MOSQUITO-BORNE VIRUS - Revision history

Natalie.Murray@anthonynolan.org: /* Guidance */

2026-08-11T09:53:49Z

Guidance

Natalie.Murray@anthonynolan.org: /* Guidance */

2026-08-11T09:50:12Z

Guidance

Natalie.Murray@anthonynolan.org: /* Guidance */

2026-08-11T09:49:30Z

Guidance

Natalie.Murray@anthonynolan.org: /* Definition */

2026-08-11T09:48:44Z

Definition

Natalie.Murray@anthonynolan.org: /* Definition */

2026-08-11T09:48:31Z

Definition

Natalie.Murray@anthonynolan.org: /* Acceptability at CT / Work-Up */

2026-08-11T09:47:48Z

Acceptability at CT / Work-Up

Natalie.Murray@anthonynolan.org: Created page with " ==Definition== Dengue Virus Chikungunya Virus Zika Virus, also see Zika Virus ==Acceptability at Recruitment== QUALIFIED - see below ==Acceptability at CT / Work-Up=..."

2026-08-11T09:45:56Z

Created page with " ==Definition== Dengue Virus Chikungunya Virus Zika Virus, also see Zika Virus ==Acceptability at Recruitment== QUALIFIED - see below ==Acceptability at CT / Work-Up=..."

New page

==Definition==

Dengue Virus

Chikungunya Virus

Zika Virus, also see [[Zika Virus]]

==Acceptability at Recruitment==
QUALIFIED - see below

==Acceptability at CT / Work-Up==
QUALIFIED - see below

==Individual at Risk==
Recipient

==Explanation of Condition==

'''Chikungunya Virus'''

Chikungunya is an alpha virus that can cause a wide spectrum of disease. This may range from no or minimal symptoms to death. Most commonly it causes arthritis (typically in the knee, ankle and small joints of the extremities), high fever and a maculopapular rash. It is geographically widespread but since 2005 it has reached epidemic proportions in parts of India and islands in the Indian Ocean. It is known to be spread by blood in symptomatic cases and on theoretical grounds could be spread by transfusion and transplantation of tissues and organs from people with pre-symptomatic or asymptomatic disease. A number of visitors returning from endemic areas to the UK have been diagnosed with this infection.

'''Dengue Virus'''

Dengue Virus is a flavivirus that typically gives rise to abrupt high fever with a range of accompanying symptoms. Dengue fever (DF) is the most common arthropod borne disease worldwide. Dengue is currently considered endemic in approximately 128 countries. Overall, 15-90% of cases may have an asymptomatic course of infection, but clinical presentation varies with age group. However there is a risk of change in disease presentation and potential for increased incidence of more severe disease in older age groups due to cocirculation of different dengue types and emergence of new types in endemic areas patterns.

'''Zika virus'''

Zika virus is a flavivirus that is transmitted to humans through the bite of a carrier mosquito. Zika infection is a rapid acute infection that in the majority of cases is asymptomatic or has very mild general symptoms. A small number of cases may have more apparent symptoms but hospitalisation is rare. Zika infection may be mistaken for Chikungunya or Dengue infections as the virus often co-circulate.

For yellow fever, see [[yellow fever]].

==Guidance==

See www.transfusionguidelines.org for up-to-date guidance

The following applies to all tropical viruses

===RECRUITMENT===

ACCEPT - if more than 4 weeks from a donor's return from a Tropical Virus Risk area, and the donor has had neither symptoms nor evidence of infection

DEFER - for 6 months '''IF''' it is less than six months from a donor's return from a Tropical Virus endemic area and the donor has been diagnosed or has a history of symptoms suggestive of infection whilst there or following their return to the UK.

===VT/WORK-UP===

ACCEPTABLE - May donate if more than 4 weeks from a donor's return from a Tropical Virus Risk area, and the donor has had neither symptoms nor evidence of infection

DEFER - If it is less than six months from a donor's return from a Tropical Virus Risk endemic area and the donor has been diagnosed or has a history of symptoms suggestive of a tropical virus infection whilst there or following their return to the UK. This period may be shortened at the discretion of the transplant centre following discussion.

See also [[Zika Virus]] Donors are excluded from donation if they have had sex less than 28 days ago with someone who has had a confirmed Zika Virus infection in the 3 months preceding the sexual contact

'''Where NAT testing is available''' this can be undertaken in discussion with MO and TC if it is i) less than 4 weeks from a donor's return from a tropical virus endemic area ii) less than 6 months from a donors return and they have a history of symptoms suggestive of a tropical virus.

===Version===

Version 1.0

11th August 2026

← Older revision		Revision as of 09:53, 11 August 2026
Line 40:		Line 40:

	The following applies to all mosquito-borne viruses		The following applies to all mosquito-borne viruses
		+
		+	See [[MOSQUITO-BORNE VIRUS - ALERTS]] for up to date alerts.

	===RECRUITMENT===		===RECRUITMENT===

@@ Line 3: / Line 3: @@
 Chikungunya Virus, also known as CHIKV
 Dengue Virus, also known as Dengue Fever
 Yellow Fever, also known as YF
 Zika Virus, also known as ZIKV, and Zika Virus Fever [[Zika Virus]]

@@ Line 2: / Line 2: @@
 ==Definition==
-Dengue Virus
+Chikungunya Virus, also known as CHIKV
+Dengue Virus, also known as Dengue Fever
-Chikungunya Virus
+Yellow Fever, also known as YF
+Zika Virus, also known as ZIKV, and Zika Virus Fever [[Zika Virus]]
 ==Acceptability at Recruitment==

@@ Line 37: / Line 37: @@
 ==Guidance==
-See www.transfusionguidelines.org for up-to-date guidance
+https://www.jpac.org.uk/guidelines/bm/index/mosquito-borne-viruses/ for up-to-date guidance
-The following applies to all tropical viruses
+The following applies to all mosquito-borne viruses
 ===RECRUITMENT===

@@ Line 56: / Line 56: @@
 See also [[Zika Virus]]  Donors are excluded from donation if they have had sex less than 28 days ago with someone who has had a confirmed Zika Virus infection in the 3 months preceding the sexual contact
-'''Where NAT testing is available''' this can be undertaken in discussion with MO and TC if it is i) less than 4 weeks from a donor's return from a tropical virus endemic area ii) less than 6 months from a donors return and they have a history of symptoms suggestive of a tropical virus.
+'''Where NAT testing is available''' this can be undertaken in discussion with MO and TC if it is i) less than 4 weeks from a donor's return from a tropical virus endemic area ii) less than 6 months from a donors return and they have a history of symptoms suggestive of a mosquito-borne virus.
 ===Version===

@@ Line 11: / Line 11: @@
 QUALIFIED - see below
-==Acceptability at CT / Work-Up==
+==Acceptability at VT / Work-Up==
 QUALIFIED - see below