Difference between revisions of "Pre-Malignant Conditions"
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===Cervical Intraepithelial Neoplasia (CIN)===  | ===Cervical Intraepithelial Neoplasia (CIN)===  | ||
| − | Acceptable at recruitment and VT if spontaneous resolution, or removed surgically or with cryo/laser therapy, with histologically confirmed Cervical Intra-epithelial Neoplasia (CIN) 1,2 or 3, and donor back on routine national screening programme.    | + | RECRUITMENT AND VT - Acceptable at recruitment and VT if spontaneous resolution, or removed surgically or with cryo/laser therapy, with histologically confirmed Cervical Intra-epithelial Neoplasia (CIN) 1,2 or 3, and donor back on routine national screening programme.  | 
| + | ===Familial Adenomatous Polyposis===  | ||
| − | ===  | + | RECRUITMENT - Not Acceptable   | 
| + | |||
| + | VT - If undergoing regular screening programme and no features of malignant change may be acceptable. Discuss with MO and TC  | ||
| + | |||
| + | ===PALB2===  | ||
| + | Associated with a high risk of breast cancer and a moderately increased risk of ovarian, pancreatic and possibly other cancers)   | ||
| + | |||
| + | Recruitment - Unacceptable   | ||
| − | + | VT - Acceptable:    | |
| − | If   | + | * If compliant with advised regular screening programme (e.g. for women very high risk breast cancer schedule) and no features/symptoms of malignant change – inform/consult MO    | 
| + | *   | ||
| + | * All women should have a breast examination at medical   | ||
| + | *   | ||
| + | * Inform TC if under a screening/surveillance programme  | ||
==Version==	  | ==Version==	  | ||
Latest revision as of 14:22, 26 August 2025
Contents
Acceptability at Recruitment
NOT ACCEPTABLE
Acceptability at CT / Work-Up
QUALIFIED, See below
Individual at Risk
Recipient
Explanation of Condition
Inherited conditions predisposing to risk of developing or transforming to malignancy
Guidance
Dependent on diagnosis, see below
BRCA1/BRCA2 Mutation
RECRUITMENT - Not Acceptable
VT - Acceptable if undergoing recommended screening. Inform TC at VT
All women should have a breast examination at medical
Cervical Intraepithelial Neoplasia (CIN)
RECRUITMENT AND VT - Acceptable at recruitment and VT if spontaneous resolution, or removed surgically or with cryo/laser therapy, with histologically confirmed Cervical Intra-epithelial Neoplasia (CIN) 1,2 or 3, and donor back on routine national screening programme.
Familial Adenomatous Polyposis
RECRUITMENT - Not Acceptable
VT - If undergoing regular screening programme and no features of malignant change may be acceptable. Discuss with MO and TC
PALB2
Associated with a high risk of breast cancer and a moderately increased risk of ovarian, pancreatic and possibly other cancers)
Recruitment - Unacceptable
VT - Acceptable:
- If compliant with advised regular screening programme (e.g. for women very high risk breast cancer schedule) and no features/symptoms of malignant change – inform/consult MO
 - All women should have a breast examination at medical
 - Inform TC if under a screening/surveillance programme
 
Version
Version 1, Edition 1
Date of Last Update
1 June 2016