Difference between revisions of "Allergy"
| (2 intermediate revisions by 2 users not shown) | |||
| Line 5: | Line 5: | ||
==Individual at Risk== | ==Individual at Risk== | ||
| − | Donor / Recipient | + | Donor / Recipient |
| + | ==Guidance at RECRUITMENT/VT/WORK-UP== | ||
| − | ==Guidance at | + | === Guidance at recruitment === |
| − | ===Latex=== | + | Accept |
| + | |||
| + | === Guidance at VT === | ||
| + | |||
| + | ====Latex==== | ||
UNACCEPTABLE if anaphylaxis (life-threatening) or widespread allergy (i.e. rash all over the skin) to latex. | UNACCEPTABLE if anaphylaxis (life-threatening) or widespread allergy (i.e. rash all over the skin) to latex. | ||
| Line 16: | Line 21: | ||
ACCEPTABLE if mild localised contact allergy to latex (e.g. a rash on the hands from wearing latex gloves). | ACCEPTABLE if mild localised contact allergy to latex (e.g. a rash on the hands from wearing latex gloves). | ||
| − | ===Anaesthetic=== | + | ====Anaesthetic==== |
UNACCEPTABLE if life-threatening or other severe allergy to any anaesthetic agent. However, other adverse effects (such as nausea, vomiting, fatigue) may be acceptable. | UNACCEPTABLE if life-threatening or other severe allergy to any anaesthetic agent. However, other adverse effects (such as nausea, vomiting, fatigue) may be acceptable. | ||
| − | ===Other allergy=== | + | ====Other allergy==== |
ACCEPTABLE at the discretion of the assessing physician. Donors with multiple severe allergies, particularly with a history of anaphylaxis to more than one allergen should not donate. | ACCEPTABLE at the discretion of the assessing physician. Donors with multiple severe allergies, particularly with a history of anaphylaxis to more than one allergen should not donate. | ||
| Line 29: | Line 34: | ||
Inform transplant centre AND collection centre of any allergy, including hayfever. | Inform transplant centre AND collection centre of any allergy, including hayfever. | ||
| − | ===Justification for guidance=== | + | ====Justification for guidance==== |
During donation donors are exposed to a number of potential allergens, including G-CSF, anaesthetic agents and latex. There is a possibility of transfer of allergy to the recipient. | During donation donors are exposed to a number of potential allergens, including G-CSF, anaesthetic agents and latex. There is a possibility of transfer of allergy to the recipient. | ||
Latest revision as of 12:32, 30 June 2025
Contents
Condition
Any abnormal immune-mediated reaction to a drug or other external stimulus, such as rash, tongue-swelling, and difficulty breathing.
Individual at Risk
Donor / Recipient
Guidance at RECRUITMENT/VT/WORK-UP
Guidance at recruitment
Accept
Guidance at VT
Latex
UNACCEPTABLE if anaphylaxis (life-threatening) or widespread allergy (i.e. rash all over the skin) to latex.
ACCEPTABLE if mild localised contact allergy to latex (e.g. a rash on the hands from wearing latex gloves).
Anaesthetic
UNACCEPTABLE if life-threatening or other severe allergy to any anaesthetic agent. However, other adverse effects (such as nausea, vomiting, fatigue) may be acceptable.
Other allergy
ACCEPTABLE at the discretion of the assessing physician. Donors with multiple severe allergies, particularly with a history of anaphylaxis to more than one allergen should not donate.
ACCEPTABLE if currently undergoing desensitisation therapy.
Inform transplant centre AND collection centre of any allergy, including hayfever.
Justification for guidance
During donation donors are exposed to a number of potential allergens, including G-CSF, anaesthetic agents and latex. There is a possibility of transfer of allergy to the recipient.
Version
Version 1. Edition 1
9 June 2016
References
Tulpule S, Shaw BE, Makoni P, Little AM, Madrigal JA, Goldman JM. Severe allergic reaction with anaphylaxis to G-CSF (lenograstim) in a healthy donor. Bone Marrow Transplant 2009; 44(2): 129-30.
Hallstrand TS, Sprenger JD, Agosti JM, Longton GM, Witherspoon RP, Henderson WR, Jr. Long-term acquisition of allergen-specific IgE and asthma following allogeneic bone marrow transplantation from allergic donors. Blood 2004; 104(10): 3086-90.
Notes
Version
Version 1, Edition 1
Date of Last Update
15th June 2012
