Difference between revisions of "Bleeding Disorder"
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QUALIFIED | QUALIFIED | ||
| − | ==Acceptability at | + | ==Acceptability at VT / Work-Up== |
QUALIFIED | QUALIFIED | ||
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==Guidance== | ==Guidance== | ||
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| + | === Guidance at recruitment === | ||
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| + | Acceptable | ||
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| + | === Guidance at VT === | ||
Discuss with medical officer. | Discuss with medical officer. | ||
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Assess the donor for personal and family history of excessive bleeding and bruising. | Assess the donor for personal and family history of excessive bleeding and bruising. | ||
| − | + | *Do you have any bleeding symptoms such as frequent nose bleeds, bleeding from the back passage or bleeding from the gums? | |
| − | + | *Have you ever consulted a doctor or received treatment for prolonged or unusual bleeding e.g. with nosebleeds or minor wounds? | |
| − | + | *Do you experience bruises/haematomas larger than 2cm without trauma, or severe bruising after minor trauma? | |
| − | + | *Have you ever had surgery (major or minor) or any dental procedures? If yes - Have you ever experienced or been told you had prolonged or excessive bleeding after or during these procedures or required medical attention for this? | |
| − | + | *Is there anyone in your family who suffers from a bleeding disorder e.g. Haemophilia/Von Willebrand disease? | |
| − | + | If assigned female at birth: | |
| − | + | *Have you ever consulted a doctor or received treatment for heavy or prolonged menstrual periods (contraceptive pill, iron etc.)? | |
| − | + | *Have you given birth - If yes - Did you experience prolonged or excessive bleeding after delivery? | |
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| − | If the history is reassuring, repeat the coagulation screen as spurious results can occur. | + | If the history is reassuring, repeat the coagulation screen with relevant factor levels as spurious results can occur. |
| − | + | If APTT remains prolonged in isolation but factor levels are normal and there is no bleeding history - the donor can be cleared if the CC are in agreement. If there are concerns from the CC or regarding bleeding history discuss case with a clotting specialist. | |
==Pseudonyms or Related Conditions== | ==Pseudonyms or Related Conditions== | ||
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Platelet Disorder | Platelet Disorder | ||
==Version== | ==Version== | ||
| − | Version 1, Edition | + | Version 1, Edition 2 |
====Date of Last Update==== | ====Date of Last Update==== | ||
| − | + | 17th September 2025 | |
Latest revision as of 13:27, 17 September 2025
Contents
Acceptability at Recruitment
QUALIFIED
Acceptability at VT / Work-Up
QUALIFIED
Individual at Risk
Donor
Explanation of Condition
Most haemophilias are inherited disorders of blood clotting. They may be of varying severity, but generally prohibit bone marrow donation.
Some haemophilias are acquired during life, and may be transient.
Guidance
Guidance at recruitment
Acceptable
Guidance at VT
Discuss with medical officer.
For known history:
Unacceptable if history of excessive spontaneous or provoked bleeding, or laboratory demonstrated severe or moderate haemophilia (including asymptomatic factor XI deficiency).
Female carriers of haemophilia A and B should be discussed with medical officer. Consider for PBSC only if bleeding risk thought to be negligeable and after liaison with haemophilia centre.
Not for central venous catheter insertion or bone marrow harvest.
Any degree of factor XII deficiency is acceptable as long as there is no history of thrombosis.
For newly identified clotting abnormalities at medical:
Assess the donor for personal and family history of excessive bleeding and bruising.
- Do you have any bleeding symptoms such as frequent nose bleeds, bleeding from the back passage or bleeding from the gums?
- Have you ever consulted a doctor or received treatment for prolonged or unusual bleeding e.g. with nosebleeds or minor wounds?
- Do you experience bruises/haematomas larger than 2cm without trauma, or severe bruising after minor trauma?
- Have you ever had surgery (major or minor) or any dental procedures? If yes - Have you ever experienced or been told you had prolonged or excessive bleeding after or during these procedures or required medical attention for this?
- Is there anyone in your family who suffers from a bleeding disorder e.g. Haemophilia/Von Willebrand disease?
If assigned female at birth:
- Have you ever consulted a doctor or received treatment for heavy or prolonged menstrual periods (contraceptive pill, iron etc.)?
- Have you given birth - If yes - Did you experience prolonged or excessive bleeding after delivery?
If the history is reassuring, repeat the coagulation screen with relevant factor levels as spurious results can occur.
If APTT remains prolonged in isolation but factor levels are normal and there is no bleeding history - the donor can be cleared if the CC are in agreement. If there are concerns from the CC or regarding bleeding history discuss case with a clotting specialist.
Pseudonyms or Related Conditions
Haemophilia A
Haemophilia B
Factor XIII, XI, VIII, VII or V Deficiency
Hypofibrinogenaemia
Dysfibrinogenaemia
Von Willebrand Disease
Platelet Function Defect
Platelet Disorder
Version
Version 1, Edition 2
Date of Last Update
17th September 2025
