Difference between revisions of "Bleeding Disorder"
m (Protected "Bleeding Disorder" ([edit=sysop] (indefinite) [move=sysop] (indefinite))) |
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==Guidance== | ==Guidance== | ||
Discuss with medical officer. | Discuss with medical officer. | ||
| + | |||
| + | <b> For known history: </b> | ||
Unacceptable if history of excessive spontaneous or provoked bleeding, or laboratory demonstrated severe or moderate haemophilia (including asymptomatic factor XI deficiency). | Unacceptable if history of excessive spontaneous or provoked bleeding, or laboratory demonstrated severe or moderate haemophilia (including asymptomatic factor XI deficiency). | ||
| Line 23: | Line 25: | ||
Any degree of factor XII deficiency is acceptable as long as there is no history of thrombosis. | Any degree of factor XII deficiency is acceptable as long as there is no history of thrombosis. | ||
| + | |||
| + | |||
| + | <b> For newly identified clotting abnormalities at medical: </b> | ||
| + | |||
| + | Assess the donor for personal and family history of excessive bleeding and bruising. | ||
| + | |||
| + | • Has the donor noticed any excessive bleeding – e.g. after injuries or cuts? | ||
| + | |||
| + | • Any issues with bleeding that was difficult to stop following an operation or tooth extraction? | ||
| + | |||
| + | • Does the donor experience nosebleeds? If so, how often do they happen, are the nosebleeds from one nostril or both, how long do they take to stop and what measures are needed for the nosebleeds to stop? | ||
| + | |||
| + | • Has the donor ever experienced significant joint swelling? (i.e. potentially bleeding into their joints). | ||
| + | |||
| + | • Has the donor noticed any easy bruising? | ||
| + | |||
| + | • Are there any family members with bleeding disorders, or abnormal bleeding or bruising? | ||
| + | |||
| + | |||
| + | If the history is reassuring, repeat the coagulation screen as spurious results can occur. | ||
| + | |||
| + | If the clotting screen remains abnormal, discussion is needed with a haematology consultant specialised in bleeding disorders on whether the donor can be cleared. | ||
==Pseudonyms or Related Conditions== | ==Pseudonyms or Related Conditions== | ||
Revision as of 15:30, 27 June 2024
Contents
Acceptability at Recruitment
QUALIFIED
Acceptability at CT / Work-Up
QUALIFIED
Individual at Risk
Donor
Explanation of Condition
Most haemophilias are inherited disorders of blood clotting. They may be of varying severity, but generally prohibit bone marrow donation.
Some haemophilias are acquired during life, and may be transient.
Guidance
Discuss with medical officer.
For known history:
Unacceptable if history of excessive spontaneous or provoked bleeding, or laboratory demonstrated severe or moderate haemophilia (including asymptomatic factor XI deficiency).
Female carriers of haemophilia A and B should be discussed with medical officer. Consider for PBSC only if bleeding risk thought to be negligeable and after liaison with haemophilia centre.
Not for central venous catheter insertion or bone marrow harvest.
Any degree of factor XII deficiency is acceptable as long as there is no history of thrombosis.
For newly identified clotting abnormalities at medical:
Assess the donor for personal and family history of excessive bleeding and bruising.
• Has the donor noticed any excessive bleeding – e.g. after injuries or cuts?
• Any issues with bleeding that was difficult to stop following an operation or tooth extraction?
• Does the donor experience nosebleeds? If so, how often do they happen, are the nosebleeds from one nostril or both, how long do they take to stop and what measures are needed for the nosebleeds to stop?
• Has the donor ever experienced significant joint swelling? (i.e. potentially bleeding into their joints).
• Has the donor noticed any easy bruising?
• Are there any family members with bleeding disorders, or abnormal bleeding or bruising?
If the history is reassuring, repeat the coagulation screen as spurious results can occur.
If the clotting screen remains abnormal, discussion is needed with a haematology consultant specialised in bleeding disorders on whether the donor can be cleared.
Pseudonyms or Related Conditions
Haemophilia A
Haemophilia B
Factor XIII, XI, VIII, VII or V Deficiency
Hypofibrinogenaemia
Dysfibrinogenaemia
Von Willebrand Disease
Platelet Function Defect
Platelet Disorder
Version
Version 1, Edition 1
Date of Last Update
15th June 2012
