Difference between revisions of "Neutropenia"
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==Guidance== | ==Guidance== | ||
| − | + | If neutrophils < CC guidance suggest: | |
| + | |||
| + | Repeat FBC | ||
| + | |||
| + | Blood film | ||
| + | |||
| + | B12/folate | ||
| + | |||
| + | Immunoglobulins | ||
| + | |||
| + | Autoimmune screen | ||
| + | |||
| + | Review viral screen | ||
| + | |||
| + | If donor ethnicity suggestive of benign ethnic neutropenia (BEN), also send for duffy antigen testing. Duffy null phenotype (Fy(A-b-)) is supportive of BEN. | ||
| + | |||
| + | If level persistently 1.5 - 1.8 and no clear cause discuss with TC prior to medical clearance. Suggest TC consider alternative donor. | ||
| + | |||
| + | If level persistently < 1.5 (but TC keen to proceed) discuss with Senior Medical Officer prior to medical clearance | ||
Acceptable if benign ethnic neutropenia, as long as absolute neutrophil count is >1.0x10^9/L. | Acceptable if benign ethnic neutropenia, as long as absolute neutrophil count is >1.0x10^9/L. | ||
| Line 24: | Line 42: | ||
==Version== | ==Version== | ||
| − | Version 1, Edition | + | Version 1, Edition 2 |
====Date of Last Update==== | ====Date of Last Update==== | ||
| − | + | 10th October 2024 | |
Latest revision as of 13:31, 3 November 2025
Contents
Acceptability at Recruitment
QUALIFIED
Acceptability at CT / Work-Up
QUALIFIED
Individual at Risk
Donor / Recipient
Explanation of Condition
Low neutrophil count.
Guidance
If neutrophils < CC guidance suggest:
Repeat FBC
Blood film
B12/folate
Immunoglobulins
Autoimmune screen
Review viral screen
If donor ethnicity suggestive of benign ethnic neutropenia (BEN), also send for duffy antigen testing. Duffy null phenotype (Fy(A-b-)) is supportive of BEN.
If level persistently 1.5 - 1.8 and no clear cause discuss with TC prior to medical clearance. Suggest TC consider alternative donor.
If level persistently < 1.5 (but TC keen to proceed) discuss with Senior Medical Officer prior to medical clearance
Acceptable if benign ethnic neutropenia, as long as absolute neutrophil count is >1.0x10^9/L.
Unacceptable if autoimmune neutropenia
Pseudonyms or Related Conditions
Benign Ethnic Neutropenia
Autoimmune Neutropenia
Version
Version 1, Edition 2
Date of Last Update
10th October 2024
