Difference between revisions of "Proteinuria"
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| − | Acceptability at Recruitment | + | |
| + | ==Acceptability at Recruitment== | ||
ACCEPTABLE | ACCEPTABLE | ||
| − | Acceptability at VT / Work-Up | + | ==Acceptability at VT / Work-Up== |
ACCEPTABLE | ACCEPTABLE | ||
| − | Individual at risk | + | ==Individual at risk== |
Donor | Donor | ||
| − | Explanation of Condition | + | |
| + | ==Explanation of Condition== | ||
Protein present in urine, found either from a urine dipstick test or a Microbiology, Culture & Sensitive (MC&S) test. | Protein present in urine, found either from a urine dipstick test or a Microbiology, Culture & Sensitive (MC&S) test. | ||
| − | Guidance | + | ==Guidance== |
| − | If | + | |
| − | + | If isolated proteinuria is detected, a urine albumin-to-creatinine ratio (ACR) test must be conducted. Proteinuria can be a sign of underlying kidney conditions such as IgA nephropathy or glomerulonephritis, both of which are often undiagnosed. Administration of granulocyte colony-stimulating factor (G-CSF) may worsen these conditions, which is the basis for this precaution. | |
| + | |||
| + | To be medically cleared for donation, the donor must have a negative urine protein test, or the ACR is <5 mg/mmol ensuring that kidney disease is unlikely. If proteinuria is present, the algorithm on the following link must be followed: | ||
| + | |||
| + | https://www.med-guidelines.org.uk/images/c/ca/Urine_algorithm.jpg | ||
For haematuria, please see [[haematuria]] | For haematuria, please see [[haematuria]] | ||
| − | Pseudonyms or Related Conditions | + | If both blood and protein are present in the urine, both urine ACR and a MC&S/ MSU must be tested. |
| + | |||
| + | ==Pseudonyms or Related Conditions== | ||
IgA Nephropathy | IgA Nephropathy | ||
| + | |||
Berger’s disease | Berger’s disease | ||
| + | |||
Glomerulonephritis | Glomerulonephritis | ||
| − | Version 1, Edition 1 | + | ==Version 1, Edition 1== |
| + | |||
| + | '''Date of Last Update | ||
| − | + | 14/07/2025''' | |
| − | 14/07/2025 | ||
Latest revision as of 12:15, 16 July 2025
Contents
Acceptability at Recruitment
ACCEPTABLE
Acceptability at VT / Work-Up
ACCEPTABLE
Individual at risk
Donor
Explanation of Condition
Protein present in urine, found either from a urine dipstick test or a Microbiology, Culture & Sensitive (MC&S) test.
Guidance
If isolated proteinuria is detected, a urine albumin-to-creatinine ratio (ACR) test must be conducted. Proteinuria can be a sign of underlying kidney conditions such as IgA nephropathy or glomerulonephritis, both of which are often undiagnosed. Administration of granulocyte colony-stimulating factor (G-CSF) may worsen these conditions, which is the basis for this precaution.
To be medically cleared for donation, the donor must have a negative urine protein test, or the ACR is <5 mg/mmol ensuring that kidney disease is unlikely. If proteinuria is present, the algorithm on the following link must be followed:
https://www.med-guidelines.org.uk/images/c/ca/Urine_algorithm.jpg
For haematuria, please see haematuria
If both blood and protein are present in the urine, both urine ACR and a MC&S/ MSU must be tested.
Pseudonyms or Related Conditions
IgA Nephropathy
Berger’s disease
Glomerulonephritis
Version 1, Edition 1
Date of Last Update
14/07/2025
