Hormone Replacement Therapy

Acceptability at Recruitment

QUALIFIED

Acceptability at CT / Work-Up

QUALIFIED

Individual at Risk

Recipient

Explanation of Condition

Many conditions require hormone replacement. Today, most hormones are recreated synthetically in laboratories, and thus have negligible risk of carrying infectious organisms. However, some are still derived from human or animal tissue.

Those derived from human pituitary tissue are no longer used, but people who received them before variant CJD was identified are at risk of having contracted the disease, and thus must not donate.

There is considerable debate about the risk of hormones derived from human urine (usually HCG from pregnant women), but this risk is thought to be extremely small.

Guidance

Acceptable if entirely synthetic or recombinant hormone used.

Unacceptable if derived from human pituitary tissue.

If derived from human urine, accept at recruitment and inform transplant centre at CT.

Discuss individual cases with MO if required.

Pseudonyms or Related Conditions

Fertility treatment

HRT

Growth Hormone

Version

Version 1, Edition 1

Date of Last Update

15th June 2012