[Inherited Disease]]

[[Innoculation Injury]]

Intermittent Claudication, See [[Peripheral Vascular Disease]]

[[Iron Deficiency (Anaemia)]]

[[Irritable Bowel Disease]]

Ischaemic Heart Disease, See [[Heart, Coronary Artery Disease]]

IVF, See [[Hormone Replacement Therapy]]

==J==

[[Jaundice]]

Juvenile Chronic Arthritis, See [[Juvenile Idiopathic Arthritis]]

[[Juvenile Idiopathic Arthritis]]

Juvenile Rheumatoid Arthritis, See [[Juvenile Idiopathic Arthritis]]

==K==

Kala-Azar, See [[Leishmaniasis]]

[[Kallman Syndrome]]

[[Kawasaki Disease]]

Key-Hole Surgery, See [[Surgery]]

[[Kidney Disease]]

Kidney Transplant, See [[Tissue Or Organ Transplant]]

[[Kidney, Single]]

Kienbock Disease, See [[Avascular Necrosis]]

[[Klinefelter Syndrome]]

Kyphosis, See [[Back Conditions]]

==L==

[[Labyrinthitis]]

Laminectomy, See [[Back Conditions]]

Laparoscopy, See [[Surgery]]

[[Laser Treatment]]

[[Lassa Fever]]

Latex Allergy, See [[Allergy]]

Left Branch Bundle Block, See [[Heart, Arrhythmia]]

[[Legionnaire's Disease]]

[[Leishmaniasis]]

[[Leptospirosis]]

Leukaemia, See [[Malignancy]]

[[Lichen Planus]]

[[Lichen Sclerosus]]

[[Lipoma]]

[[Liver Function, Abnormal]]

Low Blood Pressure, See [[Hypotension]]

Low Haemoglobin, See [[Anaemia]]

Low Platelets, See [[Thrombocytopenia]]

Lumbar Spine Abnormality, See [[Back Conditions]]

Lupus, See [[Systemic Lupus Erythematosus]]

[[Lupus Anticoagulant]]

[[Lyme Disease]]

[[Lymphadenopathy]]

[[Lymphoedema]]

[[Lymphogranuloma Venereum]]

==M==

[[Macrocytosis]]

[[Malaria]]

[[Malignancy]]

[[Malignant Hyperpyrexia]]

Malignant Melanoma, See [[Malignancy]]

Manic Depression, See [[Bipolar Affective Disorder]]

[[Marburg Fever]]

[[Marfan Syndrome]]

Mastectomy, See [[Surgery]]

[[Mastitis]]

Mastoid Operation, See [[Surgery]]

ME, See [[Myalgic Encephalomyelitis]]

Medical Trial, See [[Clinical Trial]]

[[Medications]]

[[Megaloblastic Anaemia]]

Membranous Glomerulonephritis, See [[Kidney Disease]]

[[Meniere Disease]]

Meningioma, See [[Brain Tumour]]

[[Meningitis]]

Meningoencephalitis, See [[Meningitis]]

[[Menopause]]

[[Menorrhagia]]

Metabolic Disease, Seee [[Inherited Disease]]

MGUS, See [[Monoclonal Gammopathy]]

Micropituitary Adenoma, See [[Pituitary Adenoma]]

[[Migraine]]

[[Miscarriage]]

Mitral Regurgitation, See [[Heart, Valve Disease]]

Mitral Stenosis, See [[Heart, Valve Disease]]

Mitral Valve Disease, See [[Heart, Valve Disease]]

[[Monoclonal Gammopathy]]

[[Mononeuritis]]

Mononucleosis, See [[Epstein-Barr Virus]]

[[Morphoea]]

Motor Neurone Disease, See [[Central Nervous System Disease]]

Motor Sensory Neuropathy, See [[Hereditary Motor Sensory Neuropathy]]

[[MRSA]]

MS, See [[Multiple Sclerosis]]

[[Multiple Sclerosis]]

[[Muscular Dystrophy]]

[[Muscular Dystrophy Carrier]]

[[Myalgic Encephalomyelitis]]

[[Myasthenia Gravis]]

[[Myelodysplasia]]

Myelofibrosis, See [[Myeloproliferative Neoplasm]]

[[Myeloproliferative Neoplasm]]

[[Myocarditis]]

Myoclonus, See [[Central Nervous System Disease]]

[[Myositis]]

Myotonia Congenita, See [[Muscular Dystrophy]]

Myotonic Dystrophy, See [[Muscular Dystrophy]]

Myxoedema, See [[Thyroid Disease]]

[[Myxoma]]

==N==

[[Narcolepsy]]

[[Needle Phobia]]

Needlestick Injury, See [[Innoculation Injury]]

Neotigason, See [[Acne]]

Nephrectomy (Kidney Removal), See [[Kidney, Single]]

Nephritis, See [[Kidney Disease]]

Nephropathy, See [[Kidney Disease]]

Nephrotic Syndrome, See [[Kidney Disease]]

[[Neurofibromatosis]]

Neuroma, See [[Brain Tumour]]

[[Neurosurgery]]

[[Neutropenia]]

[[Non Steroidal Anti-Inflammatory Drug]]

Non-Hodgkin Lymphoma, See [[Malignancy]]

Nose Bleed, See [[Epistaxis]]

NSAID, See [[Non Steroidal Anti-Inflammatory Drug]]

==O==

Obesity, See [[Weight]]

[[Obsessive Compulsive Disorder]]

[[Obstetric Cholestasis]]

[[Obstructive Sleep Apnoea]]

[[Ocular Surgery]]

[[Ocular Tissue Recipient]]

Oesophagitis, See [[Gastro-Oesophageal Reflux]]

[[Onchocerciasis]]

Operation, See [[Surgery]]

[[Optic Neuritis]]

[[Osgood Schlatter Disease]]

Osler-Weber-Rendu Disease, See [[Hereditary Haemorrhagic Telangiectasia]]

[[Osteoarthritis]]

[[Osteochondroma]]

Osteodystrophia Deformans, See [[Paget Disease]]

[[Osteogenesis Imperfecta]]

Osteoma, See [[Osteochondroma]]

[[Osteomalacia]]

[[Osteomyelitis]]

[[Osteopenia]]

[[Osteoporosis]]

[[Otosclerosis]]

[[Ovarian Cyst]]

==P==

Pacemaker, See [[Heart, Arrhythmia]]

[[Paget Disease]]

Paget Disease Of The Nipple, See [[Malignancy]]

[[Palindromic Rheumatism]]

[[Pancreatitis]]

Panic Attacks, See Anxiety Disorder

Paraplegia, See [[Disabled Volunteer]]

Paraprotein, See [[Monoclonal Gammopathy]]

[[Paratyphoid Fever]]

Parkinson Disease, See [[Central Nervous System Disease]]

[[Parvovirus]]

Patent Ductus Arteriosus, See [[Heart, Congenital Defect]]

Patent Foramen Ovale, See [[Heart, Congenital Defect]]

[[Pelvic Inflammatory Disease]]

[[Pemphigoid]]

[[Pemphigus]]

[[Peptic Ulcer]]

[[Pericarditis]]

[[Peripheral Neuropathy]]

[[Peripheral Vascular Disease]]

[[Peritonitis]]

[[Pernicious Anaemia]]

Peroneal Muscular Atrophy, See [[Hereditary Motor Sensory Neuropathy]]

[[Perthes Disease]]

[[Peyronie Disease]]

Phaeochromocytoma, See [[Malignancy]]

[[Phenylketonuria]]

[[Phlebitis]]

[[Pilonidal Sinus]]

[[Pituitary Adenoma]]

[[Pityriasis]]

[[Pleural Effusion]]

[[Pleurisy]]

[[Pneumonia]]

[[Pneumothorax]]

Polio, See [[Disabled Volunteer]]

Polyarteritis Nodosa, See [[Vasculitis]]

[[Polycystic Kidney Disease]]

[[Polycystic Ovarian Syndrome]]

[[Polycythaemia]]

Polycythemia Rubra Vera, See [[Myeloproliferative Neoplasm]]

[[Polymyalgia]]

[[Porphyria (All Types)]]

Positive Cervical Smear, See [[Cervical Carcinoma In-Situ]]

Post-Viral Fatigue Syndrome, See [[Myalgic Encephalomyelitis]]

[[POTS (Postural Orthostatic Tachycardia Syndrome)]]

[[Pre-Cancerous Cells]]

[[Pre-Eclampsia]]

[[Pregnancy]]

[[Prion-Associated Disease]]

[[Proctitis]]

[[Prolactinoma]]

Prolapsed Disc, See [[Back Conditions]]

[[Prostate, Enlarged]]

Prostatism, See [[Benign Prostatic Hyperplasia]]

Protein C Deficiency, See [[Thrombophilia]]

Protein S Deficiency, See [[Thrombophilia]]

Prothrombin Gene Mutation, See [[Thrombophilia]]

[[Psoriasis]]

Psoriatic Arthritis, See [[Psoriasis]]

Pulmonary Embolus, See [[Thrombosis]]

Pulmonary Stenosis / Regurgitation, See [[Heart, Congenital Defect]]

Pulmonary Valvotomy, See [[Heart, Valve Disease]]

[[Purpura]]

Pyelonephritis, See [[Kidney Disease]]

[[Pyloric Stenosis]]

[[Pyruvate Kinase Deficiency]]

==Q==

[[Q Fever]]

==R==

[[Rabies]]

[[Radionuclide Therapy]]

[[Radiotherapy]]

[[Raynaud Disease]]

[[Reactive Arthritis]]

[[Reflex Sympathetic Dystrophy]]

Reflux, See [[Gastro-Oesophageal Reflux]]

Reiter Syndrome, See [[Reactive Arthritis]]

Renal Colic, See [[Kidney Disease]]

Renal Disease, See [[Kidney Disease]]

[[Restless Legs Syndrome]]

[[Retinitis Pigmentosa]]

[[Retinoic Acid Derivatives]]

[[Reye Syndrome]]

[[Rheumatic Fever]]

[[Rheumatoid Arthritis]]

[[Rhinitis]]

Ricketts, See [[Disabled Volunteer]]

[[Rickettsial Infection]]

Right Bundle Branch Block, See [[Heart, Arrhythmia]]

[[Ringworm]]

River Blindness, See [[Onchocerciasis]]

Roaccutane, See [[Acne]]

Rocky Mountain Spotted Fever, See [[Rickettsial Infection]]

Rodent Ulcer, See [[Basal Cell Carcinoma]]

[[Rosacea]]

==S==

Sacroiliac Joint Problems, See [[Back Conditions]]

Sandhoff Disease, See [[Inherited Disease]]

[[Sarcoidosis]]

[[Scarlet Fever]]

Scheuermann Disease, See [[Back Conditions]]

[[Schistosomiasis]]

[[Schizophrenia]]

Schwannoma, See [[Acoustic Neuroma]]

Sciatica, See [[Back Conditions]]

[[Scleroderma]]

Scoliosis, See [[Back Conditions]]

[[Sebaceous Cyst]]

[[Seborrhoeic Dermatitis]]

Seizures, See [[Epilepsy]]

[[Septicaemia]]

Sex Change, See [[Gender Reassignment]]

[[Sexual Orientation]]

[[Sexually Transmitted Diseases]]

Shingles, See [[Chicken Pox]]

Shwachman-Diamond Syndrome, See [[Inherited Disease]]

[[Sickle Cell Disease]]

[[Sickle Cell Trait]]

[[Simple Cyst]]

[[Situs Inversus]]

[[Sjogren’s Syndrome]]

Sleeping Sickness, See [[African Trypanosomiasis]]

Smear - Abnormal Cervical, See [[Cervical Carcinoma In-Situ]]

[[South American Trypanosomiasis]]

Spasmodic Torticollis, See [[Back Conditions]]

Spherocytosis, See [[Hereditary Spherocytosis]]

[[Spina Bifida]]

Spinal Fusion, See [[Back Conditions]]

Spinal Muscular Atrophy, See [[Inherited Disease]]

Spinal Stenosis, See [[Back Conditions]]

[[Spitz Naevus]]

[[Splenectomy]]

Spondylolisthesis, See [[Back Conditions]]

Spondylosis, See [[Back Conditions]]

Spot Baldness, See [[Alopecia Areata]]

Spots, See [[Acne]]

[[Steroid Treatment]]

[[Stevens-Johnson Syndrome]]

Stickler Syndrome, See [[Inherited Disease]]

[[Still Disease]]

[[Stroke]]

[[Subarachnoid Haemorrhage]]

[[Subdural Haematoma]]

[[Subglottic Stenosis]]

Superficial Thrombophlebitis, See [[Thrombosis]]

Supraventricular Tachycardia, See [[Heart, Arrhythmia]]

[[Surgery]]

[[Suxamethonium Allergy]]

Sydenham Chorea, See [[Rheumatic Fever]]

[[Syphilis]]

[[Syringomyelia]]

[[Systemic Lupus Erythematosus]]

==T==

Tachycardia, See [[Heart, Arrhythmia]]

Takayasu Arteritis, See [[Vasculitis]]

Tattoo, See [[Body Piercing]]

Tay Sachs Disease, See [[Inherited Disease]]

Temporal Arteritis, See [[Vasculitis]]

Temporal Lobectomy, See [[Neurosurgery]] and [[Epilepsy]]

Termination Of Pregnancy, See [[Pregnancy]] and [[Surgery]]

Testosterone Injections, See [[Hormone Replacement Therapy]] and [[Addiction and Drug Abuse]]

Tetralogy Of Fallot, See [[Heart, Congenital Defect]]

Tetraplegia, See [[Disabled Volunteer]]

Thalassaemia Major, See [[Haemoglobin Disorder]]

Thalassaemia Trait (Minor), See [[Haemoglobin Disorder]]

[[Thoracic Outlet Syndrome]]

Thrombocythemia, See [[Thrombocytosis]]

[[Thrombocytopenia]]

[[Thrombocytosis]]

[[Thrombophilia]]

Thrombophlebitis, See [[Thrombosis]]

[[Thrombosis]]

Thrush, See [[Candida Infection]]

[[Thyroid Disease]]

Thyrotoxicosis, See [[Thyroid Disease]]

Tick Typhus, See [[Rickettsial Infection]]

[[Tissue Or Organ Transplant]]

[[Toxoplasmosis]]

[[Transfusion]]

Transient Ischaemic Attack (TIA), See [[Stroke]]

[[Transsexual]]

Treacher-Collins Syndrome, See [[Inherited Disease]]

Trial, See [[Clinical Trial]]

Tricuspid Regurgitation, See [[Heart, Valve Disease]]

Tricuspid Stenosis, See [[Heart, Valve Disease]]

[[Trigeminal Neuralgia]]

Trypanosoma Cruzi Infection, See [[South American Trypanosomiasis]]

[[Tuberculosis]]

[[Turner Syndrome]]

[[Typhoid]]

==U==

Ulcerative Colitis, See [[Inflammatory Bowel Disease]]

[[Urticaria]]

Uterine Fibroid, See [[Fibroids]]

Uveitis, See [[Eye Disease]]

==V==

Vaccine, See [[Immunisation]]

Vaccination, See [[Immunisation]]

Varicella Zoster, See [[Chicken Pox]]

[[Varicose Veins]]

[[Vasculitis]]

[[Vasovagal Attack]]

[[Venesection]]

Ventricular Septal Defect, See [[Heart, Congenital Defect]]

Vestibular Schwannoma, See [[Acoustic Neuroma]]

Visceral Leishmaniasis, See [[Leishmaniasis]]

[[Vitiligo]]

Von Recklinghausen Disease, See [[Neurofibromatosis]]

Von Willebrand Disease, See [[Bleeding Disorder]]

==W==

Warts, See [[Human Papilloma Virus]]

Wegener Granulomatosis, See [[Vasculitis]]

[[Weight]]

Weil Disease, See [[Leptospirosis]]

Werdnig-Hoffmann Disease, See [[Inherited Disease]]

[[West Nile Virus]]

[[Wilson Disease]]

Wolff-Parkinson-White Syndrome, See [[Heart, Arrhythmia]]

==X==

==Y==

[[Yaws]]

Yellow Fever, See [[Infection, Acute]]

Yellow Fever Vaccine, See [[Immunisation]]

==Z==

=Appendix 1 - Haematologic and biochemical testing at donor medical=

'''The following haematological and biochemical tests are performed at the donor medical:'''

Full blood count

Urea and Electrolytes

Liver function tests

Bone function tests

Cholesterol

Random glucose

Coagulation screen (PT, APTT and fibrinogen)

ABO and Rh blood grouping

Pregnancy test (B-HCG), if relevant

=Appendix 2 - Infectious disease marker testing at ET/CT and donor medical=

'''The following infectious disease markers are tested for all donors at the donor medical:'''

HIV (P24 antigen and antibody)

Hepatitis B (surface antigen and core antibody)

Hepatitis C (antibody and RNA)

HTLV I+II (antibody)

Syphilis (antibody)

Toxoplama (antibody)

EBV (VCA/NA IgG)

CMV (IgG)

Varicella (IgG)

'''The following infectious disease markers may be tested if a relevant travel history is given by the donor, at the discretion of the harvest physician or Anthony Nolan medical officer:'''

Malarial antigen/antibodies

T.cruzi (Chagas disease) antibodies

West nile virus NAT

=Appendix 3 - Other investigations at donor medical=

Electrocardiogram (ECG)

Chest X-ray

=Appendix 4 - Special consideration for donors in the Armed Forces=

'''Guidance for Armed Forces donors'''

It is recognised that members of the Armed Forces will need to get permission from the Commanding Officer prior to donation. Certain occupations within the MOD, such as aircrew within the RAF, will not allow donation by bone marrow harvest unless it is to a family member, although peripheral blood stem cell donation is permitted.

As a consequence, members of the Armed Forces are permitted to join the register as ‘PBSC only’ if there are concerns about the impact of bone marrow harvest on their ability to fulfil their role, or concerns about possible impact on their career.