Thrombophilia: Difference between revisions

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QUALIFIED
QUALIFIED


==Acceptability at CT / Work-Up==
==Acceptability at VT / Work-Up==
QUALIFIED
QUALIFIED


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==Guidance==
==Guidance==
====Unacceptable====
====Unacceptable====
Diagnosed thrombophilia in association with at least one episode of thrombosis;
Diagnosed thrombophilia in association with at least one episode of thrombosis (Blood Clot);


High risk thrombophilia (protein C, protein S or antithrombin deficiency)  '''even''' if the donor has not suffered from thrombosis;
Diagnosed high risk thrombophilia (protein C, protein S or antithrombin deficiency)  '''even''' if the donor has not suffered from thrombosis (Blood Clot);


Diagnosed [[Anti-Phospholipid Syndrome]]
Diagnosed [[Anti-Phospholipid Syndrome]]
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====Acceptable====
====Acceptable====


Low risk thrombophilia (Factor V Leiden, Prothrombin 20210 mutation) with no documented history of thrombosis
Diagnosed low risk thrombophilia (Factor V Leiden, Prothrombin 20210 mutation) of donor has no history of thrombosis (blood clot)


Family history of thrombosis with any thrombophilia other than protein C, protein S or antithrombin deficiency.
Family history of thrombosis with protein C, protein S or antithrombin deficiency is unacceptable. Family history of thrombosis with any thrombophilia other than protein C, protein S or antithrombin deficiency is acceptable.


==Pseudonyms or Related Conditions==
==Pseudonyms or Related Conditions==
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==Version==
==Version==
Version 1, Edition 1
Version 1, Edition 2


====Date of Last Update====
====Date of Last Update====
9 June 2016
9 June 2016

Latest revision as of 14:26, 12 August 2025

Acceptability at Recruitment

QUALIFIED

Acceptability at VT / Work-Up

QUALIFIED

Individual at Risk

Donor

Explanation of Condition

A variety of conditions predisposing people to blood clots (thrombosis).

See also Thrombophilia

Guidance

Unacceptable

Diagnosed thrombophilia in association with at least one episode of thrombosis (Blood Clot);

Diagnosed high risk thrombophilia (protein C, protein S or antithrombin deficiency) even if the donor has not suffered from thrombosis (Blood Clot);

Diagnosed Anti-Phospholipid Syndrome

Acceptable

Diagnosed low risk thrombophilia (Factor V Leiden, Prothrombin 20210 mutation) of donor has no history of thrombosis (blood clot)

Family history of thrombosis with protein C, protein S or antithrombin deficiency is unacceptable. Family history of thrombosis with any thrombophilia other than protein C, protein S or antithrombin deficiency is acceptable.

Pseudonyms or Related Conditions

Protein C deficiency

Protein S deficiency

Factor V Leiden

Prothrombin mutation

Lupus anticoagulant

Antiphospholipid antibody

High factor VIII level

Antithrombin deficiency

Homocysteinaemia/MTHFR mutation

Version

Version 1, Edition 2

Date of Last Update

9 June 2016