Difference between revisions of "Proteinuria"

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If protein is detected in the urine, a urine albumin-to-creatinine ratio (ACR) test must be conducted. Proteinuria can be a sign of underlying kidney conditions such as IgA nephropathy or glomerulonephritis, both of which are often undiagnosed. Administration of granulocyte colony-stimulating factor (G-CSF) may worsen these conditions, which is the basis for this precaution.
 
If protein is detected in the urine, a urine albumin-to-creatinine ratio (ACR) test must be conducted. Proteinuria can be a sign of underlying kidney conditions such as IgA nephropathy or glomerulonephritis, both of which are often undiagnosed. Administration of granulocyte colony-stimulating factor (G-CSF) may worsen these conditions, which is the basis for this precaution.
  
To be medically cleared for donation, the donor must have a negative urine protein test, ensuring that these kidney diseases are unlikely. If proteinuria is present, the following clinical algorithm must be followed:
+
To be medically cleared for donation, the donor must have a negative urine protein test, ensuring that these kidney diseases are unlikely. If proteinuria is present, the algorithm on the following link must be followed:
 +
 
 +
https://www.med-guidelines.org.uk/index.php?title=File:Urine_algorithm&action=edit&redlink=1
  
[[File:Urine algorithm|thumb]]
 
  
 
For haematuria, please see [[haematuria]]
 
For haematuria, please see [[haematuria]]

Revision as of 09:59, 15 July 2025


Acceptability at Recruitment

ACCEPTABLE

Acceptability at VT / Work-Up

ACCEPTABLE

Individual at risk

Donor

Explanation of Condition

Protein present in urine, found either from a urine dipstick test or a Microbiology, Culture & Sensitive (MC&S) test.

Guidance

If protein is detected in the urine, a urine albumin-to-creatinine ratio (ACR) test must be conducted. Proteinuria can be a sign of underlying kidney conditions such as IgA nephropathy or glomerulonephritis, both of which are often undiagnosed. Administration of granulocyte colony-stimulating factor (G-CSF) may worsen these conditions, which is the basis for this precaution.

To be medically cleared for donation, the donor must have a negative urine protein test, ensuring that these kidney diseases are unlikely. If proteinuria is present, the algorithm on the following link must be followed:

https://www.med-guidelines.org.uk/index.php?title=File:Urine_algorithm&action=edit&redlink=1


For haematuria, please see haematuria

Pseudonyms or Related Conditions

IgA Nephropathy

Berger’s disease

Glomerulonephritis

Version 1, Edition 1

Date of Last Update

14/07/2025