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=About the Anthony Nolan Medical and Lifestyle Guidelines=
 
=About the Anthony Nolan Medical and Lifestyle Guidelines=
  
−
Please note that this guide is primarily intended as a reference tool for Anthony Nolan
+
For potential and current donors, please note that these guidelines are primarily intended for use by Anthony Nolan staff.
−
staff and affiliated Anthon Nolan Recruitment Groups. It is not a guide intended for direct
+
 
−
distribution to the general public, although it is available for public viewing if required.  
+
The Anthony Nolan Medical and Lifestyle Guidelines are put in place to ensure the safety of both our stem cell donors and the recipients of their donations.
 +
 
 +
Because of the volunteer nature of stem cell donation, we have a responsibility to ensure that our donors are able to donate safely, with minimal risk to their own health. For this reason, our medical criteria are  strict, and considerably more strict than medical criteria for having a procedure, such as an operation, for the benefit of your own health.
 +
 
 +
Some donor medical conditions present a risk to the '''recipient''' of the donation. In these cases, we may allow a donor to donate because the benefit for the patient of receiving the transplant outweighs the risk.  
 +
 
 +
=Guidance for Recruiters=
  
 
The list is not exhaustive; therefore, particular cases may require further clarification by our Medical Officer.
 
The list is not exhaustive; therefore, particular cases may require further clarification by our Medical Officer.
Line 37: Line 43:
  
 
=Recently Updated Guidance=
 
=Recently Updated Guidance=
−
'''20/6/12. Guidance Added:''' [[Essential Tremor]]
 
−
 
−
'''21/6/12. Guidance Added:''' Bronchitis, See [[Infection, Acute]]
 
−
 
−
'''22/6/12. Guidance Added:''' [[POTS (Postural Orthostatic Tachycardia Syndrome)]]
 
−
 
−
'''26/6/12. Guidance Updated:''' [[Surgery]]
 
−
 
−
'''28/6/12. Guidance Added:''' Blood Clot, See [[Thrombosis]]
 
−
 
−
'''11/7/12. Guidance Added:''' [[Cluster Headache]]
 
−
 
−
'''18/7/12. Guidance Added:''' [[Haemangioma]]
 
  
−
'''18/7/12. Guidance Updated:''' [[Alopecia]]
 
  
−
'''8/8/12. Guidance Updated:''' [[Non Steroidal Anti-Inflammatory Drug]]
+
Review of all guidelines June 2016
  
 
=Multiple Medical Conditions=
 
=Multiple Medical Conditions=
Line 62: Line 54:
  
 
If in doubt, please discuss these donors with the medical officer.
 
If in doubt, please discuss these donors with the medical officer.
 +
 +
=Post donation guidelines=
 +
[[Post-donation guidelines]]
  
 
=Index of Conditions=
 
=Index of Conditions=
Line 68: Line 63:
  
 
Accident, See [[Fracture]] and/or [[Surgery]]
 
Accident, See [[Fracture]] and/or [[Surgery]]
 +
 +
Abnormal LFTs, See [[Liver Function, Abnormal]]
  
 
[[Acetylcholinesterase Deficiency]]
 
[[Acetylcholinesterase Deficiency]]
Line 88: Line 85:
  
 
ADD, See [[Attention Deficit Hyperactivity Disorder]]
 
ADD, See [[Attention Deficit Hyperactivity Disorder]]
−
 
−
[[Addiction and Drug Abuse]]
 
  
 
[[Addison Disease]]
 
[[Addison Disease]]
Line 115: Line 110:
 
[[Alpha 1 Antitrypsin Deficiency]]
 
[[Alpha 1 Antitrypsin Deficiency]]
  
−
[[Alpha Mannosidosis]]  
+
Alpha Mannosidosis, See [[Inherited Disease]]
  
 
[[Alports Syndrome]]
 
[[Alports Syndrome]]
Line 132: Line 127:
  
 
Anthrax Vaccine, See [[Immunisation]]
 
Anthrax Vaccine, See [[Immunisation]]
 +
 +
[[Anti-doping guidance]]
  
 
Anti-Inflammatory Drug, See [[Non Steroidal Anti-Inflammatory Drug]]
 
Anti-Inflammatory Drug, See [[Non Steroidal Anti-Inflammatory Drug]]
Line 154: Line 151:
  
 
Aortic Valve Disease, See [[Heart, Valve Disease]]
 
Aortic Valve Disease, See [[Heart, Valve Disease]]
 +
 +
[[Arachnoid Cyst]]
  
 
[[Arnold-Chiari Syndrome]]  
 
[[Arnold-Chiari Syndrome]]  
Line 170: Line 169:
  
 
Atherosclerosis, See [[Heart, Coronary Artery Disease]]
 
Atherosclerosis, See [[Heart, Coronary Artery Disease]]
 +
 +
Athlete, See [[Anti-doping guidance]]
  
 
Atrial Fibrillation, See [[Heart, Arrhythmia]]  
 
Atrial Fibrillation, See [[Heart, Arrhythmia]]  
Line 248: Line 249:
  
 
BPH, See [[Benign Prostatic Hyperplasia]]
 
BPH, See [[Benign Prostatic Hyperplasia]]
 +
 +
[[BRAIN BLEED]]
 +
 +
[[Brain Injury]]
  
 
Brain Surgery, See [[Neurosurgery]]
 
Brain Surgery, See [[Neurosurgery]]
  
 
[[Brain Tumour]]
 
[[Brain Tumour]]
 +
 +
BRCA Mutation, See [[Pre-Malignant Conditions]]
  
 
[[Breast Augmentation (Implants)]]  
 
[[Breast Augmentation (Implants)]]  
 +
 +
[[Breast Feeding]]
  
 
[[Bronchiectasis]]  
 
[[Bronchiectasis]]  
Line 301: Line 310:
 
[[Cerebroretinal Angiomatosis]]
 
[[Cerebroretinal Angiomatosis]]
  
−
Cerebrovascular Accident, See [[Stroke]]
+
[[Cerebrovascular Disease]]
  
 
[[Cervical Carcinoma In-Situ]]
 
[[Cervical Carcinoma In-Situ]]
  
−
Cervical Smear, See [[Cervical Carcinoma In-Situ]]
+
Cervical Intraepithelial Neoplasia (CIN), See [[Pre-Malignant Conditions]]
  
 
Cervical Spondylosis, See [[Back Conditions]]
 
Cervical Spondylosis, See [[Back Conditions]]
Line 314: Line 323:
  
 
[[Chicken Pox]]  
 
[[Chicken Pox]]  
 +
 +
Chikungunya, See[[Tropical Viruses]]
  
 
Chlamydia, See [[Infection, Acute]]
 
Chlamydia, See [[Infection, Acute]]
Line 340: Line 351:
  
 
Coagulation Disorder, See [[Bleeding Disorder]] or [[Thrombophilia]]
 
Coagulation Disorder, See [[Bleeding Disorder]] or [[Thrombophilia]]
 +
 +
Coarctation of the aorta, See [[Heart, Congenital Defect]]
  
 
Coccydynia, See [[Back Conditions]]  
 
Coccydynia, See [[Back Conditions]]  
  
 
[[Coeliac Disease]]
 
[[Coeliac Disease]]
−
 
−
[[Cold]]
 
  
 
Coldsore, See [[Herpes Simplex Virus]]
 
Coldsore, See [[Herpes Simplex Virus]]
  
−
[[Colitis]]  
+
[[Colitis]]
  
 
Cone Biopsy, See [[Cervical Carcinoma In-Situ]]
 
Cone Biopsy, See [[Cervical Carcinoma In-Situ]]
Line 372: Line 383:
  
 
Coronary Thrombosis, See [[Heart, Coronary Artery Disease]]
 
Coronary Thrombosis, See [[Heart, Coronary Artery Disease]]
 +
 +
[[Coronavirus]]
 +
 +
[[Costochondritis]]
  
 
[[Cow Pox]]  
 
[[Cow Pox]]  
Line 394: Line 409:
  
 
[[Cystic Fibrosis]]  
 
[[Cystic Fibrosis]]  
−
 
−
[[Cystic Fibrosis Carrier]]
 
  
 
[[Cystinuria]]  
 
[[Cystinuria]]  
Line 409: Line 422:
 
Deep Vein Thrombosis, See [[Thrombosis]]
 
Deep Vein Thrombosis, See [[Thrombosis]]
  
−
Dengue Fever, See [[Infection, Acute]]  
+
Dengue Fever, See [[Tropical Viruses]]  
  
 
[[Depression]]  
 
[[Depression]]  
Line 425: Line 438:
 
[[Diabetes Mellitus]]
 
[[Diabetes Mellitus]]
  
−
Diamond-Blackfan Syndrome, See [[Inherited Disease]]
+
Diamond-Blackfan Syndrome, see [[Inherited Disease]]
  
 
Diclofenac, See [[Non Steroidal Anti-Inflammatory Drug]]
 
Diclofenac, See [[Non Steroidal Anti-Inflammatory Drug]]
Line 443: Line 456:
 
[[Down Syndrome]]  
 
[[Down Syndrome]]  
  
−
Drug Abuse, See [[Addiction and Drug Abuse]]
+
Drug Abuse, See [[Injection of Non-Prescription drugs]]
  
 
Drug Treatment, See [[Medications]]  
 
Drug Treatment, See [[Medications]]  
Line 469: Line 482:
 
==E==
 
==E==
  
−
[[Ebola Fever]]
+
Ebola Fever,See [[Viral Haemorrhagic Fever]]
  
 
EBV, See [[Epstein-Barr Virus]]
 
EBV, See [[Epstein-Barr Virus]]
Line 529: Line 542:
 
Familial Hypercholesterolaemia, See [[Hyperlipidaemia]]
 
Familial Hypercholesterolaemia, See [[Hyperlipidaemia]]
  
−
[[Familial Mediterranean Fever]]  
+
[[Familial Mediterranean Fever]]
  
−
[[Familial Polyposis]]  
+
Familial Adenomatous Polyposis, See [[Pre-Malignant Conditions]]  
  
 
[[Fat Embolism]]  
 
[[Fat Embolism]]  
Line 583: Line 596:
 
[[Gaucher Disease]]  
 
[[Gaucher Disease]]  
  
−
[[Gender Reassignment]]
+
Gender Reassignment See [[Transgender]]
  
 
Genetic Traits, See [[Inherited Disease]]
 
Genetic Traits, See [[Inherited Disease]]
Line 610: Line 623:
  
 
[[Gonorrhoea]]
 
[[Gonorrhoea]]
 +
 +
[[Gout]]
  
 
[[Granuloma Annulare]]  
 
[[Granuloma Annulare]]  
Line 712: Line 727:
  
 
High Affinity Haemoglobin, See [[Haemoglobin Disorder]]
 
High Affinity Haemoglobin, See [[Haemoglobin Disorder]]
 +
 +
[[High bilirubin]]
  
 
High Cholesterol, See [[Hyperlipidaemia]]
 
High Cholesterol, See [[Hyperlipidaemia]]
 +
 +
[[High ferritin]]
  
 
[[High Risk Sexual Behaviour]]
 
[[High Risk Sexual Behaviour]]
Line 752: Line 771:
  
 
[[Hyperaldosteronism]]
 
[[Hyperaldosteronism]]
 +
 +
Hyperbilirubinaemia, see [[High bilirubin]]
  
 
Hypercholesterolaemia, See [[Hyperlipidaemia]]
 
Hypercholesterolaemia, See [[Hyperlipidaemia]]
 +
 +
Hyperferritinaemia, See [[High ferritin]]
  
 
[[Hyperlipidaemia]]  
 
[[Hyperlipidaemia]]  
Line 788: Line 811:
  
 
Ibuprofen, See [[Non Steroidal Anti-Inflammatory Drug]]
 
Ibuprofen, See [[Non Steroidal Anti-Inflammatory Drug]]
−
 
−
[[Idiopathic Hypersomnia]]
 
  
 
[[Idiopathic Intracranial Hypertension]]  
 
[[Idiopathic Intracranial Hypertension]]  
Line 826: Line 847:
  
 
Influenza Vaccination, See [[Immunisation]]
 
Influenza Vaccination, See [[Immunisation]]
 +
 +
[[Inherited Blood Disorder, first degree relative with]]
 +
 +
[[Injection of Non-Prescription drugs]]
  
 
[[Inherited Disease]]
 
[[Inherited Disease]]
Line 835: Line 860:
 
[[Iron Deficiency (Anaemia)]]
 
[[Iron Deficiency (Anaemia)]]
  
−
[[Irritable Bowel Disease]]  
+
[[Irritable Bowel Syndrome]]  
  
 
Ischaemic Heart Disease, See [[Heart, Coronary Artery Disease]]
 
Ischaemic Heart Disease, See [[Heart, Coronary Artery Disease]]
Line 844: Line 869:
  
 
[[Jaundice]]
 
[[Jaundice]]
−
 
−
Juvenile Chronic Arthritis, See [[Juvenile Idiopathic Arthritis]]
 
  
 
[[Juvenile Idiopathic Arthritis]]
 
[[Juvenile Idiopathic Arthritis]]
−
 
−
Juvenile Rheumatoid Arthritis, See [[Juvenile Idiopathic Arthritis]]
 
  
 
==K==
 
==K==
Line 883: Line 904:
 
[[Laser Treatment]]
 
[[Laser Treatment]]
  
−
[[Lassa Fever]]
+
Lassa Fever, See [[Viral Haemorrhagic Fever]]
  
 
Latex Allergy, See [[Allergy]]
 
Latex Allergy, See [[Allergy]]
Line 889: Line 910:
 
Left Branch Bundle Block, See [[Heart, Arrhythmia]]
 
Left Branch Bundle Block, See [[Heart, Arrhythmia]]
  
−
[[Legionnaire's Disease]]  
+
Legionnaire's Disease, See [[Infection, Acute]]
  
 
[[Leishmaniasis]]
 
[[Leishmaniasis]]
  
−
[[Leptospirosis]]  
+
Leptospirosis See [[Infection, Acute]]
  
 
Leukaemia, See [[Malignancy]]
 
Leukaemia, See [[Malignancy]]
Line 902: Line 923:
  
 
[[Lipoma]]  
 
[[Lipoma]]  
 +
 +
[[Liver Function, Abnormal]]
  
 
Low Blood Pressure, See [[Hypotension]]
 
Low Blood Pressure, See [[Hypotension]]
 +
 +
Low Ferritin, See [[Iron Deficiency (Anaemia)]]
  
 
Low Haemoglobin, See [[Anaemia]]
 
Low Haemoglobin, See [[Anaemia]]
Line 915: Line 940:
 
[[Lupus Anticoagulant]]  
 
[[Lupus Anticoagulant]]  
  
−
[[Lyme Disease]]
+
Lyme Disease, See [[Infection, Acute]]
  
 
[[Lymphadenopathy]]
 
[[Lymphadenopathy]]
Line 937: Line 962:
 
Manic Depression, See [[Bipolar Affective Disorder]]
 
Manic Depression, See [[Bipolar Affective Disorder]]
  
−
[[Marburg Fever]]
+
Marburg Fever, See [[Viral Haemorrhagic Fever]]
  
 
[[Marfan Syndrome]]  
 
[[Marfan Syndrome]]  
  
 
Mastectomy, See [[Surgery]]
 
Mastectomy, See [[Surgery]]
−
 
−
[[Mastitis]]
 
  
 
Mastoid Operation, See [[Surgery]]
 
Mastoid Operation, See [[Surgery]]
Line 950: Line 973:
  
 
Medical Trial, See [[Clinical Trial]]
 
Medical Trial, See [[Clinical Trial]]
−
 
−
[[Medications]]
 
−
 
−
[[Megaloblastic Anaemia]]
 
  
 
Membranous Glomerulonephritis, See [[Kidney Disease]]
 
Membranous Glomerulonephritis, See [[Kidney Disease]]
Line 961: Line 980:
 
Meningioma, See [[Brain Tumour]]
 
Meningioma, See [[Brain Tumour]]
  
−
[[Meningitis]]
+
Meningitis, See [[Infection, Acute]]
−
 
 
−
Meningoencephalitis, See [[Meningitis]]
 
  
 
[[Menopause]]
 
[[Menopause]]
Line 985: Line 1,002:
 
Mitral Valve Disease, See [[Heart, Valve Disease]]
 
Mitral Valve Disease, See [[Heart, Valve Disease]]
  
−
[[Monoclonal Gammopathy]]  
+
Monkeypox, See [[Mpox]]
  
−
[[Mononeuritis]]  
+
[[Monoclonal Gammopathy]]
  
 
Mononucleosis, See [[Epstein-Barr Virus]]  
 
Mononucleosis, See [[Epstein-Barr Virus]]  
Line 996: Line 1,013:
  
 
Motor Sensory Neuropathy, See [[Hereditary Motor Sensory Neuropathy]]  
 
Motor Sensory Neuropathy, See [[Hereditary Motor Sensory Neuropathy]]  
 +
 +
[[Mpox]]
  
 
[[MRSA]]  
 
[[MRSA]]  
Line 1,074: Line 1,093:
  
 
[[Obstructive Sleep Apnoea]]  
 
[[Obstructive Sleep Apnoea]]  
−
 
−
[[Ocular Surgery]]
 
  
 
[[Ocular Tissue Recipient]]
 
[[Ocular Tissue Recipient]]
Line 1,086: Line 1,103:
  
 
[[Optic Neuritis]]  
 
[[Optic Neuritis]]  
−
 
−
[[Osgood Schlatter Disease]]
 
  
 
Osler-Weber-Rendu Disease, See [[Hereditary Haemorrhagic Telangiectasia]]
 
Osler-Weber-Rendu Disease, See [[Hereditary Haemorrhagic Telangiectasia]]
Line 1,120: Line 1,135:
  
 
Paget Disease Of The Nipple, See [[Malignancy]]
 
Paget Disease Of The Nipple, See [[Malignancy]]
 +
 +
[[Pain Medications]]
  
 
[[Palindromic Rheumatism]]  
 
[[Palindromic Rheumatism]]  
Line 1,154: Line 1,171:
  
 
[[Peripheral Vascular Disease]]
 
[[Peripheral Vascular Disease]]
−
 
−
[[Peritonitis]]
 
  
 
[[Pernicious Anaemia]]  
 
[[Pernicious Anaemia]]  
Line 1,181: Line 1,196:
 
[[Pleurisy]]  
 
[[Pleurisy]]  
  
−
[[Pneumonia]]  
+
Pneumonia, See [[Infection, Acute]]
  
 
[[Pneumothorax]]  
 
[[Pneumothorax]]  
Line 1,188: Line 1,203:
  
 
Polyarteritis Nodosa, See [[Vasculitis]]
 
Polyarteritis Nodosa, See [[Vasculitis]]
−
 
−
[[Polycystic Kidney Disease]]
 
  
 
[[Polycystic Ovarian Syndrome]]
 
[[Polycystic Ovarian Syndrome]]
Line 1,202: Line 1,215:
  
 
Positive Cervical Smear, See [[Cervical Carcinoma In-Situ]]
 
Positive Cervical Smear, See [[Cervical Carcinoma In-Situ]]
 +
 +
[[Post-donation guidelines]]
  
 
Post-Viral Fatigue Syndrome, See [[Myalgic Encephalomyelitis]]
 
Post-Viral Fatigue Syndrome, See [[Myalgic Encephalomyelitis]]
  
−
[[POTS (Postural Orthostatic Tachycardia Syndrome)]]
+
[[POTS (Postural Orthostatic Tachycardia Syndrome)]]  
−
 
 
−
[[Pre-Cancerous Cells]]  
 
  
 
[[Pre-Eclampsia]]
 
[[Pre-Eclampsia]]
  
 
[[Pregnancy]]  
 
[[Pregnancy]]  
 +
 +
[[Pre-Malignant Conditions]]
 +
 +
[[PrEP]]
  
 
[[Prion-Associated Disease]]
 
[[Prion-Associated Disease]]
Line 1,217: Line 1,234:
 
[[Proctitis]]  
 
[[Proctitis]]  
  
−
[[Prolactinoma]]  
+
Prolactinoma, See [[Pituitary Adenoma]]
  
 
Prolapsed Disc, See [[Back Conditions]]
 
Prolapsed Disc, See [[Back Conditions]]
Line 1,230: Line 1,247:
  
 
Prothrombin Gene Mutation, See [[Thrombophilia]]
 
Prothrombin Gene Mutation, See [[Thrombophilia]]
 +
 +
Psychosis, see [[Schizophrenia]]
  
 
[[Psoriasis]]  
 
[[Psoriasis]]  
Line 1,320: Line 1,339:
  
 
[[Schistosomiasis]]  
 
[[Schistosomiasis]]  
 +
 +
[[Schizophrenia]]
  
 
Schwannoma, See [[Acoustic Neuroma]]
 
Schwannoma, See [[Acoustic Neuroma]]
Line 1,340: Line 1,361:
  
 
[[Sexual Orientation]]
 
[[Sexual Orientation]]
−
 
−
[[Sexually Transmitted Diseases]]
 
  
 
Shingles, See [[Chicken Pox]]
 
Shingles, See [[Chicken Pox]]
Line 1,378: Line 1,397:
  
 
[[Splenectomy]]
 
[[Splenectomy]]
 +
 +
[[Splenomegaly]]
  
 
Spondylolisthesis, See [[Back Conditions]]
 
Spondylolisthesis, See [[Back Conditions]]
Line 1,395: Line 1,416:
 
[[Still Disease]]
 
[[Still Disease]]
  
−
[[Stroke]]
+
Stroke, See [[Cerebrovascular Disease]]
  
 
[[Subarachnoid Haemorrhage]]  
 
[[Subarachnoid Haemorrhage]]  
Line 1,473: Line 1,494:
 
[[Transfusion]]
 
[[Transfusion]]
  
−
Transient Ischaemic Attack (TIA), See [[Stroke]]
+
Transient Ischaemic Attack (TIA), See [[Cerebrovascular Disease]]
  
−
[[Transsexual]]  
+
[[Transgender]]  
  
 
Treacher-Collins Syndrome, See [[Inherited Disease]]
 
Treacher-Collins Syndrome, See [[Inherited Disease]]
Line 1,484: Line 1,505:
  
 
Tricuspid Stenosis, See [[Heart, Valve Disease]]  
 
Tricuspid Stenosis, See [[Heart, Valve Disease]]  
 +
 +
[[Tropical Viruses]]
 +
 +
[[Tropical viruses ALERTS]]
  
 
[[Trigeminal Neuralgia]]  
 
[[Trigeminal Neuralgia]]  
Line 1,524: Line 1,549:
  
 
Vestibular Schwannoma, See [[Acoustic Neuroma]]
 
Vestibular Schwannoma, See [[Acoustic Neuroma]]
 +
 +
[[Viral Haemorrhagic Fever]]
  
 
Visceral Leishmaniasis, See [[Leishmaniasis]]
 
Visceral Leishmaniasis, See [[Leishmaniasis]]
Line 1,540: Line 1,567:
  
 
[[Weight]]  
 
[[Weight]]  
 +
 +
[[Weight loss medications]]
  
 
Weil Disease, See [[Leptospirosis]]
 
Weil Disease, See [[Leptospirosis]]
Line 1,562: Line 1,591:
  
 
==Z==
 
==Z==
 +
Zika Virus, See [[Tropical Viruses]]
 +
 +
=Appendix 1 - Haematologic and biochemical testing at donor medical=
 +
 +
'''The following haematological and biochemical tests are performed at the donor medical:'''
  
−
=Appendix 1 - Haematologic and biochemical parameters at donor medical=
+
Full blood count
 +
 
 +
Urea and Electrolytes
 +
 
 +
Liver function tests
 +
 
 +
Bone function tests
 +
 
 +
Cholesterol
 +
 
 +
Random glucose
 +
 
 +
Coagulation screen (PT, APTT and fibrinogen)
 +
 
 +
ABO and Rh blood grouping
 +
 
 +
Pregnancy test (B-HCG), if relevant
  
 
=Appendix 2 - Infectious disease marker testing at ET/CT and donor medical=
 
=Appendix 2 - Infectious disease marker testing at ET/CT and donor medical=
 +
 +
'''The following infectious disease markers are tested for all donors at the donor medical:'''
 +
 +
HIV (P24 antigen and antibody)
 +
 +
Hepatitis B (surface antigen and core antibody)
 +
 +
Hepatitis C (antibody and RNA)
 +
 +
HTLV I+II (antibody)
 +
 +
Syphilis (antibody)
 +
 +
Toxoplama (antibody)
 +
 +
EBV (VCA/NA IgG)
 +
 +
CMV (IgG)
 +
 +
Varicella (IgG)
 +
 +
 +
'''The following infectious disease markers may be tested if a relevant travel history is given by the donor, at the discretion of the harvest physician or Anthony Nolan medical officer:'''
 +
 +
Malarial antigen/antibodies
 +
 +
T.cruzi (Chagas disease) antibodies
 +
 +
West nile virus NAT
  
 
=Appendix 3 - Other investigations at donor medical=
 
=Appendix 3 - Other investigations at donor medical=
 +
 +
 +
Electrocardiogram (ECG)
 +
 +
Chest X-ray
  
 
=Appendix 4 - Special consideration for donors in the Armed Forces=
 
=Appendix 4 - Special consideration for donors in the Armed Forces=

Latest revision as of 13:57, 18 September 2024

About the Anthony Nolan Medical and Lifestyle Guidelines

For potential and current donors, please note that these guidelines are primarily intended for use by Anthony Nolan staff.

The Anthony Nolan Medical and Lifestyle Guidelines are put in place to ensure the safety of both our stem cell donors and the recipients of their donations.

Because of the volunteer nature of stem cell donation, we have a responsibility to ensure that our donors are able to donate safely, with minimal risk to their own health. For this reason, our medical criteria are strict, and considerably more strict than medical criteria for having a procedure, such as an operation, for the benefit of your own health.

Some donor medical conditions present a risk to the recipient of the donation. In these cases, we may allow a donor to donate because the benefit for the patient of receiving the transplant outweighs the risk.

Guidance for Recruiters

The list is not exhaustive; therefore, particular cases may require further clarification by our Medical Officer.

IN SUCH CASES PLEASE NOTE THE FOLLOWING: The volunteer should be asked to complete an application form giving full details of their medical status ensuring that the following information is given:

  • Name of medical condition.
  • Date of diagnosis.
  • Name of medication(s) taken.
  • Length of time medication has been taken.
  • Is the medication seen as a short course or long-term prescription?
  • Does the volunteer have any limitations to life-style?
  • Is the volunteer’s condition regularly assessed by GP/Consultant?

Once the application has been reviewed the donor will be contacted and informed of the decision.

This list is in place to help us recruit medically eligible volunteer blood stem cell donors. We have a duty to ensure that volunteer donors are put at minimal risk whilst also considering the safety and outcome for transplant recipients.

The criteria, which we use to assess the suitability of a volunteer to donate, are considerably more stringent than those taken into consideration for volunteers undergoing a procedure for their own medical health status.


If you have any queries please contact The Anthony Nolan Donor Support Team as follows:

Telephone 0303 303 0303 (9am – 5pm) and ask for The Donor Support Team or E-mail: info@anthonynolan.org

Recently Updated Guidance

Review of all guidelines June 2016

Multiple Medical Conditions

Some donors will have more than one medical problem, and the potential combinations are too numerous to list in this guidance. Some combinations of conditions will increase the risk of donor harm, despite being acceptable in isolation.

For example, hypertension, smoking, high cholesterol and diet-controlled diabetes may all be acceptable, but this combination in an older donor would considerably increase their risk of a heart attack or stroke.

If in doubt, please discuss these donors with the medical officer.

Post donation guidelines

Post-donation guidelines

Index of Conditions

A

Accident, See Fracture and/or Surgery

Abnormal LFTs, See Liver Function, Abnormal

Acetylcholinesterase Deficiency

Achondroplasia

Acitretin, See Acne

Acne

Acoustic Neuroma

Acoustic Schwannoma, See Acoustic Neuroma

Acromegaly

Actinic Prurigo

Acupuncture

ADD, See Attention Deficit Hyperactivity Disorder

Addison Disease

Adenocarcinoma, See Malignancy

Adenoma

ADHD, See Attention Deficit Hyperactivity Disorder

Adrenal Hyperplasia, See Congenital Adrenal Hyperplasia

African Trypanosomiasis

AIDS, See HIV

Albino

Alcohol Intake

Allergy

Alopecia

Alpha 1 Antitrypsin Deficiency

Alpha Mannosidosis, See Inherited Disease

Alports Syndrome

Anabolic Steroids, See Addiction and Drug Abuse

Anaemia

Anaesthetic Complications

Angina, See Heart, Coronary Artery Disease

Animal Bite

Ankylosing Spondylitis

Anthrax Vaccine, See Immunisation

Anti-doping guidance

Anti-Inflammatory Drug, See Non Steroidal Anti-Inflammatory Drug

Anti-Phospholipid Syndrome

Antibiotic Treatment

Antibodies

Anticoagulants

Anticonvulsants, See Epilepsy

Antithrombin Deficiency, See Thrombophilia

Anxiety Disorder

Aortic Regurgitation, See Heart, Valve Disease

Aortic Stenosis, See Heart, Valve Disease

Aortic Valve Disease, See Heart, Valve Disease

Arachnoid Cyst

Arnold-Chiari Syndrome

Arrhythmia, See Heart, Arrhythmia

Arthrogryposis

Arthroscopy, See Surgery

Asperger Syndrome

Aspirin, See Non Steroidal Anti-Inflammatory Drug

Asthma

Atherosclerosis, See Heart, Coronary Artery Disease

Athlete, See Anti-doping guidance

Atrial Fibrillation, See Heart, Arrhythmia

Atrial Myxoma, See Myxoma

Atrial Septal Defect (ASD), See Heart, Congenital Defect

Attention Deficit Hyperactivity Disorder

Avascular Necrosis

Avodart, See Dutasteride

Avulsion Fracture (Other Than Spinal), See Fracture

Avulsion Fracture (Spinal), See Back Conditions

B

B12 Deficiency

Babesiosis

Back Conditions

Balanitis Xerotica Obliterans (BXO)

Basal Cell Carcinoma

BCG Vaccination, See Immunisation

Bells Palsy

Benign Essential Tremor, See Essential Tremor

Benign Ethnic Neutropenia, See Neutropenia

Benign Intracranial Hypertension, See Idiopathic Intracranial Hypertension

Benign Positional Vertigo

Benign Prostatic Hyperplasia

Berger Disease, See Kidney Disease

Beta Blockers, See Medications

Beta Thalassemia, See Haemoglobin Disorder

Bilateral Scleritis, See Eye Disease

Bilharzia, See Schistosomiasis

Bipolar Affective Disorder

Bisexual, See Sexual Orientation

Bleeding Disorder

Blocked Artery (Heart), See Heart, Coronary Artery Disease

Blood Clot, See Thrombosis

Blood Pressure, See Hypertension

Blood Transfusion, See Transfusion

Body Piercing

Bone Density (Abnormal), See Osteoporosis

Bone Graft, See Surgery and/or Back Conditions

Borreliosis, See Lyme Disease

Bowens Disease, See Malignancy

BPH, See Benign Prostatic Hyperplasia

BRAIN BLEED

Brain Injury

Brain Surgery, See Neurosurgery

Brain Tumour

BRCA Mutation, See Pre-Malignant Conditions

Breast Augmentation (Implants)

Breast Feeding

Bronchiectasis

Bronchitis, See Infection, Acute

Brown-Sequard Syndrome, See Central Nervous System Disease

Brucellosis

Bursitis

C

C1 Esterase Inhibitor Deficiency

Cancer, See Malignancy

Candida Infection

Candidiasis, See Candida Infection

Carcinoid Syndrome, See Malignancy

Cardiac Failure, See Heart, Muscle Disease

Cardiac Syndrome X, See Heart, Coronary Artery Disease

Cardiomegaly, See Heart, Muscle Disease

Cardiomyopathy, See Heart, Muscle Disease

Carpal Tunnel Syndrome

Cat-Scratch Fever, See Infection, Acute

Causalgia

Cellulitis, See Infection, Acute

Central Nervous System Disease

Cerebral Malaria, See Malaria

Cerebral Palsy

Cerebroretinal Angiomatosis

Cerebrovascular Disease

Cervical Carcinoma In-Situ

Cervical Intraepithelial Neoplasia (CIN), See Pre-Malignant Conditions

Cervical Spondylosis, See Back Conditions

Chagas Disease, See South American Trypanosomiasis

Charcot Marie Tooth Syndrome, See Hereditary Motor Sensory Neuropathy

Chicken Pox

Chikungunya, SeeTropical Viruses

Chlamydia, See Infection, Acute

Cholecystectomy, See Surgery

Cholecystitis, See Gall-Bladder Disease

Chondromalacia Patellae

Christmas Disease, See Bleeding Disorder

Chronic Fatigue Syndrome, See Myalgic Encephalomyelitis

Chronic Obstructive Pulmonary Disease

Cirrhosis

CJD, See Prion-Associated Disease

Clap, See Gonorrhoea

Clinical Trial

Cluster Headache

Coagulation Disorder, See Bleeding Disorder or Thrombophilia

Coarctation of the aorta, See Heart, Congenital Defect

Coccydynia, See Back Conditions

Coeliac Disease

Coldsore, See Herpes Simplex Virus

Colitis

Cone Biopsy, See Cervical Carcinoma In-Situ

Congenital Adrenal Hyperplasia

Congenital Dwarfism, See Achondroplasia

Congenital Naevus

Congo Fever

Conn Syndrome, See Hyperaldosteronism

Conversion Disorder

COPD, See Chronic Obstructive Pulmonary Disease

Corneal Transplant

Coronary Artery Disease, See Heart, Coronary Artery Disease

Coronary Thrombosis, See Heart, Coronary Artery Disease

Coronavirus

Costochondritis

Cow Pox

Coxsackie Virus, See Infection, Acute

Creutzfeld-Jacob Disease, See Prion-Associated Disease

Crigler-Najjar Sydrome

Crimean Fever, See Brucellosis

Crimean-Congo Haemorrhagic Fever, See Congo Fever

Crohns Disease, See Inflammatory Bowel Disease

Crush Fracture (Spinal), See Back Conditions

Cushing Syndrome/Disease

Cutaneous Leishmaniasis, See Leishmaniasis

Cystic Fibrosis

Cystinuria

Cysts

Cytomegalovirus

D

Darier Disease

Deep Vein Thrombosis, See Thrombosis

Dengue Fever, See Tropical Viruses

Depression

Dermatitis

Dermatitis Herpetiformis

Dermatomyositis

Dextrocardia

Diabetes Insipidus

Diabetes Mellitus

Diamond-Blackfan Syndrome, see Inherited Disease

Diclofenac, See Non Steroidal Anti-Inflammatory Drug

Disabled Volunteer

Disc (Removal/Micro Discectomy), See Back Conditions

Disc Protrusion/Prolapse, See Back Conditions

Discoid Lupus, See Systemic Lupus Erythematosus

Diverticulitis

Double-Jointed, See Hypermobility Syndrome

Down Syndrome

Drug Abuse, See Injection of Non-Prescription drugs

Drug Treatment, See Medications

Drug Trial, See Clinical Trial

Duodenal Ulcer

Duplex Kidney

Dutasteride

Dwarfism, See Achondroplasia

Dysentery, See Infection, Acute

Dysfibrinogenaemia, See Bleeding Disorder

Dyspepsia, See Gastro-Oesophageal Reflux

Diastasis Symphysis Pubis

Dystonia, See Central Nervous System Disease

E

Ebola Fever,See Viral Haemorrhagic Fever

EBV, See Epstein-Barr Virus

Eclampsia, See Pre-Eclampsia

Eczema

Ehlers-Danlos Syndrome

Electrolysis

Elephantiasis, See Filariasis

Emphysema, See Chronic Obstructive Pulmonary Disease

Encephalitis

Endocarditis

Endometriosis

Epidermolysis Bullosa

Epilepsy

Episcleritis, See Eye Disease

Epistaxis

Epstein-Barr Virus

ERPC (Evacuation Of Retained Products Of Conception), See Surgery

Erysipelas

Erythema Multiforme

Erythema Nodosum

Erythromelalgia

Essential Thrombocythemia, See Myeloproliferative Neoplasm

Essential Tremor

Eye Disease

F

Factor 12 (XII) Deficiency

Factor 5 Leiden, See Thrombophilia

Factor 5 (V), 7 (VII), 8 (VIII), 9 (IX), 11 (XI) Deficiency, See Bleeding Disorder

Factor V Leiden, See Thrombophilia

Familial Hypercholesterolaemia, See Hyperlipidaemia

Familial Mediterranean Fever

Familial Adenomatous Polyposis, See Pre-Malignant Conditions

Fat Embolism

Felty Syndrome, See Rheumatoid Arthritis

Fertility Treatment, See Hormone Replacement Therapy

Fibroids

Fibromyalgia

Fibrosarcoma, See Malignancy

Fibrosing Alveolitis

Filariasis

Finasteride

Flu, See Influenza

Folate Deficiency

Fracture

Fragile X Syndrome

G

G6PD Deficiency

Galactosaemia

Gall-Bladder Disease

Gallstones, See Gall-Bladder Disease

Gammopathy, See Malignancy

Ganglion

Gastrectomy

Gastric Ulcer

Gastritis

Gastro-Oesophageal Reflux

Gaucher Disease

Gender Reassignment See Transgender

Genetic Traits, See Inherited Disease

Genital Herpes, See Herpes Simplex Virus

Genital Warts

Giant Cell Tumour

Giardiasis

Gilbert Syndrome

Gilles De La Tourette Syndrome

Glandular Fever, See Epstein-Barr Virus

Glaucoma, See Eye Disease

Glomerulonephritis

Gluten Intolerance, See Coeliac Disease

Goitre (Enlarged Thyroid), See Thyroid Disease

Gonorrhoea

Gout

Granuloma Annulare

Graves Disease, See Thyroid Disease

Growth Hormone Therapy, See Hormone Replacement Therapy

Guillain-Barre Syndrome

Guttate Psoriasis, See Psoriasis

H

H. Pylori, See Helicobacter Pylori

Haemangioma

Haematemesis

Haematuria

Haemochromatosis

Haemoglobin C, See Haemoglobin Disorder

Haemoglobin Camden, See Haemoglobin Disorder

Haemoglobin D, See Haemoglobin Disorder

Haemoglobin Disorder

Haemoglobin E, See Haemoglobin Disorder

Haemoglobin Level, See Anaemia

Haemoglobin S, , See Haemoglobin Disorder

Haemolytic Anaemia

Haemolytic Uraemic Syndrome

Haemophilia, See Bleeding Disorder

Haemophilia Carrier, See Bleeding Disorder

Hand Foot And Mouth

Hashimotos Thyroiditis, See Thyroid Disease

Heart Attack, See Heart, Coronary Artery Disease

Heart Block, See Heart, Arrhythmia

Heart Murmur, See Heart, Valve Disease

Heart, Arrhythmia

Heart, Congenital Defect

Heart, Coronary Artery Disease

Heart, Muscle Disease

Heart, Valve Disease

Heavy Periods, See Menorrhagia

Helicobacter Pylori

HELLP Syndrome

Henoch-Schonlein Purpura, See Vasculitis

Hepatitis A

Hepatitis B

Hepatitis C

Hepatitis E

Hepatitis Of Unknown Origin

Hereditary Elliptocytosis

Hereditary Haemorrhagic Telangiectasia

Hereditary Motor Sensory Neuropathy

Hereditary Polyposis, See Familial Polyposis

Hereditary Spastic Paraplegia, See Central Nervous System Disease

Hereditary Spherocytosis

Hernia

Herpes Simplex Virus

Herpes Zoster Virus, See Chicken Pox

High Affinity Haemoglobin, See Haemoglobin Disorder

High bilirubin

High Cholesterol, See Hyperlipidaemia

High ferritin

High Risk Sexual Behaviour

Hip Dislocation

Hirschsprung’s Disease

HIV

Hodgkin Lymphoma, See Malignancy

Hormone Replacement Therapy

HRT, See Hormone Replacement Therapy

HTLV Infection

Hughes Syndrome, See Anti-Phospholipid Syndrome

Human Bite, See Innoculation Injury

Human Growth Hormone], See Hormone Replacement Therapy

Human Immunodeficiency Virus, See HIV

Human Papilloma Virus

Huntington Disease

Hydatidiform Mole, See Pregnancy

Hydradentis Suppurativa

Hydrocephalus

Hydronephrosis

Hyperaldosteronism

Hyperbilirubinaemia, see High bilirubin

Hypercholesterolaemia, See Hyperlipidaemia

Hyperferritinaemia, See High ferritin

Hyperlipidaemia

Hypermobility Syndrome

Hyperparathyroidism

Hyperprolactinaemia, See Pituitary Adenoma

Hypertension

Hyperthyroidism, See Thyroid Disease

Hypertrophic Obstructive Cardiomyopathy

Hypoadrenalism, See Addison Disease

Hypofibrinogenaemia, See Bleeding Disorder

Hypogonadism

Hypoparathyroidism

Hypopituiarism

Hypotension

Hypothyroidism, See Thyroid Disease

Hysterectomy, See Surgery

I

Ibuprofen, See Non Steroidal Anti-Inflammatory Drug

Idiopathic Intracranial Hypertension

IgA Deficiency

IgA Nephropathy, See Kidney Disease

Ileostomy

Immune Deficiency, See Immunosuppression

Immune Thrombocytopenia

Immunisation

Immunoglobulin Therapy, See Transfusion

Immunosuppression

Impetigo

In-vitro Fertilisation, Seee Hormone Replacement Therapy

Infection, Acute

Infectious Mononucleosis, See Epstein-Barr Virus

Infective Endocarditis, See Endocarditis

Infertility

Inflammatory Bowel Disease

Influenza

Influenza Vaccination, See Immunisation

Inherited Blood Disorder, first degree relative with

Injection of Non-Prescription drugs

Inherited Disease

Innoculation Injury

Intermittent Claudication, See Peripheral Vascular Disease

Iron Deficiency (Anaemia)

Irritable Bowel Syndrome

Ischaemic Heart Disease, See Heart, Coronary Artery Disease

IVF, See Hormone Replacement Therapy

J

Jaundice

Juvenile Idiopathic Arthritis

K

Kala-Azar, See Leishmaniasis

Kallman Syndrome

Kawasaki Disease

Key-Hole Surgery, See Surgery

Kidney Disease

Kidney Transplant, See Tissue Or Organ Transplant

Kidney, Single

Kienbock Disease, See Avascular Necrosis

Klinefelter Syndrome

Kyphosis, See Back Conditions

L

Labyrinthitis

Laminectomy, See Back Conditions

Laparoscopy, See Surgery

Laser Treatment

Lassa Fever, See Viral Haemorrhagic Fever

Latex Allergy, See Allergy

Left Branch Bundle Block, See Heart, Arrhythmia

Legionnaire's Disease, See Infection, Acute

Leishmaniasis

Leptospirosis See Infection, Acute

Leukaemia, See Malignancy

Lichen Planus

Lichen Sclerosus

Lipoma

Liver Function, Abnormal

Low Blood Pressure, See Hypotension

Low Ferritin, See Iron Deficiency (Anaemia)

Low Haemoglobin, See Anaemia

Low Platelets, See Thrombocytopenia

Lumbar Spine Abnormality, See Back Conditions

Lupus, See Systemic Lupus Erythematosus

Lupus Anticoagulant

Lyme Disease, See Infection, Acute

Lymphadenopathy

Lymphoedema

Lymphogranuloma Venereum

M

Macrocytosis

Malaria

Malignancy

Malignant Hyperpyrexia

Malignant Melanoma, See Malignancy

Manic Depression, See Bipolar Affective Disorder

Marburg Fever, See Viral Haemorrhagic Fever

Marfan Syndrome

Mastectomy, See Surgery

Mastoid Operation, See Surgery

ME, See Myalgic Encephalomyelitis

Medical Trial, See Clinical Trial

Membranous Glomerulonephritis, See Kidney Disease

Meniere Disease

Meningioma, See Brain Tumour

Meningitis, See Infection, Acute

Menopause

Menorrhagia

Metabolic Disease, Seee Inherited Disease

MGUS, See Monoclonal Gammopathy

Micropituitary Adenoma, See Pituitary Adenoma

Migraine

Miscarriage

Mitral Regurgitation, See Heart, Valve Disease

Mitral Stenosis, See Heart, Valve Disease

Mitral Valve Disease, See Heart, Valve Disease

Monkeypox, See Mpox

Monoclonal Gammopathy

Mononucleosis, See Epstein-Barr Virus

Morphoea

Motor Neurone Disease, See Central Nervous System Disease

Motor Sensory Neuropathy, See Hereditary Motor Sensory Neuropathy

Mpox

MRSA

MS, See Multiple Sclerosis

Multiple Sclerosis

Muscular Dystrophy

Muscular Dystrophy Carrier

Myalgic Encephalomyelitis

Myasthenia Gravis

Myelodysplasia

Myelofibrosis, See Myeloproliferative Neoplasm

Myeloproliferative Neoplasm

Myocarditis

Myoclonus, See Central Nervous System Disease

Myositis

Myotonia Congenita, See Muscular Dystrophy

Myotonic Dystrophy, See Muscular Dystrophy

Myxoedema, See Thyroid Disease

Myxoma

N

Narcolepsy

Needle Phobia

Needlestick Injury, See Innoculation Injury

Neotigason, See Acne

Nephrectomy (Kidney Removal), See Kidney, Single

Nephritis, See Kidney Disease

Nephropathy, See Kidney Disease

Nephrotic Syndrome, See Kidney Disease

Neurofibromatosis

Neuroma, See Brain Tumour

Neurosurgery

Neutropenia

Non Steroidal Anti-Inflammatory Drug

Non-Hodgkin Lymphoma, See Malignancy

Nose Bleed, See Epistaxis

NSAID, See Non Steroidal Anti-Inflammatory Drug

O

Obesity, See Weight

Obsessive Compulsive Disorder

Obstetric Cholestasis

Obstructive Sleep Apnoea

Ocular Tissue Recipient

Oesophagitis, See Gastro-Oesophageal Reflux

Onchocerciasis

Operation, See Surgery

Optic Neuritis

Osler-Weber-Rendu Disease, See Hereditary Haemorrhagic Telangiectasia

Osteoarthritis

Osteochondroma

Osteodystrophia Deformans, See Paget Disease

Osteogenesis Imperfecta

Osteoma, See Osteochondroma

Osteomalacia

Osteomyelitis

Osteopenia

Osteoporosis

Otosclerosis

Ovarian Cyst

P

Pacemaker, See Heart, Arrhythmia

Paget Disease

Paget Disease Of The Nipple, See Malignancy

Pain Medications

Palindromic Rheumatism

Pancreatitis

Panic Attacks, See Anxiety Disorder

Paraplegia, See Disabled Volunteer

Paraprotein, See Monoclonal Gammopathy

Paratyphoid Fever

Parkinson Disease, See Central Nervous System Disease

Parvovirus

Patent Ductus Arteriosus, See Heart, Congenital Defect

Patent Foramen Ovale, See Heart, Congenital Defect

Pelvic Inflammatory Disease

Pemphigoid

Pemphigus

Peptic Ulcer

Pericarditis

Peripheral Neuropathy

Peripheral Vascular Disease

Pernicious Anaemia

Peroneal Muscular Atrophy, See Hereditary Motor Sensory Neuropathy

Perthes Disease

Peyronie Disease

Phaeochromocytoma, See Malignancy

Phenylketonuria

Phlebitis

Pilonidal Sinus

Pituitary Adenoma

Pityriasis

Pleural Effusion

Pleurisy

Pneumonia, See Infection, Acute

Pneumothorax

Polio, See Disabled Volunteer

Polyarteritis Nodosa, See Vasculitis

Polycystic Ovarian Syndrome

Polycythaemia

Polycythemia Rubra Vera, See Myeloproliferative Neoplasm

Polymyalgia

Porphyria (All Types)

Positive Cervical Smear, See Cervical Carcinoma In-Situ

Post-donation guidelines

Post-Viral Fatigue Syndrome, See Myalgic Encephalomyelitis

POTS (Postural Orthostatic Tachycardia Syndrome)

Pre-Eclampsia

Pregnancy

Pre-Malignant Conditions

PrEP

Prion-Associated Disease

Proctitis

Prolactinoma, See Pituitary Adenoma

Prolapsed Disc, See Back Conditions

Prostate, Enlarged

Prostatism, See Benign Prostatic Hyperplasia

Protein C Deficiency, See Thrombophilia

Protein S Deficiency, See Thrombophilia

Prothrombin Gene Mutation, See Thrombophilia

Psychosis, see Schizophrenia

Psoriasis

Psoriatic Arthritis, See Psoriasis

Pulmonary Embolus, See Thrombosis

Pulmonary Stenosis / Regurgitation, See Heart, Congenital Defect

Pulmonary Valvotomy, See Heart, Valve Disease

Purpura

Pyelonephritis, See Kidney Disease

Pyloric Stenosis

Pyruvate Kinase Deficiency

Q

Q Fever

R

Rabies

Radionuclide Therapy

Radiotherapy

Raynaud Disease

Reactive Arthritis

Reflex Sympathetic Dystrophy

Reflux, See Gastro-Oesophageal Reflux

Reiter Syndrome, See Reactive Arthritis

Renal Colic, See Kidney Disease

Renal Disease, See Kidney Disease

Restless Legs Syndrome

Retinitis Pigmentosa

Retinoic Acid Derivatives

Reye Syndrome

Rheumatic Fever

Rheumatoid Arthritis

Rhinitis

Ricketts, See Disabled Volunteer

Rickettsial Infection

Right Bundle Branch Block, See Heart, Arrhythmia

Ringworm

River Blindness, See Onchocerciasis

Roaccutane, See Acne

Rocky Mountain Spotted Fever, See Rickettsial Infection

Rodent Ulcer, See Basal Cell Carcinoma

Rosacea

S

Sacroiliac Joint Problems, See Back Conditions

Sandhoff Disease, See Inherited Disease

Sarcoidosis

Scarlet Fever

Scheuermann Disease, See Back Conditions

Schistosomiasis

Schizophrenia

Schwannoma, See Acoustic Neuroma

Sciatica, See Back Conditions

Scleroderma

Scoliosis, See Back Conditions

Sebaceous Cyst

Seborrhoeic Dermatitis

Seizures, See Epilepsy

Septicaemia

Sex Change, See Gender Reassignment

Sexual Orientation

Shingles, See Chicken Pox

Shwachman-Diamond Syndrome, See Inherited Disease

Sickle Cell Disease

Sickle Cell Trait

Simple Cyst

Situs Inversus

Sjogren’s Syndrome

Sleeping Sickness, See African Trypanosomiasis

Smear - Abnormal Cervical, See Cervical Carcinoma In-Situ

South American Trypanosomiasis

Spasmodic Torticollis, See Back Conditions

Spherocytosis, See Hereditary Spherocytosis

Spina Bifida

Spinal Fusion, See Back Conditions

Spinal Muscular Atrophy, See Inherited Disease

Spinal Stenosis, See Back Conditions

Spitz Naevus

Splenectomy

Splenomegaly

Spondylolisthesis, See Back Conditions

Spondylosis, See Back Conditions

Spot Baldness, See Alopecia Areata

Spots, See Acne

Steroid Treatment

Stevens-Johnson Syndrome

Stickler Syndrome, See Inherited Disease

Still Disease

Stroke, See Cerebrovascular Disease

Subarachnoid Haemorrhage

Subdural Haematoma

Subglottic Stenosis

Superficial Thrombophlebitis, See Thrombosis

Supraventricular Tachycardia, See Heart, Arrhythmia

Surgery

Suxamethonium Allergy

Sydenham Chorea, See Rheumatic Fever

Syphilis

Syringomyelia

Systemic Lupus Erythematosus

T

Tachycardia, See Heart, Arrhythmia

Takayasu Arteritis, See Vasculitis

Tattoo, See Body Piercing

Tay Sachs Disease, See Inherited Disease

Temporal Arteritis, See Vasculitis

Temporal Lobectomy, See Neurosurgery and Epilepsy

Termination Of Pregnancy, See Pregnancy and Surgery

Testosterone Injections, See Hormone Replacement Therapy and Addiction and Drug Abuse

Tetralogy Of Fallot, See Heart, Congenital Defect

Tetraplegia, See Disabled Volunteer

Thalassaemia Major, See Haemoglobin Disorder

Thalassaemia Trait (Minor), See Haemoglobin Disorder

Thoracic Outlet Syndrome

Thrombocythemia, See Thrombocytosis

Thrombocytopenia

Thrombocytosis

Thrombophilia

Thrombophlebitis, See Thrombosis

Thrombosis

Thrush, See Candida Infection

Thyroid Disease

Thyrotoxicosis, See Thyroid Disease

Tick Typhus, See Rickettsial Infection

Tissue Or Organ Transplant

Toxoplasmosis

Transfusion

Transient Ischaemic Attack (TIA), See Cerebrovascular Disease

Transgender

Treacher-Collins Syndrome, See Inherited Disease

Trial, See Clinical Trial

Tricuspid Regurgitation, See Heart, Valve Disease

Tricuspid Stenosis, See Heart, Valve Disease

Tropical Viruses

Tropical viruses ALERTS

Trigeminal Neuralgia

Trypanosoma Cruzi Infection, See South American Trypanosomiasis

Tuberculosis

Turner Syndrome

Typhoid

U

Ulcerative Colitis, See Inflammatory Bowel Disease

Urticaria

Uterine Fibroid, See Fibroids

Uveitis, See Eye Disease

V

Vaccine, See Immunisation

Vaccination, See Immunisation

Varicella Zoster, See Chicken Pox

Varicose Veins

Vasculitis

Vasovagal Attack

Venesection

Ventricular Septal Defect, See Heart, Congenital Defect

Vestibular Schwannoma, See Acoustic Neuroma

Viral Haemorrhagic Fever

Visceral Leishmaniasis, See Leishmaniasis

Vitiligo

Von Recklinghausen Disease, See Neurofibromatosis

Von Willebrand Disease, See Bleeding Disorder

W

Warts, See Human Papilloma Virus

Wegener Granulomatosis, See Vasculitis

Weight

Weight loss medications

Weil Disease, See Leptospirosis

Werdnig-Hoffmann Disease, See Inherited Disease

West Nile Virus

Wilson Disease

Wolff-Parkinson-White Syndrome, See Heart, Arrhythmia

X

Y

Yaws

Yellow Fever, See Infection, Acute

Yellow Fever Vaccine, See Immunisation

Z

Zika Virus, See Tropical Viruses

Appendix 1 - Haematologic and biochemical testing at donor medical

The following haematological and biochemical tests are performed at the donor medical:

Full blood count

Urea and Electrolytes

Liver function tests

Bone function tests

Cholesterol

Random glucose

Coagulation screen (PT, APTT and fibrinogen)

ABO and Rh blood grouping

Pregnancy test (B-HCG), if relevant

Appendix 2 - Infectious disease marker testing at ET/CT and donor medical

The following infectious disease markers are tested for all donors at the donor medical:

HIV (P24 antigen and antibody)

Hepatitis B (surface antigen and core antibody)

Hepatitis C (antibody and RNA)

HTLV I+II (antibody)

Syphilis (antibody)

Toxoplama (antibody)

EBV (VCA/NA IgG)

CMV (IgG)

Varicella (IgG)


The following infectious disease markers may be tested if a relevant travel history is given by the donor, at the discretion of the harvest physician or Anthony Nolan medical officer:

Malarial antigen/antibodies

T.cruzi (Chagas disease) antibodies

West nile virus NAT

Appendix 3 - Other investigations at donor medical

Electrocardiogram (ECG)

Chest X-ray

Appendix 4 - Special consideration for donors in the Armed Forces

Guidance for Armed Forces donors

It is recognised that members of the Armed Forces will need to get permission from the Commanding Officer prior to donation. Certain occupations within the MOD, such as aircrew within the RAF, will not allow donation by bone marrow harvest unless it is to a family member, although peripheral blood stem cell donation is permitted.

As a consequence, members of the Armed Forces are permitted to join the register as ‘PBSC only’ if there are concerns about the impact of bone marrow harvest on their ability to fulfil their role, or concerns about possible impact on their career.

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