Difference between revisions of "Proteinuria"
| (8 intermediate revisions by the same user not shown) | |||
| Line 14: | Line 14: | ||
==Guidance== | ==Guidance== | ||
| − | If | + | |
| − | + | If isolated proteinuria is detected, a urine albumin-to-creatinine ratio (ACR) test must be conducted. Proteinuria can be a sign of underlying kidney conditions such as IgA nephropathy or glomerulonephritis, both of which are often undiagnosed. Administration of granulocyte colony-stimulating factor (G-CSF) may worsen these conditions, which is the basis for this precaution. | |
| + | |||
| + | To be medically cleared for donation, the donor must have a negative urine protein test, or the ACR is <5 mg/mmol ensuring that kidney disease is unlikely. If proteinuria is present, the algorithm on the following link must be followed: | ||
| + | |||
| + | https://www.med-guidelines.org.uk/images/c/ca/Urine_algorithm.jpg | ||
For haematuria, please see [[haematuria]] | For haematuria, please see [[haematuria]] | ||
| + | |||
| + | If both blood and protein are present in the urine, both urine ACR and a MC&S/ MSU must be tested. | ||
==Pseudonyms or Related Conditions== | ==Pseudonyms or Related Conditions== | ||
Latest revision as of 12:15, 16 July 2025
Contents
Acceptability at Recruitment
ACCEPTABLE
Acceptability at VT / Work-Up
ACCEPTABLE
Individual at risk
Donor
Explanation of Condition
Protein present in urine, found either from a urine dipstick test or a Microbiology, Culture & Sensitive (MC&S) test.
Guidance
If isolated proteinuria is detected, a urine albumin-to-creatinine ratio (ACR) test must be conducted. Proteinuria can be a sign of underlying kidney conditions such as IgA nephropathy or glomerulonephritis, both of which are often undiagnosed. Administration of granulocyte colony-stimulating factor (G-CSF) may worsen these conditions, which is the basis for this precaution.
To be medically cleared for donation, the donor must have a negative urine protein test, or the ACR is <5 mg/mmol ensuring that kidney disease is unlikely. If proteinuria is present, the algorithm on the following link must be followed:
https://www.med-guidelines.org.uk/images/c/ca/Urine_algorithm.jpg
For haematuria, please see haematuria
If both blood and protein are present in the urine, both urine ACR and a MC&S/ MSU must be tested.
Pseudonyms or Related Conditions
IgA Nephropathy
Berger’s disease
Glomerulonephritis
Version 1, Edition 1
Date of Last Update
14/07/2025
