Heart, Valve Disease

Acceptability at Recruitment

QUALIFIED

Acceptability at VT / Work-Up

QUALIFIED

Individual at Risk

Donor

Explanation of Condition

The heart valves ensure that blood flows in the right direction through the heart and out to the body or lungs. They may become disease, most commonly through age, but also as a result of infection, autoimmune disease, or because of congenital defects.

The use of prophylactic antibiotics is not based on evidence and should not be used to decide whether or not to accept a donor.

Guidance

Guidance at recruitment

Acceptable

Bicuspid valve without significant stenosis

Bicuspid aortic valve

Murmurs without any further information(e.g. systolic or flow murmur)

Minor valve defects

Leaky valve

Mild tricuspid regurgitation

Mitral valve prolapse

Guidance at VT

Acceptable

The following conditions may be acceptable if no ongoing medical care is required, including any medications, and there are no restrictions of activities of daily living:

Mitral valve prolapse in the absence of haemodynamically significant mitral regurgitation and QTc prolongation (obtain pre-operative anaesthetic review if bone marrow collection required)

Minor valve defects (such as mild tricuspid regurgitation) and innocent murmurs

Bicuspid aortic valve without significant stenosis

Unacceptable

Any valve replacement or balloon valvuloplasty

Any clinically significant valvular disease (either by symptoms or echocardiography)

Any congenital valvular stenosis other than biscuspid aortic valve.

Any other valve defect requiring ongoing clinical care or medication, or which causes any restriction in activities of daily living.

Pseudonyms or Related Conditions

Murmur

Leaky valve

Aortic stenosis

Aortic regurgitation

Mitral stenosis

Mitral regurgitation

Tricuspid stenosis

Tricuspid regurgitation

Pulmonary stenosis

Pulmonary regurgitation

Mitral valve prolapse

Ebstein anomaly

Version

Version 1, Edition 3

Date of Last Update

24th July 2025