Difference between revisions of "Asthma"
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==Acceptability at Recruitment== | ==Acceptability at Recruitment== | ||
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| + | ACCEPT if condition is controlled with (daily) inhalers or non-steroidal oral medication (e.g. Monteleukast) | ||
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| + | DEFER if condition requires oral steroids or steroid sparing agents (e.g. Omalizumab) | ||
| + | |||
| + | if admitted to hospital with need for IV steroids or emergency care in the past 2 years. | ||
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| + | if ever been admitted to intensive care due to an asthma attack. | ||
==Acceptability at CT / Work-Up== | ==Acceptability at CT / Work-Up== | ||
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| + | <B>PBSC</B> | ||
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| + | ACCEPT if condition is controlled with (daily) inhalers or non-steroidal oral medication (e.g. monteleukast) | ||
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| + | DEFER if condition is poorly controlled and/or requires oral steroids or steroid sparing agents (e.g. Omalizumab) | ||
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| + | DISCUSS with MO if history of previous ICU admission. May be acceptable if single ICU admission in childhood, due to an obvious trigger and the donor's asthma is currently well controlled. | ||
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| + | <B>BM</B> | ||
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| + | MAY BE ACCEPTABLE if condition is controlled with (daily) inhalers or non-steroidal oral medication. | ||
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| + | For bone marrow harvest, asthma which has been mild and well-controlled for the past year does not require anaesthetic input. In all other cases, donors should have a pre-operative anaesthetic review. | ||
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| + | DEFER if condition is severe and/or requires oral steroids or steroid sparing agents | ||
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| + | <B> All donors </B> | ||
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| + | If a donor is unsuitable for bone marrow harvest, the requesting transplant centre must be informed that there will not be an option of rescue marrow harvest in the case of failed mobilization. | ||
==Individual at Risk== | ==Individual at Risk== | ||
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Asthmatics are at a higher risk from donation, and from general anaesthetic in particular. | Asthmatics are at a higher risk from donation, and from general anaesthetic in particular. | ||
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| + | Poorly controlled asthma is unacceptable because G-CSF can trigger a flare of asthma symptoms. | ||
==Guidance== | ==Guidance== | ||
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| − | + | Mild asthma is acceptable. However, the condition must be reassessed and evaluated in case of a HR/CT or work up request. The risk for exacerbation is increased if the condition is severe. | |
==Pseudonyms or Related Conditions== | ==Pseudonyms or Related Conditions== | ||
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==Version== | ==Version== | ||
| − | Version 1, Edition | + | Version 1, Edition 2 |
====Date of Last Update==== | ====Date of Last Update==== | ||
| − | + | 9 June 2016 | |
Latest revision as of 14:17, 16 September 2024
Contents
Acceptability at Recruitment
ACCEPT if condition is controlled with (daily) inhalers or non-steroidal oral medication (e.g. Monteleukast)
DEFER if condition requires oral steroids or steroid sparing agents (e.g. Omalizumab)
if admitted to hospital with need for IV steroids or emergency care in the past 2 years.
if ever been admitted to intensive care due to an asthma attack.
Acceptability at CT / Work-Up
PBSC
ACCEPT if condition is controlled with (daily) inhalers or non-steroidal oral medication (e.g. monteleukast)
DEFER if condition is poorly controlled and/or requires oral steroids or steroid sparing agents (e.g. Omalizumab)
DISCUSS with MO if history of previous ICU admission. May be acceptable if single ICU admission in childhood, due to an obvious trigger and the donor's asthma is currently well controlled.
BM
MAY BE ACCEPTABLE if condition is controlled with (daily) inhalers or non-steroidal oral medication.
For bone marrow harvest, asthma which has been mild and well-controlled for the past year does not require anaesthetic input. In all other cases, donors should have a pre-operative anaesthetic review.
DEFER if condition is severe and/or requires oral steroids or steroid sparing agents
All donors
If a donor is unsuitable for bone marrow harvest, the requesting transplant centre must be informed that there will not be an option of rescue marrow harvest in the case of failed mobilization.
Individual at Risk
Donor
Explanation of Condition
Constriction of the airways which may be triggered by external stimuli (such as cold air, pollen or pollution) or may be spontaneous. Usually controlled by a combination of bronchodilator inhalers (such as salbutamol) and steroid inhalers (such as beclometasone). More severe asthma may require tablet therapy such as theophylline, montelukast or steroids.
Asthmatics are at a higher risk from donation, and from general anaesthetic in particular.
Poorly controlled asthma is unacceptable because G-CSF can trigger a flare of asthma symptoms.
Guidance
Mild asthma is acceptable. However, the condition must be reassessed and evaluated in case of a HR/CT or work up request. The risk for exacerbation is increased if the condition is severe.
Pseudonyms or Related Conditions
Bronchospasm
Version
Version 1, Edition 2
Date of Last Update
9 June 2016
