Bleeding Disorder

From Anthony Nolan Medical Guidelines
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Acceptability at Recruitment

QUALIFIED

Acceptability at CT / Work-Up

QUALIFIED

Individual at Risk

Donor

Explanation of Condition

Most haemophilias are inherited disorders of blood clotting. They may be of varying severity, but generally prohibit bone marrow donation.

Some haemophilias are acquired during life, and may be transient.

Guidance

Discuss with medical officer.

Unacceptable if history of excessive spontaneous or provoked bleeding, or laboratory demonstrated severe or moderate haemophilia (including asymptomatic factor XI deficiency).

Female carriers of haemophilia A and B should be discussed with medical officer. Consider for PBSC only if bleeding risk thought to be negligeable and after liaison with haemophilia centre.

Not for central venous catheter insertion or bone marrow harvest.

Any degree of factor XII deficiency is acceptable as long as there is no history of thrombosis.

Pseudonyms or Related Conditions

Haemophilia A

Haemophilia B

Factor XIII, XI, VIII, VII or V Deficiency

Hypofibrinogenaemia

Dysfibrinogenaemia

Von Willebrand Disease

Platelet Function Defect

Platelet Disorder

Version

Version 1, Edition 1

Date of Last Update

15th June 2012