Difference between revisions of "PrEP"

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==Explanation of Condition==
 
==Explanation of Condition==
Pre-Exposure Prophylaxis (PrEP) is used to prevent HIV infection  
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Pre-Exposure Prophylaxis (PrEP) is used to prevent HIV infection.
 +
The main risk associated with PrEP is that it can give false negative HIV results, meaning that early HIV infections are not picked up.
  
 
==Justification for guidance==
 
==Justification for guidance==

Revision as of 08:28, 1 August 2024

PrEP – Pre-Exposure Prophylaxis


Acceptability at Recruitment

Acceptable

Acceptability at CT / Work-Up

Guidelines around PrEP have recently changed. Instead of a three month deferral period, current guidance is to inform the TC of the PrEP and it is their discretion on whether a three month deferral period is required. If the TC feels that the risks of delaying the donation outweigh the risks of a falsely negative HIV result, then the deferral period can be shortened or dismissed.

Individual at Risk

Recipient

Explanation of Condition

Pre-Exposure Prophylaxis (PrEP) is used to prevent HIV infection. The main risk associated with PrEP is that it can give false negative HIV results, meaning that early HIV infections are not picked up.

Justification for guidance

PrEP may alter HIV testing, resulting in an unclear or negative result in HIV positive donors, with a potential risk of transmission of this virus to patients.

We care a lot about the health of our donors. If you've been using medications like PrEP or PEP to prevent HIV, it could affect the accuracy of HIV tests for up to 3 months after you stop using them (Seed et al, 2020 - [1]). Because of this, health authorities worldwide, including the UK, advise that if you've used PrEP or PEP in the last 3 months, you shouldn't donate.