Difference between revisions of "Heart, Congenital Defect"
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Surgically corrected simple defect (ASD, VSD, PFO), or uncorrected small asymptomatic ventricular septal defect. | Surgically corrected simple defect (ASD, VSD, PFO), or uncorrected small asymptomatic ventricular septal defect. | ||
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| + | Surgically corrected PDA provided no further symptoms or related cardiac problems. Discuss with cardiac team if still under follow-up | ||
===Unacceptable=== | ===Unacceptable=== | ||
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Any complex congenital defect, such as Tetralogy of Fallot (TOF), Transposition of the Great Arteries (TGA), Anomalous pulmonary circulation. | Any complex congenital defect, such as Tetralogy of Fallot (TOF), Transposition of the Great Arteries (TGA), Anomalous pulmonary circulation. | ||
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| + | Coarctation of the aorta, including if repaired. | ||
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Discuss each case with medical officer. | Discuss each case with medical officer. | ||
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==Pseudonyms or Related Conditions== | ==Pseudonyms or Related Conditions== | ||
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==Version== | ==Version== | ||
| − | Version 1, Edition | + | Version 1, Edition 3 |
====Date of Last Update==== | ====Date of Last Update==== | ||
| − | + | 3rd September 2024 | |
Latest revision as of 14:47, 9 September 2024
Contents
Acceptability at Recruitment
QUALIFIED
Acceptability at CT / Work-Up
QUALIFIED
Individual at Risk
Donor
Explanation of Condition
This covers a wide range of heart abnormalities that are, by definition, present from birth. The most common defects are simple 'hole-in-the-heart' abnormalities, such as an atrial septal defect (ASD), patent foramen ovale (PFO) or ventricular septal defect (VSD).
Apheresis and bone marrow harvest may increase the risk of small clots passing across such a defect in the heart and into the circulation of the brain, leading to a stroke. With a normal heart, these clots would be harmlessly filtered out by the lungs. In addition, there is a theoretical risk of infection in the heart (endocarditis), particularly if a central venous catheter is inserted.
Many people with congenital heart disease or with previous heart surgery take long-term antibiotics to prevent endocarditis. However, the evidence to support this use is weak, and there is no evidence to support their use in people with simple congenital defects such as an atrial or ventricular septal defect. As a result, this should not be used as a criteria to accept or decline a donor.
In addition, the latest NICE (National Institute of Clinical Evidence) guidance suggests that there is no increased risk of infectious endocarditis is those with a simple atrial septal defect, or surgically corrected ASD, VSD or PDA following invasive procedures.
Guidance
Acceptable
Surgically corrected simple defect (ASD, VSD, PFO), or uncorrected small asymptomatic ventricular septal defect.
Surgically corrected PDA provided no further symptoms or related cardiac problems. Discuss with cardiac team if still under follow-up
Unacceptable
Uncorrected atrial septal defect (ASD) or patent foramen ovale (PFO)
Large ventricular septal defect (VSD)
Any complex congenital defect, such as Tetralogy of Fallot (TOF), Transposition of the Great Arteries (TGA), Anomalous pulmonary circulation.
Coarctation of the aorta, including if repaired.
See also Heart, Valve Disease
Discuss each case with medical officer.
Pseudonyms or Related Conditions
Ventricular septal defect (VSD)
Atrial septal defect (ASD)
Patent foramen ovale (PFO)
Tetralogy of Fallot
Hole in the heart
Patent ductus arteriosus (PDA)
Transposition of the great vessels
Anomolous pulmonary venous return
Version
Version 1, Edition 3
Date of Last Update
3rd September 2024
