Migraine

Acceptability at Recruitment

QUALIFIED

Acceptability at CT / Work-Up

QUALIFIED

Individual at Risk

Donor

Explanation of Condition

Intermittent headaches associated with nausea and visual phenomena (aura), such as zig-zag lines or halos.

See also Migraine

Guidance

Guidance at registration

Unacceptable

Donors taking the following medications should not be accepted onto the register: Clonidine, Erenumab (Aimovig), Fremanezumab (Ajovy), Galcanezumab (Emgality).

Otherwise, acceptable.

Guidance at VT

Unacceptable

Severe, having more than two attacks per month

Requires clonidine as prophylaxis (preventative medication)

Monoclonal antibodies are used for migraine prophylaxis. In the UK, erenumab (aimovig), fremanezumab (ajovy), galcanezumab (emgality) are the monoclonal antibodies licensed for use. Past or current use of monoclonal antibodies is a permanent exclusion.

Acceptable

Uses pizotifen (Sanomigran) or beta-blocker as prophylaxis

Discuss with medical officer if unclear.

Version

Version 1, Edition 3

Date of Last Update

23 July 2025